Predictors of rebleeding after initial hemostasis with epinephrine injection in high-risk ulcers

World Journal of Gastroenterology

Volumn 16, Issue 43, 2010, Pages 5490-5495

  Hu, Ming Luen ^a   Wu, Keng Liang ^a   Chiu, King Wah ^a   Chiu, Yi Chun ^a   Chou, Yeh Pin ^a   Tai, Wei Chen ^a   Hu, Tsung Hui ^a   Chiou, Shue Shian ^a   Chuah, Seng Kee ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Epinephrine injection; High risk ulcers; Initial hemostasis; Predictors; Rebleeding

Indexed keywords

ADRENALIN; HEMOGLOBIN; PROTON PUMP INHIBITOR;

ADULT; AGED; ANEMIA; ARTICLE; DIGESTIVE SYSTEM ULCER; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEMATEMESIS; HEMATOCHEZIA; HEMOSTASIS; HIGH RISK PATIENT; HUMAN; HYPOVOLEMIC SHOCK; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; PREDICTION; RESPIRATORY FAILURE; SEPSIS; SHOCK; THERMOCOAGULATION; UNIVARIATE ANALYSIS;

EID: 78649698033     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i43.5490     Document Type: Article

References (30)

1. Church NI, Palmer KR. Ulcers and nonvariceal bleeding. Endoscopy 2003; 35: 22-26.
2. Sugawa C, Joseph AL. Endoscopic interventional management of bleeding duodenal and gastric ulcers. Surg Clin North Am 1992; 72: 317-334.
3. Villanueva C, Balanzó J, Espinós JC, Fábrega E, Sáinz S, González D, Vilardell F. Endoscopic injection therapy of bleeding ulcer: a prospective and randomized comparison of adrenaline alone or with polidocanol. J Clin Gastroenterol 1993; 17: 195-200.
4. Consensus conference: Therapeutic endoscopy and bleeding ulcers. JAMA 1989; 262: 1369-1372.
5. Chung SC, Leung JW, Steele RJ, Crofts TJ, Li AK. Endoscopic injection of adrenaline for actively bleeding ulcers: a randomised trial. Br Med J (Clin Res Ed) 1988; 296: 1631-1633.
6. Oxner RB, Simmonds NJ, Gertner DJ, Nightingale JM, Burnham WR. Controlled trial of endoscopic injection treatment for bleeding from peptic ulcers with visible vessels. Lancet 1992; 339: 966-968.
7. Balanzó J, Sainz S, Such J, Espinós JC, Guarner C, Cussó X, Monés J, Vilardell F. Endoscopic hemostasis by local injection of epinephrine and polidocanol in bleeding ulcer. A prospective randomized trial. Endoscopy 1988; 20: 289-291.
8. Cook DJ, Guyatt GH, Salena BJ, Laine LA. Endoscopic therapy for acute nonvariceal upper gastrointestinal hemorrhage: a meta-analysis. Gastroenterology 1992; 102: 139-148.
9. Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut 1996; 38: 316-321.
10. Wong SK, Yu LM, Lau JY, Lam YH, Chan AC, Ng EK, Sung JJ, Chung SC. Prediction of therapeutic failure after adrenaline injection plus heater probe treatment in patients with bleeding peptic ulcer. Gut 2002; 50: 322-325.
11. Park CH, Joo YE, Kim HS, Choi SK, Rew JS, Kim SJ. A prospective, randomized trial comparing mechanical methods of hemostasis plus epinephrine injection to epinephrine injection alone for bleeding peptic ulcer. Gastrointest Endosc 2004; 60: 173-179.
12. Chung SS, Lau JY, Sung JJ, Chan AC, Lai CW, Ng EK, Chan FK, Yung MY, Li AK. Randomised comparison between adrenaline injection alone and adrenaline injection plus heat probe treatment for actively bleeding ulcers. BMJ 1997; 314: 1307-1311.
13. Calvet X, Vergara M, Brullet E, Gisbert JP, Campo R. Addition of a second endoscopic treatment following epinephrine injection improves outcome in high-risk bleedingulcers. Gastroenterology 2004; 126: 441-450.
14. Barkun AN, Martel M, Toubouti Y, Rahme E, Bardou M. Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses. Gastrointest Endosc 2009; 69: 786-799.
15. Marmo R, Rotondano G, Piscopo R, Bianco MA, D'Angella R, Cipolletta L. Dual therapy versus monotherapy in the endoscopic treatment of high-risk bleeding ulcers: a metaanalysis of controlled trials. Am J Gastroenterol 2007; 102: 279-289; quiz 469.
16. Andriulli A, Loperfido S, Focareta R, Leo P, Fornari F, Garripoli A, Tonti P, Peyre S, Spadaccini A, Marmo R, Merla A, Caroli A, Forte GB, Belmonte A, Aragona G, Imperiali G, Forte F, Monica F, Caruso N, Perri F. High- versus low-dose proton pump inhibitors after endoscopic hemostasis in patients with peptic ulcer bleeding: a multicentre, randomized study. Am J Gastroenterol 2008; 103: 3011-3018.
17. Adamsen S, Bendix J, Kallehave F, Moesgaard F, Nilsson T, Wille-Jørgensen P. Clinical practice and evidence in endoscopic treatment of bleeding peptic gastroduodenal ulcer. Scand J Gastroenterol 2007; 42: 318-323.
18. Tseng GY, Fang CT, Lin HJ, Yang HB, Tseng GC, Wang PC, Liao PC, Cheng YT, Huang CH. Efficacy of an intravenous proton pump inhibitor after endoscopic therapy with epinephrine injection for peptic ulcer bleeding in patients with uraemia: a case-control study. Aliment Pharmacol Ther 2009; 30: 406-413.
19. Bleau BL, Gostout CJ, Sherman KE, Shaw MJ, Harford WV, Keate RF, Bracy WP, Fleischer DE. Recurrent bleeding from peptic ulcer associated with adherent clot: a randomized study comparing endoscopic treatment with medical therapy. Gastrointest Endosc 2002; 56: 1-6.
20. Owens WD, Felts JA, Spitznagel EL Jr. ASA physical status classifications: a study of consistency of ratings. Anesthesiology 1978; 49: 239-243.
21. Patchett SE, Enright H, Afdhal N, O'Connell W, O'Donoghue DP. Clot lysis by gastric juice: an in vitro study. Gut 1989; 30: 1704-1707.
22. Leontiadis GI, Sharma VK, Howden CW. Proton pump inhibitor therapy for peptic ulcer bleeding: Cochrane collaboration meta-analysis of randomized controlled trials. Mayo Clin Proc 2007; 82: 286-296.
23. Palmer KR, Choudari CP. Endoscopic intervention in bleeding peptic ulcer. Gut 1995; 37: 161-164.
24. Swain P. What should be done when initial endoscopic therapy for bleeding peptic ulcer fails? Endoscopy 1995; 27: 321-328.
25. Lin HJ, Hsieh YH, Tseng GY, Perng CL, Chang FY, Lee SD. A prospective, randomized trial of large- versus small-volume endoscopic injection of epinephrine for peptic ulcer bleeding. Gastrointest Endosc 2002; 55: 615-619.
26. Park CH, Lee SJ, Park JH, Park JH, Lee WS, Joo YE, Kim HS, Choi SK, Rew JS, Kim SJ. Optimal injection volume of epinephrine for endoscopic prevention of recurrent peptic ulcer bleeding. Gastrointest Endosc 2004; 60: 875-880.
27. Godil A, DeGuzman L, Schilling RC 3rd, Khan SA, Chen YK. Recent nonsteroidal anti-inflammatory drug use increases the risk of early recurrence of bleeding in patients presenting with bleeding ulcer. Gastrointest Endosc 2000; 51: 146-151.
28. Vreeburg EM, de Bruijne HW, Snel P, Bartelsman JW, Rauws EA, Tytgat GN. Previous use of non-steroidal anti-inflammatory drugs and anticoagulants: the influence on clinical out-come of bleeding gastroduodenal ulcers. Eur J Gastroenterol Hepatol 1997; 9: 41-44.
29. Archimandritis A, Tzivras M, Sougioultzis S, Papaparaskevas I, Apostolopoulos P, Avlami A, Davaris PS. Rapid urease test is less sensitive than histology in diagnosing Helicobacter pylori infection in patients with non-variceal upper gastroin-testinal bleeding. J Gastroenterol Hepatol 2000; 15: 369-373.
30. Schilling D, Demel A, Nüsse T, Weidmann E, Riemann JF. Helicobacter pylori infection does not affect the early rebleeding rate in patients with peptic ulcer bleeding after successful endoscopic hemostasis: a prospective single-center trial. Endoscopy 2003; 35: 393-396.