Perioperative opioid requirements are decreased in hypoxic children living at altitude

Paediatric Anaesthesia

Volumn 20, Issue 12, 2010, Pages 1078-1083

  Rabbitts, Jennifer A ^a   Groenewald, Cornelius B ^a   Dietz, Niki M ^a   Morales, Carmen ^b   Räsänen, Jukka ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSIDAD DE SAN MARTÍN DE PORRES   (Peru)

Author keywords

altitude; children; hypoxia; opioid; pain < PACU; Peru

Indexed keywords

DEXAMETHASONE; FENTANYL; PARACETAMOL; PROPOFOL; SEVOFLURANE;

AGE; ALTITUDE; ANALGESIA; ANESTHESIA INDUCTION; ARTICLE; BODY WEIGHT; CHILD; DRUG DOSE TITRATION; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; OPERATION DURATION; OXYGEN SATURATION; PALATOPLASTY; PERU; PRIORITY JOURNAL; RECOVERY ROOM; SEA LEVEL; SLEEP APNEA SYNDROME;

ALTITUDE; ANALGESICS, OPIOID; ANOXIA; CHILD, PRESCHOOL; CLEFT LIP; CLEFT PALATE; FENTANYL; HUMANS; MOUTH ABNORMALITIES; PERIOPERATIVE CARE; PERU; RETROSPECTIVE STUDIES;

EID: 78649677604     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2010.03453.x     Document Type: Article

References (18)

1. Moss IR, Brown KA, Laferriere A,. Recurrent hypoxia in rats during development increases subsequent respiratory sensitivity to fentanyl. Anesthesiology 2006; 105: 715-718.
2. Laferriere A, Liu JK, Moss IR,. Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia. Brain Res Bull 2003; 59: 307-313.
3. Brown KA, Laferriere A, Lakheeram I, et al. Recurrent hypoxemia in children is associated with increased analgesic sensitivity to opiates. Anesthesiology 2006; 105: 665-669.
4. Brown KA, Laferriere A, Moss IR,. Recurrent hypoxemia in young children with obstructive sleep apnea is associated with reduced opioid requirement for analgesia. Anesthesiology 2004; 100: 806-810. discussion 805A.
5. Carroll RC, Beattie EC, Von Zastrow M, et al. Role of AMPA receptor endocytosis in synaptic plasticity. Nat Rev Neurosci 2001; 2: 315-324.
6. Bernardi L,. Heart rate and cardiovascular variability at high altitude. Conf Proc IEEE Eng Med Biol Soc 2007; 2007: 6679-6681.
7. Bernardi L, Passino C, Spadacini G, et al. Cardiovascular autonomic modulation and activity of carotid baroreceptors at altitude. Clin Sci (Lond) 1998; 95: 565-573.
8. Gulli G, Claydon VE, Slessarev M, et al. Autonomic regulation during orthostatic stress in highlanders: comparison with sea-level residents. Exp Physiol 2007; 92: 427-435.
9. Hainsworth R, Drinkhill MJ, Rivera-Chira M,. The autonomic nervous system at high altitude. Clin Auton Res 2007; 17: 13-19.
10. Claydon VE, Norcliffe LJ, Moore JP, et al. Orthostatic tolerance and blood volumes in Andean high altitude dwellers. Exp Physiol 2004; 89: 565-571.
11. Moore JP, Claydon VE, Norcliffe LJ, et al. Carotid baroreflex regulation of vascular resistance in high-altitude Andean natives with and without chronic mountain sickness. Exp Physiol 2006; 91: 907-913.
12. Bruehl S, Chung OY,. Interactions between the cardiovascular and pain regulatory systems: an updated review of mechanisms and possible alterations in chronic pain. Neurosci Biobehav Rev 2004; 28: 395-414.
13. Duschek S, Muck I, Reyes Del Paso GA,. Relationship between baroreceptor cardiac reflex sensitivity and pain experience in normotensive individuals. Int J Psychophysiol 2007; 65: 193-200.
14. Droste C, Kardos A, Brody S, et al. Baroreceptor stimulation: pain perception and sensory thresholds. Biol Psychol 1994; 37: 101-113.
15. Rau H, Brody S, Larbig W, et al. Effects of PRES baroreceptor stimulation on thermal and mechanical pain threshold in borderline hypertensives and normotensives. Psychophysiology 1994; 31: 480-485.
16. Chung OY, Bruehl S, Diedrich L, et al. Baroreflex sensitivity associated hypoalgesia in healthy states is altered by chronic pain. Pain 2008; 138: 87-97.
17. Saavedra JM,. Spontaneously (genetic) hypertensive rats: naloxone-reversible and propranolol-reversible decrease in pain sensitivity. Experientia 1981; 37: 1002-1003.
18. Brown KA,. Intermittent hypoxia and the practice of anesthesia. Anesthesiology 2009; 110: 922-927.