The Nobel Prize in Physiology or Medicine 2009 "for telomere biology" and its relevance to cancer and related diseases

Clinical and Translational Oncology

Volumn 12, Issue 10, 2010, Pages 647-649

  Perona, Rosario ^a  

^a CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DYSKERIN; N(G) NITROARGININE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE;

CELL DIVISION; CHROMOSOME REPLICATION; CHROMOSOME STRUCTURE; CLINICAL RESEARCH; DNA PROTEIN COMPLEX; DOUBLE STRANDED DNA BREAK; DROSOPHILA MELANOGASTER; EDITORIAL; ENZYME ACTIVITY; ENZYME DEFICIENCY; FIBROBLAST; HUMAN; LIFESTYLE; MAIZE; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; POLYMERASE CHAIN REACTION; TELOMERE; TETRAHYMENA THERMOPHILA;

ANIMALS; GENETICS; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; NEOPLASMS; NOBEL PRIZE; TELOMERE;

EID: 78649674877     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-010-0572-y     Document Type: Editorial

References (29)

1. H.J. Müller 1938 Bar duplication Collecting Net (Woods Hole) 13 181 198
2. B. McClintock 1939 The behavior in successive nuclear divisions of a chromosome broken at meiosis Proc Natl Acad Sci U S A 25 405 416 1:STN:280:DC%2BD28zhvV2rtg%3D%3D 10.1073/pnas.25.8.405 16577924
3. B. McClintock 1941 The stability of broken ends of chromosomes in Zea mays Genetics 28 234 282
4. L. Hayflick P.S. Moorhead 1961 The serial cultivation of human diploid cell strains Exp Cell Res 25 585 621 10.1016/0014-4827(61)90192-6
5. J.D. Watson 1972 Origin of concatemeric T7 DNA Nat New Biol 239 197 201 1:CAS:528:DyaE3sXht1yjsQ%3D%3D 10.1038/239197a0 4507727
6. A.M. Olovnikov 1971 Principle of marginotomy in template synthesis of polynucleotides Dokl Akad Nauk SSSR 201 1496 1499 1:CAS:528:DyaE38XhtlOjsbs%3D 5158754
7. A.M. Olovnikov 1973 A theory of marginotomy. The incomplete copying of template margin in enzymatic synthesis of polynucleotides and biological significance of the phenomenon J Theor Biol 41 181 190 1:CAS:528: DyaE3sXltleks7k%3D 10.1016/0022-5193(73)90198-7 4754905
8. E.H. Blackburn G.J. Gall 1978 A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena J Mol Biol 120 33 53 1:CAS:528:DyaE1cXktVejsbc%3D 10.1016/0022-2836(78)90294-2 642006 (Pubitemid 8312910)
9. J.W. Szostak E.H. Blackburn 1982 Cloning yeast telomeres on linear plasmid vectors Cell 29 245 255 1:CAS:528:DyaL38XktlCisbg%3D 10.1016/0092-8674(82)90109-X 6286143
10. C.W. Greider E.H. Blackburn 1985 Identification of a specific telomere terminal transferase activity in Tetrahymena extracts Cell 43 405 413 1:CAS:528:DyaL28Xot12itQ%3D%3D 10.1016/0092-8674(85)90170-9 3907856
11. C.W. Greider E.H. Blackburn 1987 The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity Cell 51 887 898 1:CAS:528:DyaL1cXptVKhsQ%3D%3D 10.1016/0092-8674(87)90576-9 3319189
12. V. Lundblad J.W. Szostak 1989 A mutant with a defect in telomere elongation leads to senescence in yeast Cell 57 633 643 1:CAS:528: DyaK3cXntlKhtA%3D%3D 10.1016/0092-8674(89)90132-3 2655926
13. C.B. Harley A.B. Futcher C.W. Greider 1990 Telomeres shorten during ageing of human fibroblasts Nature 345 458 460 1:CAS:528:DyaK3cXksFKntb4%3D 10.1038/345458a0 2342578 (Pubitemid 20178256)
14. N.W. Kim M.A. Piatyszek K.R. Prowse, et al. 1994 Specific association of human telomerase activity with immortal cells and cancer Science 266 2011 2015 1:CAS:528:DyaK2MXisl2lu7g%3D 10.1126/science.7605428 7605428
15. M.A. Blasco H.W. Lee M.P. Hande, et al. 1997 Telomere shortening and tumor formation by mouse cells lacking telomerase RNA Cell 91 25 34 1:CAS:528:DyaK2sXmslGgt7w%3D 10.1016/S0092-8674(01)80006-4 9335332 (Pubitemid 27431310)
16. M.A. Blasco 2005 Telomeres and human disease: ageing, cancer and beyond Nat Rev Genet 6 611 622 1:CAS:528:DC%2BD2MXntFeqtbw%3D 10.1038/nrg1656 16136653 (Pubitemid 41044298)
17. T.M. Bryan R.R. Reddel 1997 Telomere dynamics and telomerase activity in in vitro immortalised human cells Eur J Cancer 33 767 773 1:CAS:528: DyaK2sXjvF2nurY%3D 10.1016/S0959-8049(97)00065-8 9282115 (Pubitemid 27239487)
18. D. Hanahan R.A. Weinberg 2000 The hallmarks of cancer Cell 100 57 70 1:CAS:528:DC%2BD3cXks1CktA%3D%3D 10.1016/S0092-8674(00)81683-9 10647931
19. L. Deville J. Hillion M. Lanotte, et al. 2006 Diagnostics, prognostic and therapeutic exploitation of telomeres and telomerase in leukemias Curr Pharm Biotechnol 7 171 183 1:CAS:528:DC%2BD28XnslOku7s%3D 10.2174/138920106777549768 16789902 (Pubitemid 43881081)
20. F. Pendino I. Tarkanyi C. Dudognon, et al. 2006 Telomeres and telomerase: pharmacological targets for new anticancer strategies? Curr Cancer Drug Targets 6 147 180 1:CAS:528:DC%2BD28XislSmsb8%3D 10.2174/156800906776056482 16529544
21. R.H. Vonderheide 2008 Prospects and challenges of building a cancer vaccine targeting telomerase Biochimie 90 173 180 1:CAS:528:DC%2BD2sXhsVSqu7vM 10.1016/j.biochi.2007.07.005 17716803 (Pubitemid 350216207)
22. J.R. Mitchell E. Wood K. Collins 1999 A telomerase component is defective in the human disease dyskeratosis congenita Nature 402 551 555 1:CAS:528:DyaK1MXotFKltr8%3D 10.1038/990141 10591218
23. P.J. Mason D.B. Wilson M. Bessler 2005 Dyskeratosis congenita: a disease of dysfunctional telomere maintenance Curr Mol Med 5 159 170 1:CAS:528:DC%2BD2MXjslaju70%3D 10.2174/1566524053586581 15974869 (Pubitemid 40601643)
24. M. Hills P.M. Lansdorp 2009 Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies Ann N Y Acad Sci 1176 178 190 1:CAS:528:DC%2BD1MXhtlKqt7fI 10.1111/j.1749-6632.2009.04565.x 19796246
25. M. Kirwan I. Dokal 2009 Dyskeratosis congenita, stem cells and telomeres Biochim Biophys Acta 1792 371 379 1:CAS:528:DC%2BD1MXksVaqsbk%3D 19419704
26. M.Y. Armanios J.J. Chen J.D. Cogan, et al. 2007 Telomerase mutations in families with idiopathic pulmonary fibrosis N Engl J Med 356 1317 1326 1:CAS:528:DC%2BD2sXjsFKhsL0%3D 10.1056/NEJMoa066157 17392301 (Pubitemid 46513297)
27. J.K. Alder J.J. Chen L. Lancaster, et al. 2008 Short telomeres are a risk factor for idiopathic pulmonary fibrosis Proc Natl Acad Sci U S A 105 13051 13056 1:CAS:528:DC%2BD1cXhtFSitLbJ 10.1073/pnas.0804280105 18753630
28. A.M. Valdes T. Andrew J.P. Gardner, et al. 2005 Obesity, cigarette smoking, and telomere length in women Lancet 366 662 664 1:CAS:528: DC%2BD2MXosVajsbo%3D 10.1016/S0140-6736(05)66630-5 16112303 (Pubitemid 41176019)
29. E.S. Epel E.H. Blackburn J. Lin, et al. 2004 Accelerated telomere shortening in response to life stress Proc Natl Acad Sci U S A 101 17312 17315 1:CAS:528:DC%2BD2cXhtFansr%2FO 10.1073/pnas.0407162101 15574496 (Pubitemid 39627816)