FliZ induces a kinetic switch in flagellar gene expression

Journal of Bacteriology

Volumn 192, Issue 24, 2010, Pages 6477-6481

  Saini, Supreet ^a   Koirala, Santosh ^a   Floess, Emily ^a   Mears, Patrick J ^b   Chemla, Yann R ^b   Golding, Ido ^b   Aldridge, Christine ^c   Aldridge, Phillip D ^c   Rao, Christopher V ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b University of Illinois at Urbana Champaign   (United States)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PROTEIN FLIZ; UNCLASSIFIED DRUG;

ARTICLE; GENE EXPRESSION; GENE FUNCTION; KINETICS; MOLECULAR DYNAMICS; NONHUMAN; PHENOTYPE; POSITIVE FEEDBACK; PRIORITY JOURNAL; SALMONELLA ENTERICA;

BACTERIAL PROTEINS; FLAGELLA; GENE EXPRESSION REGULATION, BACTERIAL; KINETICS; SALMONELLA ENTERICA; TIME FACTORS;

SALMONELLA ENTERICA;

EID: 78649672753     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.00751-10     Document Type: Article

References (28)

1. Aldridge, P., J. Karlinsey, and K. T. Hughes. 2003. The type III secretion chaperone FlgN regulates flagellar assembly via a negative feedback loop containing its chaperone substrates FlgK and FlgL. Mol. Microbiol. 49:1333-1345.
2. Aldridge, P. D., J. E. Karlinsey, C. Aldridge, C. Birchall, D. Thompson, J. Yagasaki, and K. T. Hughes. 2006. The flagellar-specific transcription factor, sigma28, is the type III secretion chaperone for the flagellar-specific antisigma28 factor FlgM. Genes Dev. 20:2315-2326.
3. Aldridge, C., K. Poonchareon, S. Saini, T. Ewen, A. Soloyva, C. V. Rao, K. Imada, T. Minamino, and P. D. Aldridge. 14 October 2010, posting date. The interaction dynamics of a negative feedback loop regulates flagellar number in Salmonella enterica serovar Typhimurium. Mol. Microbiol. doi:10.1111/j.1365- 2958.2010.07415.x.
4. Brown, J. D., S. Saini, C. Aldridge, J. Herbert, C. V. Rao, and P. D. Aldridge. 2008. The rate of protein secretion dictates the temporal dynamics of flagellar gene expression. Mol. Microbiol. 70:924-937.
5. Chadsey, M. S., and K. T. Hughes. 2001. A multipartite interaction between Salmonella transcription factor sigma28 and its anti-sigma factor FlgM: implications for sigma28 holoenzyme destabilization through stepwise binding. J. Mol. Biol. 306:915-929.
6. Chadsey, M. S., J. E. Karlinsey, and K. T. Hughes. 1998. The flagellar anti-sigma factor FlgM actively dissociates Salmonella typhimurium sigma28 RNA polymerase holoenzyme. Genes Dev. 12:3123-3136.
7. Chilcott, G. S., and K. T. Hughes. 2000. Coupling of flagellar gene expression to flagellar assembly in Salmonella enterica serovar Typhimurium and Escherichia coli. Microbiol. Mol. Biol. Rev. 64:694-708.
8. Cozy, L. M., and D. B. Kearns. 2010. Gene position in a long operon governs motility development in Bacillus subtilis. Mol. Microbiol. 76:273-285.
9. Gillen, K. L., and K. T. Hughes. 1993. Transcription from two promoters and autoregulation contribute to the control of expression of the Salmonella typhimurium flagellar regulatory gene flgM. J. Bacteriol. 175:7006-7015.
10. Hughes, K. T., K. L. Gillen, M. J. Semon, and J. E. Karlinsey. 1993. Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator. Science 262:1277-1280.
11. Ikebe, T., S. Iyoda, and K. Kutsukake. 1999. Promoter analysis of the class 2 flagellar operons of Salmonella. Genes Genet. Syst. 74:179-183.
12. Ikebe, T., S. Iyoda, and K. Kutsukake. 1999. Structure and expression of the fliA operon of Salmonella typhimurium. Microbiology 145:1389-1396.
13. Iyoda, S., T. Kamidoi, K. Hirose, K. Kutsukake, and H. Watanabe. 2001. A flagellar gene fliZ regulates the expression of invasion genes and virulence phenotype in Salmonella enterica serovar Typhimurium. Microb. Pathog. 30:81-90.
14. Kalir, S., and U. Alon. 2004. Using a quantitative blueprint to reprogram the dynamics of the flagella gene network. Cell 117:713-720.
15. Kalir, S., J. McClure, K. Pabbaraju, C. Southward, M. Ronen, S. Leibler, M. G. Surette, and U. Alon. 2001. Ordering genes in a flagella pathway by analysis of expression kinetics from living bacteria. Science 292:2080-2083.
16. Karlinsey, J. E., J. Lonner, K. L. Brown, and K. T. Hughes. 2000. Translation/ secretion coupling by type III secretion systems. Cell 102:487-497.
17. Kutsukake, K., T. Ikebe, and S. Yamamoto. 1999. Two novel regulatory genes, fliT and fliZ, in the flagellar regulon of Salmonella. Genes Genet. Syst. 74:287-292.
18. Lin, D., C. V. Rao, and J. M. Slauch. 2008. The Salmonella SPI1 type three secretion system responds to periplasmic disulfide bond status via the flagellar apparatus and the RcsCDB system. J. Bacteriol. 190:87-97.
19. Liu, X., N. Fujita, A. Ishihama, and P. Matsumura. 1995. The C-terminal region of the alpha subunit of Escherichia coli RNA polymerase is required for transcriptional activation of the flagellar level II operons by the FlhD/ FlhC complex. J. Bacteriol. 177:5186-5188.
20. Liu, X., and P. Matsumura. 1995. An alternative sigma factor controls transcription of flagellar class-III operons in Escherichia coli: gene sequence, overproduction, purification and characterization. Gene 164:81-84.
21. Liu, X., and P. Matsumura. 1994. The FlhD/FlhC complex, a transcriptional activator of the Escherichia coli flagellar class II operons. J. Bacteriol. 176: 7345-7351.
22. Macnab, R. M. 2003. How bacteria assemble flagella. Annu. Rev. Microbiol. 57:77-100.
23. Ohnishi, K., K. Kutsukake, H. Suzuki, and T. Lino. 1992. A novel transcriptional regulation mechanism in the flagellar regulon of Salmonella typhimurium: an antisigma factor inhibits the activity of the flagellum-specific sigma factor, sigma F. Mol. Microbiol. 6:3149-3157.
24. Saini, S., J. D. Brown, P. D. Aldridge, and C. V. Rao. 2008. FliZ Is a posttranslational activator of FlhD4C2-dependent flagellar gene expression. J. Bacteriol. 190:4979-4988.
25. Saini, S., J. R. Ellermeier, J. M. Slauch, and C. V. Rao. 2010. The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. PLoS Pathog. 6:e1001025. (Erratum, 6:doi:10.1371/ annotation/df7e26bc-4c62-43b4-865f-a39274d98ab3.)
26. Saini, S., J. A. Pearl, and C. V. Rao. 2009. Role of FimW, FimY, and FimZ in regulating the expression of type I fimbriae in Salmonella enterica serovar Typhimurium. J. Bacteriol. 191:3003-3010.
27. Wang, S., R. T. Fleming, E. M. Westbrook, P. Matsumura, and D. B. McKay. 2006. Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription. J. Mol. Biol. 355:798-808.
28. Yamamoto, S., and K. Kutsukake. 2006. FliT acts as an anti-FlhD2C2 factor in the transcriptional control of the flagellar regulon in Salmonella enterica serovar Typhimurium. J. Bacteriol. 188:6703-6708.