Probing the active site of the sugar isomerase domain from E. coli arabinose-5-phosphate isomerase via X-ray crystallography

Protein Science

Volumn 19, Issue 12, 2010, Pages 2430-2439

  Gourlay, Louise J ^a   Sommaruga, Silvia ^b   Nardini, Marco ^a   Sperandeo, Paola ^b   Dehò, Gianni ^a   Polissi, Alessandra ^b   Bolognesi, Martino ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

3 deoxy D manno octulosonate synthesis; Antimicrobial development; D arabinose 5 phosphate isomerase; Gram negative bacteria; Lipopolysaccharide biogenesis; Three dimensional protein structure

Indexed keywords

ARABINOSEPHOSPHATE ISOMERASE; BACTERIAL ENZYME; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIUM MUTANT; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

ALDOSE-KETOSE ISOMERASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

NEGIBACTERIA;

EID: 78649667348     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.525     Document Type: Article

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