Acceleration of consolidation period by thrombin peptide 508 in tibial distraction osteogenesis in rats

British Journal of Oral and Maxillofacial Surgery

Volumn 48, Issue 8, 2010, Pages 633-636

  Cakarer, S ^a   Olgac, V ^a   Aksakalli, N ^a   Tang, A ^b   Keskin, C ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b Targa Therapeutics   (United States)

Author keywords

Distraction osteogenesis; Rat; Thrombin peptide; Tibia; TP508

Indexed keywords

THROMBIN; THROMBIN PEPTIDE 508; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE REGENERATION; CLINICAL EVALUATION; CONTROLLED STUDY; CONVALESCENCE; DISTRACTION OSTEOGENESIS; DRUG DOSE COMPARISON; DRUG EFFICACY; MALE; MORPHOMETRICS; NONHUMAN; OSSIFICATION; RAT; TIBIA DISTRACTION OSTEOGENESIS; TREATMENT OUTCOME;

ANIMALS; BONE MARROW; BONE REGENERATION; BONE SCREWS; COLLAGEN; CONNECTIVE TISSUE; EXTERNAL FIXATORS; IMAGE PROCESSING, COMPUTER-ASSISTED; INJECTIONS, SUBCUTANEOUS; MALE; OSTEOGENESIS; OSTEOGENESIS, DISTRACTION; PEPTIDE FRAGMENTS; PHOTOGRAPHY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; THROMBIN; TIBIA; TIME FACTORS; WOUND HEALING;

EID: 78649659248     PISSN: 02664356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bjoms.2009.11.009     Document Type: Article

References (25)

1. I.H. Choi, C.Y. Chung, T.J. Cho, and W.J. Yoo Angiogenesis and mineralization during distraction osteogenesis J Korean Med Sci 17 2002 435 437
2. L.W. Zheng, M.C.M. Wong, A.B.M. Rabie, and L.K. Cheung Evaluation of recombinant human bone morphogenetic protein-2 in mandibular distraction osteogenesis in rabbits: effect of dosage and number of doses on formation of bone Br J Oral Maxillofac Surg 44 2006 487 494
3. M.O. Al-Sebaei, E. Gagari, and M. Papageorge Mandibular distraction osteogenesis: a rabbit model using a novel experimental design J Oral Maxillofac Surg 63 2005 664 672
4. E.L. Hedberg, H.C. Kroese-Deutman, and C.K. Shih Effect of varied release kinetics of the osteogenic thrombin peptide TP508 from biodegradable, polymeric scaffolds on bone formation in vivo J Biomed Mater Res A 15 2005 343 353
5. C. Fife, J.T. Mader, and J. Stone Thrombin peptide Chrysalin stimulates healing of diabetic foot ulcers in a placebo controlled phase I/II study Wound Repair Regen 15 2007 23 34
6. M.R. Sheller, R.S. Crowther, and J.H. Kinney Repair of rabbit segmental defects with the thrombin peptide, TP508 J Orthop Res 22 2004 1094 1099
7. H. Wang, X. Li, and E. Tomin Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis J Orthop Res 23 2005 671 679
8. L.R. Amir, G. Li, T. Schoenmaker, V. Everts, and A.L. Bronckers Effect of thrombin peptide 508 (TP508) on bone healing during distraction osteogenesis in rabbit tibia Cell Tissue Res 330 2007 35 44
9. G. Li, J.T. Ryaby, D.H. Carney, and H. Wang Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis J Orthop Res 23 2005 196 202
10. Y. Wang, C. Wan, G. Szöke, J.T. Ryaby, and G. Li Local injection of thrombin-related peptide (TP508) in PPF/PLGA microparticles-enhanced bone formation during distraction osteogenesis J Orthop Res 26 2008 539 546
11. G. Swennen, R. Dempf, and H. Schliephake Craniofacial distraction osteogenesis: a review of the literature. Part II. Experimental studies Int J Oral Maxillofac Surg 31 2002 123 135
12. J. Aronson, X.C. Shen, R.A. Skinner, W.R. Hogue, T.M. Badger, and C.K. Lumpkin Jr Rat model of distraction osteogenesis J Orthop Res 15 1997 221 226
13. B.E. Williams, G.J. King, Z.J. Liu, and K.L. Rafferty Sequential histomorphometric analysis of regenerate osteogenesis following mandibular distraction in the rat Arch Oral Biol 50 2005 497 506
14. J. Aronson, B. Good, C. Stewart, B. Harrison, and J. Harp Preliminary studies of mineralization during distraction osteogenesis Clin Orthop Relat Res 250 1990 43 49
15. U.M. Djasim, E.B. Wolvius, J.W. van Neck, H. Weinans, and K.G. ven der Wal Recommandations for optimal distraction protocols for various animal models on the basis of a systematic review of the literature Int J Oral Maxillofac Surg 36 2007 877 883
16. R. Aleksyniene, H. Eckardt, K. Bundgaard, M. Lind, and I. Hvid Effects of parathyroid hormone on newly regenerated bone during distraction osteogenesis in a rabbit tibial lengthening model. A pilot study Medicina (Kaunas) 42 2006 38 48
17. A. Girod, T. Roger, P. Breton, and P. Bouletreau Experimental study of mineralization in mandibular bone distraction with irradiation during the consolidation phase J Craniomaxillofac Surg 33 2005 386 394
18. R.C. Hamdy, M. Amako, and L. Beckman Effects of osteogenic protein-1 on distraction osteogenesis in rabbits Bone 33 2003 248 255
19. T. Kossmann, G. Giebel, and A. Glombitza Rat model for limb lengthening by callus distraction Res Exp Med (Berl) 193 1993 13 20
20. A. Aiga, K. Asaumi, and Y.J. Lee Expression of neurotrophins and their receptors tropomyosin-related kinases (Trk) under tension-stress during distraction osteogenesis Acta Med Okayama 60 2006 267 277
21. D.H. Carney, R. Mann, and W.R. Redin Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor-activating peptides J Clin Invest 89 1992 1469 1477
22. B.M. Hanratty, J.T. Ryaby, X.H. Pan, and G. Li Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model J Orthop Surg Res 4 2009 1
23. K.E. Rodgers Technology evaluation: Chrysalin (Orthologic) Curr Opin Mol Ther 7 2005 264 272
24. J. Stiernberg, W.R. Redin, W.S. Warner, and D.H. Carney The role of thrombin and thrombin receptor activating peptide (TRAP-508) in initiation of tissue repair Thromb Haemost 70 1993 158 162
25. E. Tomin, J. Lane, S.B. Doty, and J. Ryaby Chrysalin TP508: a new small peptide adjuvant for spinal fusion Spine J 4 2004 S26