MR spectroscopy findings in early stages of motor neuron disease

American Journal of Neuroradiology

Volumn 31, Issue 10, 2010, Pages 1799-1806

  Van Der Graaff, M Maaike ^a   Lavini, C ^a   Akkerman, E M ^a   Majoie, Ch B ^a   Nederveen, A J ^a   Zwinderman, A H ^a   Brugman, F ^b   Van Den Berg, L H ^b   De Jong, J M B V ^a   De Visser, M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; GLUTAMINE; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN CELL; CONTROLLED STUDY; DATA ANALYSIS; DISEASE COURSE; DISEASE DURATION; FEMALE; FOLLOW UP; GLIA CELL; HUMAN; HYPERACTIVITY; MALE; METABOLIC REGULATION; MOTOR CORTEX; MOTOR NEURON DISEASE; NERVE CELL DEGENERATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHENOTYPE; PROGRESSIVE MUSCULAR ATROPHY; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RATING SCALE; VOXEL BASED MORPHOMETRY;

AGED; AGED, 80 AND OVER; COHORT STUDIES; EARLY DIAGNOSIS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MOTOR CORTEX; MOTOR NEURON DISEASE; MOTOR NEURONS; NEUROGLIA; PHENOTYPE; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; ROC CURVE;

EID: 78649650723     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A2217     Document Type: Article

References (41)

1. Czaplinski A, Yen AA, Simpson EP, et al. Predictability of disease progression in amyotrophic lateral sclerosis. Muscle Nerve 2006;34:702-08
2. Zoccolella S, Beghi E, Palagano G, et al. Analysis of survival and prognostic factors in amyotrophic lateral sclerosis: a population-based study. J Neurol Neurosurg Psychiatry 2008;79:33-37
3. Chou SM, Norris FH. Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons. Muscle Nerve 1993;16:864-69
4. Eisen A. Motor neuron disease: a primary disorder of corticomotoneurons? Muscle Nerve 1995;18:1080-81
5. Pamphlett R, Kril J, Hng TM. Motor neuron disease: a primary disorder of corticomotoneurons? Muscle Nerve 1995;18:314-18
6. Visser J, van den Berg-Vos RM, Franssen H, et al. Mimic syndromes in sporadic cases of progressive spinal muscular atrophy. Neurology 2002;58:1593-96 (Pubitemid 34602887)
7. Ince PG, Evans J, Knopp M, et al. Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS. Neurology 2003;60:1252-58 (Pubitemid 36460979)
8. Kim WK, Liu X, Sandner J, et al. Study of 962 patients indicates progressive muscular atrophy is a form of ALS. Neurology 2009;73:1686-92
9. Visser J, van den Berg-Vos RM, Franssen H, et al. Disease course and prognostic factors of progressive muscular atrophy. Arch Neurol 2007;64:522-28 (Pubitemid 46588340)
10. Gordon PH, Cheng B, Katz IB, et al. The natural history of primary lateral sclerosis. Neurology 2006;66:647-53
11. Pringle CE, Hudson AJ, Munoz DG, et al. Primary lateral sclerosis: clinical features, neuropathology and diagnostic criteria. Brain 1992;115(pt 2):495-520
12. Demougeot C, Garnier P, Mossiat C, et al. N-acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. J Neurochem 2001;77:408-15
13. Pioro EP, Antel JP, Cashman NR, et al. Detection of cortical neuron loss in motor neuron disease by proton magnetic resonance spectroscopic imaging in vivo. Neurology 1994;44:1933-38
14. Block W, Karitzky J, Traber F, et al. Proton magnetic resonance spectroscopy of the primary motor cortex in patients with motor neuron disease: subgroup analysis and follow-up measurements. Arch Neurol 1998;55:931-36
15. Chan S, Shungu DC, Douglas-Akinwande A, et al. Motor neuron diseases: comparison of single-voxel proton MR spectroscopy of the motor cortex with MR imaging of the brain. Radiology 1999;212:763-69
16. Gredal O, Rosenbaum S, Topp S, et al. Quantification of brain metabolites in amyotrophic lateral sclerosis by localized proton magnetic resonance spectroscopy. Neurology 1997;48:878-81 (Pubitemid 27175609)
17. Pohl C, Block W, Karitzky J, et al. Proton magnetic resonance spectroscopy of the motor cortex in 70 patients with amyotrophic lateral sclerosis. Arch Neurol 2001;58:729-35 (Pubitemid 32423044)
18. Brand A, Richter-Landsberg C, Leibfritz D. Multinuclear NMR studies on the energy metabolism of glial and neuronal cells. Dev Neurosci 1993;15:289-98
19. Kalra S, Hanstock CC, Martin WR, et al. Detection of cerebral degeneration in amyotrophic lateral sclerosis using high-field magnetic resonance spectroscopy. Arch Neurol 2006;63:1144-48
20. De Stefano N, Filippi M, Miller D, et al. Guidelines for using proton MR spectroscopy in multicenter clinical MS studies. Neurology 2007;69:1942-52
21. Pioro EP, Majors AW, Mitsumoto H, et al. 1H-MRS evidence of neurodegeneration and excess glutamate + glutamine in ALS medulla. Neurology 1999;53:71-79 (Pubitemid 29329651)
22. Brooks BR, Miller RG, Swash M, et al. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293-99
23. Brugman F, Wokke JH, Scheffer H, et al. Spastin mutations in sporadic adultonset upper motor neuron syndromes. Ann Neurol 2005;58:865-69 (Pubitemid 41746875)
24. Brugman F, Scheffer H, Wokke JH, et al. Paraplegin mutations in sporadic adult-onset upper motor neuron syndromes. Neurology 2008;71:1500-05
25. Kent-Braun JA, Walker CH, Weiner MW, et al. Functional significance of upper and lower motor neuron impairment in amyotrophic lateral sclerosis. Muscle Nerve 1998;21:762-68
26. Cedarbaum JM, Stambler N, Malta E, et al. The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function-BDNF ALS Study Group (Phase III). J Neurol Sci 1999;169:13-21
27. Ellis CM, Simmons A, Jones DK, et al. Diffusion tensor MRI assesses corticospinal tract damage in ALS. Neurology 1999;53:1051-58 (Pubitemid 29442122)
28. Naidich TP, Grant JL, Altman N, et al. The developing cerebral surface: preliminary report on the patterns of sulcal and gyral maturation-anatomy, ultrasound, and magnetic resonance imaging. Neuroimaging Clin N Am 1994;4:201-40 (Pubitemid 24179807)
29. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-79
30. Sarchielli P, Pelliccioli GP, Tarducci R, et al. Magnetic resonance imaging and 1H-magnetic resonance spectroscopy in amyotrophic lateral sclerosis. Neuroradiology 2001;43:189-97 (Pubitemid 32194473)
31. Czaplinski A, Yen AA, Appel SH. Amyotrophic lateral sclerosis: early predictors of prolonged survival. J Neurol 2006;253:1428-36 (Pubitemid 44963428)
32. Cima V, Logroscino G, D'Ascenzo C, et al. Epidemiology of ALS in Padova district, Italy, from 1992 to 2005. Eur J Neurol 2009;16:920-24. Epub 2009 Mar 31
33. Czaplinski A, Yen AA, Simpson EP, et al. Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? Arch Neurol 2006;63:1139-43
34. Zhai P, Pagan F, Statland J, et al. Primary lateral sclerosis: a heterogeneous disorder composed of different subtypes? Neurology 2003;60:1258-65
35. Boillee S, Yamanaka K, Lobsiger CS, et al. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006;312:1389-92
36. Cwik VA, Hanstock CC, Allen PS, et al. Estimation of brainstem neuronal loss in amyotrophic lateral sclerosis with in vivo proton magnetic resonance spectroscopy. Neurology 1998;50:72-77
37. Ellis CM, Simmons A, Andrews C, et al. A proton magnetic resonance spectroscopic study in ALS: correlation with clinical findings. Neurology 1998;51:1104-09 (Pubitemid 28473408)
38. Kaufmann P, Pullman SL, Shungu DC, et al. Objective tests for upper motor neuron involvement in amyotrophic lateral sclerosis (ALS). Neurology 2004;62:1753-57
39. Mitsumoto H, Ulug AM, Pullman SL, et al. Quantitative objective markers for upper and lower motor neuron dysfunction in ALS. Neurology 2007;68:1402-10 (Pubitemid 46659092)
40. Rule RR, Schuff N, Miller RG, et al. Gray matter perfusion correlates with disease severity in ALS. Neurology 2010;74:821-27
41. Miller TM, Johnston SC. Should the Babinski sign be part of the routine neurologic examination? Neurology 2005;65:1165-68