Chromosomal integration of the HHV-6 genome as a possible cause of HHV-6 detection in cardiac tissues

Journal of Clinical Pathology

Volumn 63, Issue 12, 2010, Pages 1129-1130

  Strenger, Volker ^a   Aberle, Stephan W ^b   Wendelin, Gerald ^a   Pfurtscheller, Klaus ^a   Nacheva, Elisabeth P ^c   Zobel, Gerfried ^a   Nagel, Bert ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; CARDIOTONIC AGENT; DIURETIC AGENT; FOSCARNET SODIUM; GANCICLOVIR; IMMUNOGLOBULIN; INOTROPIC AGENT;

CASE REPORT; CHILD; CHROMOSOME REARRANGEMENT; CONGENITAL HEART DISEASE; CONGESTIVE CARDIOMYOPATHY; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; ECHOCARDIOGRAPHY; FEMALE; HAIR FOLLICLE; HEART HEMODYNAMICS; HUMAN; HUMAN HERPESVIRUS 6; HUMAN TISSUE; LETTER; MYOCARDITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; RESUSCITATION; VIRUS DETECTION; VIRUS GENOME; VIRUS INFECTION;

CARDIOMYOPATHY, DILATED; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; DNA, VIRAL; FEMALE; HEART DEFECTS, CONGENITAL; HERPESVIRUS 6, HUMAN; HUMANS; MYOCARDITIS; ROSEOLOVIRUS INFECTIONS; VIRUS INTEGRATION;

EID: 78649632830     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2010.079277     Document Type: Letter

References (5)

1. Comar M, D'Agaro P, Campello C, et al. Human herpes virus 6 in archival cardiac tissues from children with idiopathic dilated cardiomyopathy or congenital heart disease. J Clin Pathol 2009;62:80-3.
2. Clark DA, Ward KN. Importance of chromosomally integrated HHV-6A and -6B in the diagnosis of active HHV-6 infection. Herpes 2008;15:28-32.
3. Strenger V, Urban C. Chromosomal integration of the HHV-6 genome as a possible cause of persistent HHV-6 detection in a patient with langerhans cell histiocytosis. Pathol Oncol Res 2010;16:125-6.
4. Nacheva EP, Ward KN, Brazma D, et al. Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites. J Med Virol 2008;80:1952-8.
5. Strenger V, Schwinger W, Zenz W, et al. Viral antigen expression in individuals with chromosomally integrated HHV-6. 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki 2009.