Estrogen receptor α and β expressions in hypothalamus-pituitary- ovary axis in rats exposed lactationally to soy isoflavones and bisphenol A

Biomedical and Environmental Sciences

Volumn 23, Issue 5, 2010, Pages 357-362

  Yu, Bo ^a   Chen, Qing Feng ^b   Liu, Zhao Ping ^a   Xu, He Fei ^c   Zhang, Xiao Peng ^a   Xiang, Qain ^a   Zhang, Wen Zhong ^a   Cui, Wen Ming ^a   Zhang, Xin ^a   Li, Ning ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b QINGDAO UNIVERSITY   (China)

^c Shandong Entry Exit Inspection and Quarantine Bureau   (China)

Author keywords

Bisphenol A; Combinatory actions; Estrogen receptors; Soy isoflavones

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ISOFLAVONE DERIVATIVE; PHENOL DERIVATIVE; PHYTOESTROGEN;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMISTRY; DOWN REGULATION; DRUG EFFECT; DRUG POTENTIATION; ENVIRONMENTAL EXPOSURE; FEMALE; HYPOTHALAMUS HYPOPHYSIS SYSTEM; ISOLATION AND PURIFICATION; LACTATION; METABOLISM; NEWBORN; ORGAN SIZE; OVARY; RAT; SEXUAL MATURATION; SOYBEAN; SPRAGUE DAWLEY RAT; UPREGULATION; UTERUS; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; DOWN-REGULATION; DRUG SYNERGISM; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS, NON-STEROIDAL; FEMALE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; ISOFLAVONES; LACTATION; MATERNAL EXPOSURE; ORGAN SIZE; OVARY; PHENOLS; PHYTOESTROGENS; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL MATURATION; SOYBEANS; UP-REGULATION; UTERUS;

ANIMALIA; RATTUS; ZEA MAYS;

EID: 78649603213     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0895-3988(10)60076-1     Document Type: Article

References (16)

1. AA Franke, LJ Custer Daidzein and genistein concentrations in human milk after soy consumption Clin Chem 42 1996 955 964
2. Z Liu, X Zhang, L Li Effects of lactational exposure to soy isoflavones on reproductive system in neonate female rats Basic Clin Pharmacol Toxicol 102 2008 317 324
3. EU Updated European Risk Assessment Report on 4, 4′- isopropylidenediphenol (Bisphenol A). EINECS Number: 201-245-8 see also http://ecb.jrc.it/documents/Existing-Chemicals/RISK-ASSESSMENT/ADDENDUM/ bisphenola-add-325.pdf 2008
4. K Miyamoto, M Kotake Estimation of daily bisphenol A intake of Japanese individuals with emphasis on uncertainty and variability Environ Sci 13 2006 15 29
5. NTP-CERHR Expert panel report on the reproductive and developmental toxicity of bisphenol A. National Toxicology Program, U S. Department of Health and Human Services see also http://cerhr.niehs.nih.gov/chemicals/bisphenol/ BPAFinalEPVF112607.pdf 2007
6. E Silva, N Rajapakse, A Kortenkamp Something for "nothing" - eight weak estrogenic chemicals combined at concentrations below NOEC's produce significant mixture effects Environ Sci Technol 36 2002 1751 1756
7. S Schmidt, GH Degen, J Seibel Hormonal activity of combinations of genistein, bisphenol A and 17beta-estradiol in the female Wistar rat Arch Toxicol 80 2006 839 845
8. H Tinwell, J Ashby Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens Environ Health Perspect 112 2004 575 582
9. M Casanova, L You, KW Gaido Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro Toxicol Sci 51 1999 236 244
10. X Zhang, L Li, Z Liu Study on the adverse effects of soy isoflavones on reproductive system in female rats when exposed in different development stages Chinese Journal of Food Hygiene 18 2006 536 541
11. MG Wade, A Lee, A McMahon The influence of dietary isoflavone on the uterotrophic response in juvenile rats Food Chem Toxicol 41 2003 1517 1525
12. BS Katzenellenbogen, I Choi, R Delage-Mourroux Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology J Steroid Biochem Mol Biol 74 2000 279 285
13. L Monje, J Varayoud, EH Luque Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor alpha transcripts with alternative 5′-untranslated regions in the female rat preoptic area J Endocrinol 194 2007 201 212
14. K Kawai, S Murakami, E Senba Changes in estrogen receptors alpha and beta expression in the brain of mice exposed prenatally to bisphenol A Regul Toxicol Pharmacol 47 2007 166 170
15. GH Degen, P Janning, P Diel Estrogenic isoflavones in rodent diets Toxicol Lett 128 2002 145 157
16. Commission European, Scientific Committee on Food Opinion of the Scientific Committee on Food on Bisphenol A. SCF/CS/PM3936 Final see also http://www.europa.eu.int/comm/food/fS/sc/scf/index-en.html 2002