Bradykinin-induced lung inflammation and bronchoconstriction: Role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity

Journal of Pharmacology and Experimental Therapeutics

Volumn 335, Issue 3, 2010, Pages 681-692

  Broadley, Kenneth J ^a   Blair, Alan E ^a   Kidd, Emma J ^a   Bugert, Joachim J ^b   Ford, William R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; CAPTOPRIL; ICATIBANT; KALLIKREIN INHIBITOR; MEN 16132; OVALBUMIN; PHOSPHORAMIDON; UNCLASSIFIED DRUG; VA 999024;

AIRWAY DYNAMICS; AIRWAY HYPERREACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; ENZYMATIC DEGRADATION; GUINEA PIG; INFLAMMATORY CELL; MALE; NONHUMAN; PARAINFLUENZA VIRUS 3; PLETHYSMOGRAPHY; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; BRADYKININ; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOCONSTRICTION; CAPTOPRIL; CELL COUNT; GLYCOPEPTIDES; GUINEA PIGS; HISTAMINE; MALE; ORNITHINE; OVALBUMIN; PARAINFLUENZA VIRUS 3, HUMAN; PEPTIDES; PLETHYSMOGRAPHY, WHOLE BODY; PNEUMONIA; PROTEASE INHIBITORS; RECEPTOR, BRADYKININ B2; RESPIROVIRUS INFECTIONS; SULFONAMIDES; TISSUE KALLIKREINS;

EID: 78649593703     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.171876     Document Type: Article

References (40)

1. Baraniuk JN, Ohkubo K, Kwon OJ, Mak J, Ali M, Davies R, Twort C, Kaliner M, Letarte M, and Barnes PJ (1995) Localization of neutral endopeptidase (NEP) mRNA in human bronchi. Eur Respir J 8:1458-1464.
2. Berman AR, Togias AG, Skloot G, and Proud D (1995) Allergen-induced hyperresonsiveness to bradykinin is more pronounced than that to methacholine. J Appl Physiol 78:1844-1852.
3. Bryborn M, Adner M, and Cardell LO (2004) Interleukin-4 increases murine airway responses to kinins via up-regulation of bradykinin B1-receptors and altered signalling along mitogen-activated protein kinase pathways. Clin Exp Allergy 34:1291-1298.
4. Chodimella V, Skidgel RA, Krowiak EJ, and Murlas CG (1991) Lung peptidases, including carboxypeptidase, modulate airway reactivity to intravenous bradykinin. Am Rev Respir Dis 144:869-874.
5. Christiansen SC, Eddleston J, Woessner KM, Chambers SS, Ye R, Pan ZK, and Zuraw BL (2002) Up-regulation of functional kinin B1 receptors in allergic airway inflammation. J Immunol 169:2054-2060.
6. Christiansen SC, Proud D, Sarnoff RB, Juergens U, Cochrane CG, and Zuraw BL (1992) Elevation of tissue kallikrein and kinin in the airways of asthmatic subjects after endobronchial allergen challenge. Am Rev Respir Dis 145:900-905.
7. 2 receptor. In vitro pharmacology and molecular characterization. Eur J Pharmacol 528:7-16.
8. Cushley MJ, Tattersfield AE, and Holgate ST (1983) Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 15:161-165.
9. 9]BK: influence of enalaprilat. Am J Physiol Heart Circ Physiol 270:H1340-H1347.
10. Dusser DJ, Nadel JA, Sekizawa K, Graf PD, and Borson DB (1988a) Neutral endopeptidase and angiotensin converting enzyme inhibitors potentiate kinin-induced contraction of ferret trachea. J Pharmacol Exp Ther 244:531-536.
11. Dusser DJ, Umeno E, Graf PD, Djokic T, Borson DB, and Nadel JA (1988b) Airway neutral endopeptidase-like enzyme modulates tachykinin-induced bronchoconstriction in vivo. J Appl Physiol 65:2585-2591.
12. Ellis KM and Fozard JR (2002) Species differences in bradykinin receptor-mediated responses of the airways. Auton Autacoid Pharmacol 22:3-16.
13. Ellis KM, Cannet C, Mazzoni L, and Fozard JR (2004) Airway hyperresponsiveness to bradykinin induced by allergen challenge in actively sensitised Brown Norway rats. Naunyn-Schmiedebergs Arch Pharmacol 369:166-178.
14. Evans DM, Jones DM, Pitt GR, Ashworth D, De Clerck F, Verheyen F, and Szelke M (1996) Synthetic inhibitors of human tissue kallikrein. Immunopharmacology 32:117-118.
15. Folkerts G, Vlieger JW, de Vries A, Faas S, van Der Linde H, Engels F, de Jong JC, Verheyen FA, Van Heuven-Nolsen D, and Nijkamp FP (2000) Virus and bradykinin-induced airway hyperresponsiveness in guinea pigs. Am J Respir Crit Care Med 161:1666-1671.
16. Huang TJ, Haddad EB, Fox AJ, Salmon M, Jones C, Burgess G, and Chung KF (1999) Contribution of bradykinin B(1) and B(2) receptors in allergen-induced bronchial hyperresponsiveness. Am J Respir Crit Care Med 160:1717-1723.
17. Ichinose M and Barnes PJ (1990a) Bradykinin-induced airway microvascular leakage and bronchoconstriction are mediated via a bradykinin B2 receptor. Am Rev Respir Dis 142:1104-1107.
18. Ichinose M and Barnes PJ (1990b) The effect of peptidase inhibitors on bradykinin-nduced bronchoconstriction in guinea pigs in vivo. Br J Pharmacol 101:77-80.
19. Ichinose M, Belvisi MG, and Barnes PJ (1990) Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanisms. J Pharmacol Exp Ther 253:594-599.
20. Koyama S, Rennard SI, and Robbins RA (1995) Bradykinin stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity. Am J Physiol Lung Cell Mol Physiol 269:L38-L44.
21. Leeb-Lundberg LM, Marceau F, Müller-Esterl W, Pettibone DJ, and Zuraw BL (2005) International Union of Pharmacology. XLV. Classification of kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev 57:27-77.
22. Miura M, Belvisi MG, and Barnes PJ (1994) Modulation of nonadrenergic noncholinergic neural bronchoconstriction by bradykinin in anaesthetized guinea pigs in vivo. J Pharmacol Exp Ther 268:482-486.
23. Nagae A, Abe M, Becker RP, Deddish PA, Skidgel RA, and Erdös EG (1993) High concentration of carboxypeptidase M in lungs: presence of the enzyme in alveolar type I cells. Am J Respir Cell Mol Biol 9:221-229.
24. 9]bradykinin in normal and asthmatic subjects. Am Rev Respir Dis 142:1367-1371.
25. Polosa R, Rajakulasingam K, Prosperini G, Milazzo LV, Santonocito G, and Holgate ST (1993) Cross-tachyphylactic airway response to imhaled bradykinin, kallidin and [desArg9]-bradykinin in asthma subjects. Eur Respir J 6:687-693.
26. Proud D and Kaplan AP (1988) Kinin formation: mechanisms and role in inflammatory disorders. Annu Rev Immunol 6:49-83.
27. Reed LJ and Muench H (1938) A simple method of estimating fifty percent end points. Am J Hygiene 27:493-497.
28. Regoli D, Nsa Allogho S, Rizzi A, and Gobeil FJ (1998) Bradykinin receptors and their antagonists. Eur J Pharmacol 348:1-10.
29. Ricciardolo FL, Nadel JA, Yoshihara S, Geppetti P, and Yoishihara S (1994) Evidence for reduction of bradykinin-induced bronchoconstriction in guinea pigs by release of nitric oxide. Br J Pharmacol 113:1147-1152.
30. Sakamoto T, Barnes PJ, and Chung KF (1996) Lack of a role for bradykinin in allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig. Inflamm Res 45:123-126. (Pubitemid 26097455)
31. Sakamoto T, Sun J, Barnes PJ, and Chung KF (1994) Effect of a bradykinin receptor antagonist, HOE 140, against bradykinin- and vagal stimulation-induced airway responses in the guinea pig. Eur J Pharmacol 251:137-142.
32. Sato E, Koyama S, Nomura H, Kubo K, and Sekiguchi M (1996) Bradykinin stimulates alveolar macrophages to release neutrophil, monocyte, and eosinophil chemotactic activity. J Immunol 157:3122-3129.
33. Sato E, Nelson DK, Koyama S, Hoyt JC, and Robbins RA (2000) Bradykinin stimulates eotaxin production by a human lung fibroblast cell line. J Allergy Clin Immunol 106:117-123.
34. Smith N and Broadley KJ (2007) Optimization of the sensitisation conditions for an ovalbumin challenge model of asthma. Int Immunopharmacol 7:183-190.
35. Smith N and Broadley KJ (2008) Adenosine receptors subtypes involved in the airways responses to 5′-AMP inhalation of sensitized guinea pigs. Clin Exp Allergy 38:1536-1547.
36. Toward TJ and Broadley KJ (2004) Early and late bronchoconstrictions, airway hyper-reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram. Clin Exp Allergy 34:91-102.
37. Toward TJ, Johnson FJ, Boult JE, and Maillard JY (2005) Airway function and reactivity, leukocyte influx and nitric oxide after inoculation with parainfluenza-3 virus: effects of dexamethasone or rolipram. Int Immunopharmacol 5:771-782.
38. Tramontana M, Lecci A, Meini S, Montserrat X, Pascual J, Giuliani S, Quartara L, and Maggi CA (2001) Differences between peptide and nonpeptide B(2) bradykinin receptor antagonists in blocking bronchoconstriction and hypotension induced by bradykinin in anaesthetized guinea pigs. J Pharmacol Exp Ther 296:1051-1057.
39. Valenti C, Cialdai C, Giuliani S, Lecci A, Tramontana M, Meini S, Quartara L, and Maggi CA (2005) MEN16132, a novel potent and selective nonpeptide kinin B2 receptor antagonist: in vivo activity on bradykinin-induced bronchoconstriction and nasal mucosa microvascular leakage in anesthetized guinea pigs. J Pharmacol Exp Ther 315:616-623.
40. Wirth KJ, Gehring D, and Schölkens BA (1993) Effects of Hoe 140 on bradykinin-induced bronchoconstriction in anaesthetized guinea pigs. Am Rev Respir Dis 148:702-706.