Experimental orthodontic tooth movement and extensive root resorption: Periodontal and pulpal changes

European Journal of Oral Sciences

Volumn 118, Issue 6, 2010, Pages 596-603

  Tripuwabhrut, Polbhat ^a   Brudvik, Pongsri ^a   Fristad, Inge ^a   Rethnam, Sivakami ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

Blood vessels; Immune cells; Inflammation; Nerve fibres; Periodontal ligament

Indexed keywords

CD68 PROTEIN, RAT; DIFFERENTIATION ANTIGEN; HLA ANTIGEN CLASS 2; LAMININ; LEUKOCYTE ANTIGEN; LEUKOSIALIN; PGP9.5 PROTEIN, RAT; UBIQUITIN THIOLESTERASE;

ANIMAL; ARTICLE; COMPARATIVE STUDY; IMMUNOLOGY; MACROPHAGE; MALE; MICROVASCULATURE; MOLAR TOOTH; MONONUCLEAR CELL; NERVE FIBER; PATHOLOGY; PERIODONTAL DISEASE; PERIODONTAL LIGAMENT; PERIODONTITIS; PRESSURE; PULPITIS; RAT; SPRAGUE DAWLEY RAT; T LYMPHOCYTE; TOOTH DISEASE; TOOTH PULP;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD43; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; DENTAL PULP; HISTOCOMPATIBILITY ANTIGENS CLASS II; LAMININ; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MALE; MICROVESSELS; MOLAR; NERVE FIBERS; PERIODONTAL LIGAMENT; PERIODONTITIS; PRESSURE; PULPITIS; RATS; RATS, SPRAGUE-DAWLEY; ROOT RESORPTION; T-LYMPHOCYTES; TOOTH MOVEMENT; UBIQUITIN THIOLESTERASE;

EID: 78649553821     PISSN: 09098836     EISSN: 16000722     Source Type: Journal    
DOI: 10.1111/j.1600-0722.2010.00786.x     Document Type: Article

References (49)

1. Jontell M, Bergenholtz G, Scheynius A, Ambrose W. Dendritic cells and macrophages expressing class II antigens in the normal rat incisor pulp. J Dent Res 1988; 67: 1263-1266.
2. Jontell M, Gunraj MN, Bergenholtz G. Immunocompetent cells in the normal dental pulp. J Dent Res 1987; 66: 1149-1153.
3. Hahn CL, Falkler WA Jr, Siegel MA. A study of T and B cells in pulpal pathosis. J Endod 1989; 15: 20-26.
4. Okiji T, Kawashima N, Kosaka T, Matsumoto A, Kobayashi C, Suda H. An immunohistochemical study of the distribution of immunocompetent cells, especially macrophages and Ia antigen-expressing cells of heterogeneous populations, in normal rat molar pulp. J Dent Res 1992; 71: 1196-1202.
5. Bergenholtz G, Nagaoka S, Jontell M. Class II antigen expressing cells in experimentally induced pulpitis. Int Endod J 1991; 24: 8-14.
6. Fristad I, Heyeraas KJ, Kvinnsland I. Nerve fibres and cells immunoreactive to neurochemical markers in developing rat molars and supporting tissues. Arch Oral Biol 1994; 39: 633-646.
7. Fristad I, Bletsa A, Byers M. Inflammatory nerve responses in the dental pulp. Endod Top 2010; 17: 12-41.
8. Kim S, Heyeraas KJ, Haug SR. Structure and function of the dentin-pulp complex. In: Baumgartner IB, ed. Ingle's endodontics 6. Hamilton: BC Decker Inc., 2008; 118-150.
9. Vandevska-Radunovic V, Kvinnsland S, Kvinnsland IH. Effect of experimental tooth movement on nerve fibres immunoreactive to calcitonin gene-related peptide, protein gene product 9.5, and blood vessel density and distribution in rats. Eur J Orthod 1997; 19: 517-529.
10. Heyeraas KJ, Kvinnsland I, Byers MR, Jacobsen EB. Nerve fibers immunoreactive to protein gene product 9.5, calcitonin gene-related peptide, substance P, and neuropeptide Y in the dental pulp, periodontal ligament, and gingiva in cats. Acta Odontol Scand 1993; 51: 207-221.
11. Tadokoro O, Vandevska-Randunovic V, Inoue K. Epithelial cell rests of Malassez and OX6-immunopositive cells in the periodontal ligament of rat molars: a light and transmission electron microscope study. Anat Rec (Hoboken) 2008; 291: 242-253.
12. Haug SR, Brudvik P, Fristad I, Heyeraas KJ. Sympathectomy causes increased root resorption after orthodontic tooth movement in rats: immunohistochemical study. Cell Tissue Res 2003; 313: 167-175.
13. Vandevska-Radunovic V, Kvinnsland IH, Kvinnsland S, Jonsson R. Immunocompetent cells in rat periodontal ligament and their recruitment incident to experimental orthodontic tooth movement. Eur J Oral Sci 1997; 105: 36-44.
14. Brudvik P, Rygh P. Non-clast cells start orthodontic root resorption in the periphery of hyalinized zones. Eur J Orthod 1993; 15: 467-480.
15. Brudvik P, Rygh P. The initial phase of orthodontic root resorption incident to local compression of the periodontal ligament. Eur J Orthod 1993; 15: 249-263.
16. Nakamura K, Sahara N, Deguchi T. Temporal changes in the distribution and number of macrophage-lineage cells in the periodontal membrane of the rat molar in response to experimental tooth movement. Arch Oral Biol 2001; 46: 593-607.
17. Kvinnsland S, Heyeraas K, Ofjord ES. Effect of experimental tooth movement on periodontal and pulpal blood flow. Eur J Orthod 1989; 11: 200-205.
18. McDonald F, Pitt Ford TR. Blood flow changes in permanent maxillary canines during retraction. Eur J Orthod 1994; 16: 1-9.
19. Santamaria M, Jr, Milagres D, Stuani AS, Stuani MB, Ruellas AC. Initial changes in pulpal microvasculature during orthodontic tooth movement: a stereological study. Eur J Orthod 2006; 28: 217-220.
20. Vandevska-Radunovic V. Neural modulation of inflammatory reactions in dental tissues incident to orthodontic tooth movement. A review of the literature. Eur J Orthod 1999; 21: 231-247.
21. Alhashimi N, Frithiof L, Brudvik P, Bakhiet M. Orthodontic tooth movement and de novo synthesis of proinflammatory cytokines. Am J Orthod Dentofacial Orthop 2001; 119: 307-312.
22. Bletsa A, Berggreen E, Brudvik P. Interleukin-1alpha and tumor necrosis factor-alpha expression during the early phases of orthodontic tooth movement in rats. Eur J Oral Sci 2006; 114: 423-429.
23. Santamaria M Jr, Milagres D, Iyomasa MM, Stuani MB, Ruellas AC. Initial pulp changes during orthodontic movement: histomorphological evaluation. Braz Dent J 2007; 18: 34-39.
24. Perinetti G, Varvara G, Festa F, Esposito P. Aspartate aminotransferase activity in pulp of orthodontically treated teeth. Am J Orthod Dentofacial Orthop 2004; 125: 88-92.
25. Rana MW, Pothisiri V, Killiany DM, Xu XM. Detection of apoptosis during orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop 2001; 119: 516-521.
26. Unsterseher RE, Nieberg LG, Weimer AD, Dyer JK. The response of human pulpal tissue after orthodontic force application. Am J Orthod Dentofacial Orthop 1987; 92: 220-224.
27. Mostafa YA, Iskander KG, El-Mangoury NH. Iatrogenic pulpal reactions to orthodontic extrusion. Am J Orthod Dentofacial Orthop 1991; 99: 30-34.
28. Brudvik P, Rygh P. Multi-nucleated cells remove the main hyalinized tissue and start resorption of adjacent root surfaces. Eur J Orthod 1994; 16: 265-273.
29. Brudvik P, Rygh P. Root resorption beneath the main hyalinized zone. Eur J Orthod 1994; 16: 249-263.
30. Mavragani M, Brudvik P, Selvig KA. Orthodontically induced root and alveolar bone resorption: inhibitory effect of systemic doxycycline administration in rats. Eur J Orthod 2005; 27: 215-225.
31. Brudvik P, Rygh P. The repair of orthodontic root resorption: an ultrastructural study. Eur J Orthod 1995; 17: 189-198.
32. Brudvik P, Rygh P. Transition and determinants of orthodontic root resorption-repair sequence. Eur J Orthod 1995; 17: 177-188.
33. Sasakura H, Yoshida T, Murayama S, Hanada K, Nakajima T. Root resorption of upper permanent incisor caused by impacted canine. An analysis of 23 cases. Int J Oral Surg 1984; 13: 299-306.
34. Savage RR, Kokich VG Sr. Restoration and retention of maxillary anteriors with severe root resorption. J Am Dent Assoc 2002; 133: 67-71.
35. Doran JF, Jackson P, Kynoch PA, Thompson RJ. Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. J Neurochem 1983; 40: 1542-1547.
36. Ngan P, Kess B, Wilson S. Perception of discomfort by patients undergoing orthodontic treatment. Am J Orthod Dentofacial Orthop 1989; 96: 47-53.
37. Wilson S, Ngan P, Kess B. Time course of the discomfort in young patients undergoing orthodontic treatment. Pediatr Dent 1989; 11: 107-110.
38. Rygh P, Bowling K, Hovlandsdal L, Williams S. Activation of the vascular system: a main mediator of periodontal fiber remodeling in orthodontic tooth movement. Am J Orthod 1986; 89: 453-468.
39. Ren Y, Kuijpers-Jagtman AM, Maltha JC. Immunohistochemical evaluation of osteoclast recruitment during experimental tooth movement in young and adult rats. Arch Oral Biol 2005; 50: 1032-1039.
40. Suzuki N, Okiji T, Suda H. Enhanced expression of activation-associated molecules on macrophages of heterogeneous populations in expanding periapical lesions in rat molars. Arch Oral Biol 1999; 44: 67-79.
41. Fuss Z, Tsesis I, Lin S. Root resorption-diagnosis, classification and treatment choices based on stimulation factors. Dent Traumatol 2003; 19: 175-182.
42. Brezniak N, Wasserstein A. Orthodontically induced inflammatory root resorption. Part II: The clinical aspects. Angle Orthod 2002; 72: 180-184.
43. Gholston LR, Mattison GD. An endodontic-orthodontic technique for esthetic stabilization of externally resorbed teeth. Am J Orthod 1983; 83: 435-440.
44. Dijkstra CD, Dopp EA, Joling P, Kraal G. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 1985; 54: 589-599.
45. Jager A, Radlanski RJ, Gotz W. Demonstration of cells of the mononuclear phagocyte lineage in the periodontium following experimental tooth movement in the rat. An immunohistochemical study using monoclonal antibodies ED1 und ED2 on paraffin-embedded tissues. Histochemistry 1993; 100: 161-166.
46. Sminia T, Dijkstra CD. The origin of osteoclasts: an immunohistochemical study on macrophages and osteoclasts in embryonic rat bone. Calcif Tissue Int 1986; 39: 263-266.
47. Fukumoto T, McMaster WR, Williams AF. Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus. Eur J Immunol 1982; 12: 237-243.
48. McMaster WR, Williams AF. Identification of Ia glycoproteins in rat thymus and purification from rat spleen. Eur J Immunol 1979; 9: 426-433.
49. Barclay AN. The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology 1981; 42: 593-600.