Unmasking tuberculosis-associated immune reconstitution inflammatory syndrome in HIV-1 infection after antiretroviral therapy

Asian Pacific Journal of Allergy and Immunology

Volumn 28, Issue 2-3, 2010, Pages 206-209

  Pornprasert, Sakorn ^a   Leechanachai, Pranee ^a   Klinbuayaem, Virat ^b   Leenasirimakul, Prattana ^c   Promping, Channat ^c   Inta, Prasit ^b   Ajhan, Siraporn ^b  

^a CHIANG MAI UNIVERSITY   (Thailand)

^b Sanpatong Hospital   (Thailand)

^c NAKORNPING HOSPITAL   (Thailand)

Author keywords

Antiretrovirals; Cytokines; HIV; Immune reconstitution inflammatory syndrome; Mycobacterium tuberculosis

Indexed keywords

ETHAMBUTOL; GAMMA INTERFERON; INTERLEUKIN 10; ISONIAZID; LAMIVUDINE; NEVIRAPINE; PREDNISOLONE; PYRAZINAMIDE; RIFAMPICIN; TUMOR NECROSIS FACTOR ALPHA; ZIDOVUDINE;

ACID FAST BACTERIUM; ADULT; ANTIVIRAL THERAPY; ARTICLE; CASE REPORT; CD4 LYMPHOCYTE COUNT; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; INTESTINE TUBERCULOSIS; MESENTERY LYMPH NODE; PROTEIN BLOOD LEVEL; TREATMENT OUTCOME; TUBERCULOSIS; TUBERCULOUS LYMPHADENITIS; TUBERCULOUS PERITONITIS;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; ANTITUBERCULAR AGENTS; CYTOKINES; DIAGNOSIS, DIFFERENTIAL; DISEASE-FREE SURVIVAL; DYSPNEA; FEMALE; FEVER; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; INTESTINES; MYCOBACTERIUM TUBERCULOSIS; PERITONITIS, TUBERCULOUS; TH1-TH2 BALANCE;

EID: 78649522582     PISSN: 0125877X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. French MA, Lenzo N, John M. Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy. HIV Med 2000; 1: 107-15.
2. Shelburne SA, Hamill RJ, Montes M. The immune reconstitution inflammatory syndrome. AIDS Rev 2003; 5: 67-79.
3. Stoll M, Heiken H, Weber K, Hundt M, Behrens G, Schmidt RE. Immune reconstituted inflammatory syndrome. Pitfalls of antiretroviral therapy. MMW Fortschr Med 2003; 145: 42-7.
4. Meintjes G, Lawn SD, Scano F, et al. Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings. Lancet Infect Dis 2008; 8: 516-23.
5. Lawn SD, Bekker LG, Miller RF. Immune reconstitution disease associated with mycobacterial infections in HIV-infected individuals receiving antiretrovirals. Lancet Infect Dis 2005; 5: 361-73.
6. Shelburne SA 3rd, Hamill RJ, Rodriguez-Barradas MC, et al. Immune reconstitution inflammatory syndrome: emergence of a unique syndrome during highly active antiretroviral therapy. Medicine (Baltimore) 2002; 81: 213-27.
7. Navas E, Martin-Davila P, Moreno L, et al. Paradoxical reactions of tuberculosis in patients with the acquired immunodeficiency syndrome who are treated with highly active antiretroviral therapy. Arch Intern Med 2002; 162: 97-9.
8. Manosuthi W, Kiertiburanakul S, Phoorisri T, Sungkanuparph S. Immune reconstitution inflammatory syndrome of tuberculosis among HIV-infected patients receiving antituberculous and antiretroviral therapy. J Infect 2006; 53: 357-63.
9. Schiffer JT, Sterling TR. Timing of antiretroviral therapy initiation in tuberculosis patients with AIDS: a decision analysis. J Acquir Immune Defic Syndr 2007; 44: 229-34.
10. Schluger NW, Rom WN. The host immune response to tuberculosis. Am J Respir Crit Care Med 1998; 157: 679-91.
11. Giovannetti A, Pierdominici M, Mazzetta F, et al. T cell responses to highly active antiretroviral therapy defined by chemokine receptors expression, cytokine production, T cell receptor repertoire and anti-HIV T-lymphocyte activity. Clin Exp Immunol 2001; 124: 21-31.
12. Li Q, Schacker T, Carlis J, Beilman G, Nguyen P, Haase AT. Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy. J Infect Dis 2004; 189: 572-82.
13. Westby M, Marriott JB, Guckian M, Cookson S, Hay P, Dalgleish AG. Abnormal intracellular IL-2 and interferon-gamma (IFN-gamma) production as HIV-1-associated markers of immune dysfunction. Clin Exp Immunol 1998; 111; 257-63.
14. Lim A, D'Orsogna L, Price P, French MA. Imbalanced effector and regulatory cytokine responses may underlie mycobacterial immune restoration disease. AIDS Res Ther 2008; 5: 9.
15. Clerici M, Shearer GM. A TH1-TH2 switch is a critical step in the etiology of HIV infection. Immunol Today 1993; 14: 107-11.
16. Weissman D, Poli G, Fauci AS. Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus. AIDS Res Hum Retroviruses 1994; 10: 1199-206.
17. Bonham S, Meya DB, Bohjanen PR, Boulware DR. Biomarkers of HIV Immune Reconstitution Inflammatory Syndrome. Biomark Med 2008; 2: 349-61.
18. Seddiki N, Sasson SC, Santner-Nanan B, et al. Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease. Eur J Immunol 2009; 39: 391-403.