Lentiviral vector-mediated knockdown of the neuroglycan 2 proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar

Journal of Gene Medicine

Volumn 12, Issue 11, 2010, Pages 863-872

  Donnelly, Eleanor M ^a   Strappe, Padraig M ^b   McGinley, Lisa M ^a   Madigan, Nicolas N ^a,c   Geurts, Elizabeth ^a   Rooney, Gemma E ^c   Windebank, Anthony J ^c   Fraher, John ^d   Dockery, Peter ^e   O'Brien, Timothy ^a   McMahon, Siobhan S ^a,e  

^a UNIVERSITY HOSPITAL GALWAY   (Ireland)

^b CHARLES STURT UNIVERSITY   (Australia)

^c MAYO CLINIC   (United States)

^d UNIVERSITY COLLEGE CORK   (Ireland)

^e NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Glial scar; Lentiviral vector; Neu7 astrocytes; Neurotrophin 3; NG2; Spinal cord injury

Indexed keywords

LENTIVIRUS VECTOR; NEUROGLYCAN 2; NEUROTROPHIN 3; PROTEOGLYCAN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; COCULTURE; CONTROLLED STUDY; ELECTROPORATION; GENE EXPRESSION; GENE TARGETING; MOLECULAR CLONING; NERVE CELL CULTURE; NERVE FIBER GROWTH; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; SPINAL GANGLION;

ANIMALS; ASTROCYTES; AXONS; CELL LINE; CELLS, CULTURED; COCULTURE TECHNIQUES; GANGLIA, SPINAL; GENE KNOCKDOWN TECHNIQUES; GENETIC VECTORS; LENTIVIRUS; NERVE REGENERATION; NEURITES; NEURONS; NEUROTROPHIN 3; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SPINAL CORD INJURIES;

RATTUS;

EID: 78649495402     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1509     Document Type: Article

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