Bold claims for optogenetics

Nature

Volumn 468, Issue 7323, 2010, Pages

  Logothetis, Nikos K ^a,b  

^a MAX PLANCK INSTITUTE FOR BIOLOGICAL CYBERNETICS   (Germany)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; RHODOPSIN;

ANTIDROMIC STIMULATION; BLOOD OXYGENATION; BRAIN MAPPING; BRAIN METABOLISM; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETICS; HUMAN; MOTOR CORTEX; NERVE CELL STIMULATION; NERVE PROJECTION; NOTE; OPTOGENETICS; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SPIKE; THALAMUS NUCLEUS; VISUAL CORTEX;

ANIMALS; MAGNETIC RESONANCE IMAGING; MOTOR CORTEX; NEURONS; OXYGEN; PHOTIC STIMULATION; PYRAMIDAL CELLS; RATS; RESEARCH; RHODOPSIN; SIGNAL TRANSDUCTION;

EID: 78649485961     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09532     Document Type: Note

References (15)

1. Lee, J. H. et al. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature 465, 788-792 (2010).
2. Douglas, R. J. & Martin, K. A. C. Recurrent neuronal circuits in the neocortex. Curr. Biol. 17, R496-R500 (2007).
3. Markram, H. et al. Interneurons of the neocortical inhibitory system. Nature Rev. Neurosci. 5, 793-807 (2004).
4. Somogyi, P., Tamas, G., Lujan, R. & Buhl, E. H. Salient features of synaptic organisation in the cerebral cortex. Brain Res. Brain Res. Rev. 26, 113-135 (1998).
5. Douglas, R. J., Martin, K. A. & Whitteridge, D. An intracellular analysis of the visual responses of neurones in cat visual cortex. J. Physiol. 440, 659-696 (1991).
6. Keller, A. Intrinsic synaptic organization of the motor cortex. Cereb. Cortex 3, 430-441 (1993).
7. Sohal,V.S.,Zhang, F., Yizhar,O.&Deisseroth,K. Parvalbuminneuronsandgamma rhythms enhance cortical circuit performance. Nature 459, 698-702 (2009).
8. Cardin, J. A. et al. Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature 459, 663-667 (2009).
9. Han, X. et al. Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron 62, 191-198 (2009).
10. Jueptner, M. & Weiller, C. Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI. Neuroimage 2, 148-156 (1995).
11. Phillips,C.G.Actions ofantidromic pyramidal volleyson single Betz cellsinthe cat. Q. J. Exp. Physiol. Cogn. Med. Sci. 44, 1-25 (1959).
12. Ferster, D. & Lindstrom, S. Synaptic excitation of neurones in area 17 of the cat by intracortical axon collaterals of cortico-geniculate cells. J. Physiol. 367, 233-252 (1985).
13. Okun, M. & Lampl, I. Instantaneous correlation of excitation and inhibition during ongoing and sensory-evoked activities. Nature Neurosci. 11, 535-537 (2008).
14. Logothetis, N. K. & Wandell, B. A. Interpreting the BOLD signal. Annu. Rev. Physiol. 66, 735-769 (2004).
15. Logothetis, N. K. What we can do and what we cannot do with fMRI. Nature 453, 869-878 (2008).