Median lethal dose, antimalarial activity, phytochemical screening and radical scavenging of methanolic languas galanga rhizome extract

Molecules

Volumn 15, Issue 11, 2010, Pages 8366-8376

  Al Adhroey, Abdulelah H ^a   Nor, Zurainee M ^a   Al Mekhlafi, Hesham M ^a   Mahmud, Rohela ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Antimalarial activity; Languas galanga; Methanolic extract

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ANTIMALARIAL AGENT; BIPHENYL DERIVATIVE; METHANOL; PICRIC ACID; PLANT EXTRACT;

ALPINIA; ANIMAL; ARTICLE; CHEMISTRY; FEMALE; INSTITUTE FOR CANCER RESEARCH MOUSE; LD 50; MALARIA; MALE; MOUSE; PLASMODIUM BERGHEI; RHIZOME;

ALPINIA; ANIMALS; ANTIMALARIALS; BIPHENYL COMPOUNDS; FEMALE; LETHAL DOSE 50; MALARIA; MALE; METHANOL; MICE; MICE, INBRED ICR; PICRATES; PLANT EXTRACTS; PLASMODIUM BERGHEI; RHIZOME;

EID: 78649478919     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15118366     Document Type: Article

References (43)

1. Chevallier, A. The Encyclopedia of Medicinal Plants; Dorling Kindersley Limited: London, UK, 1996.
2. Burkill, I.H. A Dictionary of the Economic Products of the Malay Peninsula; Crown Agents for the Colonies: London, UK, 1966; Volume II, pp. 1327-1332.
3. Latha, C.; Shriram, D.; Jahagirdar, S.; Dhakephalkar, P.; Rojatkar, S. Antiplasmid activity of 1′- acetoxychavicol acetate from Alpinia galanga against multi-drug resistant bacteria. J. Ethnopharmacol. 2009, 25, 522-525.
4. Jantan, I.B.; Ahmad, F.B.; Ahmad, A.S. Constituents of the rhizome and seed oils of greater galangal Alpinia galanga (L) from Malaysia. J. Essent. Oil Res. 2004, 16, 174-176.
5. De Pooter, H.L.; Omar, M.N.; Coolsaet, B.A.; Schamp, N.M. The essential oil of greater galangal (Alpinia galanga) from Malaysia. Phytochemistry 1985, 24, 93-96.
6. Scheffer, J.J.C.; Gani, A.; Baerheim-Svenden, A. Monoterpenes in the essential rhizome oil of Alpinia galanga. Sci Pharm. 1981, 49, 337-346.
7. Mori, H.; Kubota, K.; Kobayashi, A. Potent aroma components of rhizomes of Alpinia galanga Willd. L. Nippon Shokuhin Kagaku Kogaku Kaishi 1995, 42, 989-995.
8. Charles, D.J.; Simon, J.E.; Singh, N.K. The essential oil of Alpinia Galanaga Willd. J. Essent. Oil Res. 1999, 11, 719-723.
9. Itokawa, H.; Morita, H.; Sumitomo, T.; Totsuka, N.; Takeya, K. Antitumour principles from Alpinia galanga. Planta Med. 1987, 53, 32-33.
10. Matsuda, H.; Morikawa, T.; Managi, H.; Yoshikawa, M. Antiallergic principles from Alpinia galanga: Structural requirements of phenylproponoids for inhibition of degranulation and release of TNF-α and lL-4 in RBL-2H3 cells. Bioorg. Med. Chem. Lett. 2003, 13, 3197-3202.
11. Mitsui, S.; Kobayashi, S.; Nagahori, H.; Ogiso, A. Constituents from seeds of Alpinia galanga WILD and their anti-ulcer activities. Chem. Pharm. Bull. 1976, 24, 2377-2382.
12. Janssen, A.M.; Scheffer, J.J.C. Acetoxychavicol acetate, an antifungal component of Alpinia galanga. Planta Med. 1985, 6, 507-511.
13. Oonmetta-aree, J.; Suzuki, T.; Gasaluck, P.; Eumkeb, G. Antimicrobial properties and action of galangal (Alpinia galanga Linn.) on Staphylococcus aureus. LWT Food Sci. Tech. 2006, 39, 1214-1220.
14. Ye, Y.; Li, B. 1′S-1′-Acetoxychavicol acetate isolated from Alpinia galangal inhibits human immunodeficiency virus type 1 replication by blocking Rev transport. J. Gen. Virol. 2006, 87, 2047-2053.
15. Htut, Z.W. Artemisinin resistance in Plasmodium falciparum malaria. N. Engl. J. Med. 2009, 361, 1807-1808.
16. Sendagire, H.; Kyabayinze, D.; Swedberg, G.; Kironde, F. Plasmodium falciparum: Higher incidence of molecular resistance markers for sulfadoxine than for pyrimethamine in Kasangati, Uganda. Trop. Med. Int. Health 2005, 10, 537-543.
17. Saxena, S.; Pant, N.; Jain, D.C.; Bhakuni, R.S. Antimalarial agents from plant sources. Curr. Sci. 2003, 85, 1314-1329.
18. Nahoko, U. Antichagasic activities of natural products against Trypanosoma cruzi. J. Health Sci. 2009, 55, 31-39.
19. Amandeep, K.; Ranvir, S.; Sankar D.C.; Sharma, S.S.; Kamlesh, K.B.; Singh I.P. Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd. Indian J. Exp. Biol. 2010, 48, 314-322.
20. Raj, R.K. Screening of indigenous plants for anthelmintic action against human Ascaris lumbricoides: Part-II. Indian J. Physiol. Pharmacol. 1975, 19, 47-49.
21. Horn, H.J. Simplified LD50 (ED50) calculation. Biometrics 1956, 12, 312-322.
22. Rhiouani, H.; El-Hilaly, J.; Israili, Z.H.; Lyoussi, B. Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents. J. Ethnopharmacol. 2008, 118, 378-386.
23. Elufioye, T.O.; Agbedahunsi, J.M. Antimalarial activities of Tithonia diversifolia (Asteraceae) and Crossopteryx febrifuga (Rubiaceae) on mice in vivo. J. Ethnopharmacol. 2004, 93, 167-1671.
24. Ishih, A.; Suzuki, T.; Muregi, F.W.; Kachi. S.; Matsui, K.; Terada, M. Chloroquine efficacy in Plasmodium berghei NK65-infected ICR mice, with reference to the influence of initial parasite load and starting day of drug administration on the outcome of treatment. Southeast Asian J. Trop. Med. Public Health. 2006, 37, 13-17.
25. Philipson. J.D; Wright, C.W. Antiprotozoal compounds from plants sources. Planta Med. 1991, 57, 553-559.
26. Francois, G.; Passreiter, C.M.; Woerdenbag, H.J.; Looveren, M.V. Antimalarial activities and cytotoxic effects of aqueous extracts and sesquiterpene lactones from Neurolaena lobata. Planta Med. 1996, 2, 126-129.
27. Ghoshal, S.; Prasad, BN.; Lakshmi, V. Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo. J. Ethnopharmacol. 1996, 3, 167-170.
28. Asase, A.; Akwetey, G.A.; Achel, D.l.G. Ethnopharmacological use of herbal remedies for the treatment of malaria in the Dangme West District of Ghana. J. Ethnopharmacol. 2010, 129, 367-376
29. Kim, Y.C.; Kim, H.; Wataya, Y.; Sohn, D.H.; Kang, T.H.; Kim, M.S.; Kim, Y.M.; Lee, G.; Chang, J.; Park, H. Antimalarial activity of lavandulyl flavanones isolated from the roots of Sophora flavescens. Biol. Pharm. Bull. 2004, 27, 748-750.
30. Monbrison, F.; Maitrejean, M.; Latour, C.; Bugnazet, F.; Peyron, F.; Barron, D.; Picot, S. In vitro antimalarial activity of flavonoid derivatives dehydrosilybin and 8-(1;1)-DMA-kaempferide. Acta Trop. 2006, 97, 102-107.
31. Tasdemir, D.; Kaiser, D.; Brun, R.; Yardley, V.; Schmidt, T.J.; Tosun, F.; Ruedi, P. Antitrypanosomal and antileishmanial activities of flavonoids and their analogues: In vitro, in vivo, structure-activity relationship, and quantitative structure-activity relationship studies. Antimicrob. Agents Chemother. 2006, 50, 1352-1364.
32. Morikawa, T.; Ando, S.; Matsuda, H.; Kataoka, S.; Muraoka, O.; Yoshikawa, M. Inhibitors of nitric oxide production from the rhizomes of Alpinia galanga: Structures of new 8-9′ linked neolignans and sesquineolignan. Chem. Pharm. Bull. 2005, 53, 625-630.
33. Antony, P.J.; Fyfe, L.; Smith, H. Plant active components-a source for anti-parasitic agents? Trend Parasitol. 2005, 21, 462-468.
34. Däubener, W.; Hucke, C.; Seidel, K.; Hadding, U.; MacKenzie, C.R. Interleukin-1 inhibits gamma interferon-induced bacteriostasis in human uroepithelial cells. Infect. Immun. 1999, 67, 5615-5620.
35. Abdulelah, H. A.; Zurainee, M.N.; Hesham, M.A.; Rohela, M. Ethnobotanical study on some Malaysian anti-malarial plants: A community based survey. J. Ethnopharmacol. 2010, doi:10.1016/j.jep.2010.08.006.
36. Guideline for the testing of chemicals (OECD): Acute oral toxicity - Acute toxic class method. Section 423, 2001.
37. Ishih, A.; Suzuki, T.; Hasegawa, T.; Kachi. S.; Wang, H.H.; Terada, M. In vivo evaluation of combination effects of chloroquine with cepharanthin or minocycline hydrochloride against blood-induced choloquine-resistant Plasmodium berghei NK65 infections. Trop. Med. Health 2004, 32, 15-19.
38. Peters, W.; Robinson, B.L. The chemotherapy of rodent malaria XLVII: studies on pyronaridine and other Mannich base antimalarials. Ann. Trop. Med. Parasitol. 1992, 86, 455-465.
39. Saidu, K.; Onah, J.; Orisadipe, A.; Olusola, A.; Wambebe, C.; Gamaniel, K. Antiplasmodial, analgesic, and anti-inflammatory activities of the aqueous extract of Erythrina senegalensis. J. Ethnopharmacol. 2000, 71, 275-280.
40. Peters, W. Drug resistance in Plasmodium berghei. Vinke and Lips 1948. I. Chloroquine resistance. Exp. Parasitol. 1965, 17, 80-89.
41. Sofowora, A. Medicinal Plants and Traditional Medicine in Africa, 2nd ed.; Spectrum Books Limited: Ibadan, Nigeria, 1993.
42. Trease, G.E.; Evans, W.C. Pharmacognosy, 13th ed.; Bailliere Tindall: London, UK, 1989; pp. 683-684.
43. Gerhäuser, C.; Klimo, K.; Heiss, E.; Neumann, I.; Gamal-Eldeen, A.; Knauft, J.; Liu, J.U.; Sitthimonchai, S.; Frank, N. Mechanism-based in vitro screening of potential cancer chemopreventive agents. Mut. Res. 2003, 523-524, 163-172.