Solubilization properties of hydrophobic curcumin by bile salt/lipid mixed micelles

Huadong Ligong Daxue Xuebao/Journal of East China University of Science and Technology

Volumn 36, Issue 5, 2010, Pages 639-644

  Zhang, Qiong ^a   Li, Lin ^b   Wei, Dong Zhi ^a   Yang, Sheng Li ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Unilever R and D   (China)

Author keywords

Bile salts; Curcumin; Lipids; Micelle; Solubility

Indexed keywords

EID: 78649461052     PISSN: 10063080     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. 2005, 36(11): 1737-1740.
2. 2006(4): 14-15.
3. 2005, 26(6): 614-616.
4. 2007, 21(6): 73-76.
5. 2008, 29(1): 40-47.
6. Wiedmann T S, Kamel L. Examination of the solubilization of drugs by bile salt micelles[J]. Journal of Pharmaceutical Sciences, 2002, 91(8): 1743-1764.
7. Wiedmann T S, Liang W, Kamel L. Solubilization of drugs by physiological mixtures of bile salts [J]. Pharmaceutical Research, 2002, 19(8): 1203-1207.
8. Porter C J H, Trevaskis N L, Charman W N. Lipid and lipid based formulations: Optimizing the oral delivery of lipophilic drugs[J]. Nature Reviews, 2007, 6: 231-248.
9. Cai X H, Grant D J W, Wiedmann T S. Analysis of the solu-bilization of steroids by bile salt micelles[J]. Journal of Pharmaceutical Sciences, 1997, 86(3): 372-377.
10. Groel A, Kunnumakkara A B, Aggarwal B B. Curcumin as "curecumin": From kitchen to clinic[J]. Biochemical Pharmacology, 2008, 25: 787-809.
11. Staggers J E, Hernell, O, Stafford R J, et al. Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption: 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings [J]. Biochemistry, 1990, 29: 2028-2040.
12. Wang D Q H, Carey M C. Characterization of crystallization pathways during cholesterol precipitation from human gallbladder biles: Identical pathways to corresponding model biles with three predominating sequences[J]. J Lipid Res, 1996, 37: 606-630.
13. MePnikov S M, Seijen Ten Hoorn J W M, Eijkelenboom A P A M. Effect of phtosterols and phtostanols on the solubilization of cholesterol by dietary mixed micelles: An in vitro study[J]. Chemistry and Physics of Lipids, 2004, 127: 121-141.
14. 1991, 11(2): 18-20.
15. 2007, 29(2): 291-293.
16. Li C Y, Zimmerman C L, Wiedmann T S. Solubilization of retinoids by bile salt/phospholipid aggregates [J]. Pharmaceutical Research, 1996, 13(6): 907-913.
17. Luner P E, Babu S R, Radebaugh G W. The effects of bile salts and lipids on the physicochemical behavior of gemfibrozil [J]. Pharmaceutical Research, 1994, 11(12): 1755-1760.
18. Schwarz M A, Raith K, Dongowski G, et al. Effect on the partition equilibrium of various drugs by formation of mixed bile salt/phosphatidylcholine/fatty acid micelles a characterization by micellar afftinity capillary electrophoresis: Part IV. [J]. Journal of Chromatography A, 1998, 809: 219-229.
19. Tangerman A, Shaik A V, Hoek E W. Analysis of conjugated and unconjugated bile acids in serum and jejunal fluid of normal subjects[J]. Clin Chem Acta, 1986, 159:123-132.
20. RangelYagui C O, Pessoa-jr A, Tavares L C. Micellar solubilization of drugs[J]. J Pharm Pharmaceut Sci, 2005, 8(2): 147-163.
21. Florence A T, Attwood D. Physicochemical Principles of Pharmacy [M]. 3rd ed. London: The MacMilllan Press, 2003.
22. Takahashi Y I, Underwood B A. Effect of long and medium chain length lipids upon aqueous solubility of crtocopherol [J]. Lipids, 1974, 9(11): 855-859.
23. Bonsdorff-Nikander A V, Christiansen L, Huikko L, et al. A comparison of the effect of medium- vs. long-chain triglycerides on the in vitro solubilization of cholesterol and/or phytosterol into mixed micelles [J]. Lipids, 2005, 40(2): 181-190.