Novel free radical monitoring in patients with neurological emergency diseases

Acta Neurochirurgica, Supplementum

Volumn , Issue 106, 2009, Pages 315-319

  Dohi, Kenji ^a   Satoh, Kazue ^b   Nakamachi, Tomoya ^a   Ohtaki, Hirokazu ^a   Yofu, Sachiko ^a   Nakamura, Shunsuke ^b   Shioda, Seiji ^b   Aruga, Tohru ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

alkoxyl radical; brain hypothermia; d ROM test; free radical; Head injury; human; monitoring; oxidative stress

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; NORPHENAZONE; REACTIVE OXYGEN METABOLITE;

ADULT; AGED; BLOOD SAMPLING; BRAIN INFARCTION; CASE REPORT; CONFERENCE PAPER; ELECTRON SPIN RESONANCE; EX VIVO STUDY; FEMALE; HUMAN; INTERNAL JUGULAR VEIN; MALE; NERVOUS SYSTEM INJURY; NEUROLOGIC DISEASE; NON INVASIVE PROCEDURE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PATIENT MONITORING; SPECTROMETER; SPIN TRAPPING; SUBDURAL HEMATOMA; VEIN CATHETERIZATION;

EID: 78649453535     PISSN: 00651419     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-211-98811-4_59     Document Type: Conference Paper

References (21)

1. Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P (1997) Oxidative DNA damage in the Parkinsonian brain: An apparent selective increase in 8-hydroxy-guanine levels in substantia nigra. J Neurochem 69:1196-1203
2. Cernak I, O'Connor C, Vink R (2002) Inhibition of cyclooxygenase 2 by nimesulide improves cognitive outcome more than motor outcome following diffuse traumatic brain injury in rats. Exp Brain Res 147(2):193-199
3. Chan PH (1996) Role of oxidants in ischemic brain damage. Stroke 27:1124-1129
4. Dohi K, Ohtaki H, Inn R, Ikeda Y, Shioda HS, Aruga T (2003) Peroxynitrite and caspase-3 expression after ischemia/reperfusion in mouse cardiac arrest model. Acta Neurochir Suppl 86:87-91
5. Dohi K, Satoh K, Nakamachi T, Yofu S, Hiratsuka K, Nakamura S, Ohtaki H, Yoshikawa T, Shioda S, Aruga T (2007) Does edaravone (MCI-186) act as an antioxidant and a neuroprotector in experimental traumatic brain injury? Antioxid Redox Signal 9(2): 281-287
6. Dohi K, Satoh K, Ikeda Y, Ohtaki H, Shioda S, Aruga T (2003) Neuroprotective effect from ischemia and direct free radical scavenging activity of Choto-san (kampo medicine). Acta Neurochir Suppl 86:123-127
7. Dohi K, Satoh K, Mihara Y, Nakamura S, Miyake Y, Ohtaki H, Nakamachi T, Yoshikawa T, Shioda S, Aruga T (2006) Alkoxyl radical-scavenging activity of edaravone in patients with traumatic brain injury. J Neurotrauma 23(11):1591-1599
8. Dohi K, Satoh K, Moriwaki H, Mihara Y, Miyake Y, Ohtaki H, Shioda S, Aruga T (2005) Levels of the alkoxy radical in patients with brain death. In: Shioda S, Hommma T (eds) Breathing, feeding, and neuroprotection. Springer, Tokyo
9. Dohi K, Satoh K, Ohtaki H, Shioda S, Miyake Y, Shindo M, Aruga T (2005) Elevated plasma levels of bilirubin in patients with neurotrauma reflect its pathophysiological role in free radical scavenging. In Vivo 19(5):855-860
10. Houkin K, Nakayama N, Kashiwada T (2003) Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters. Cerebrovasc Dis 15(3):222-229
11. Jimbo H, Dohi K, Nakamura Y, Izumiyama H, Ikeda Y, Matsumoto K, Kushima M, Takaki A (2000) Fatal severe vasospasm due to rewarming following hypothermia - case report. Neurol Med Chir 40(9):463-466
12. Kasai H, Nishimura S (1984) Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 12:2137-2145
13. Lewen A, Matz P, Chan PH (2000) Free radical pathways in CNS injury. J Neurotrauma 17:871-890
14. Mihara Y, Dohi K, Satoh K, Moriwaki H, Kuroki T, Miyake Y, Shioda S, Aruga T (2004) Mild brain hypothermia suppresses oxygen free radical in patients with neuroemergency: An ex vivo electron spin resonance study. In: Hayashi N, Bullock R, Dietrich DW, Maekawa T, Tamura A (eds) Hypothermia for acute brain damage. Springer, Tokyo
15. Ohtaki H, Funahashi H, Dohi K, Oguro T, Horai R, Asano M, Iwakura Y, Yin L, Matsunaga M, Goto N, Shioda S (2003) Suppression of oxidative neuronal damage after transient middle cerebral artery occlusion in mice lacking interleukin-1. Neurosci Res 45(3):313-324
16. Ohtaki H, Takeda T, Dohi K, Yofu S, Nakamachi T, Satoh K, Hiraizumi Y, Miyaoka H, Matsunaga M, Shioda S (2007) Increased mitochondrial DNA oxidative damage after transient middle cerebral artery occlusion in mice. Neurosci Res 58(4):349-355
17. Satoh K, Ikeda Y, Shioda S, Tobe T, Yoshikawa T (2002) Edaravone scavenges nitric oxide. Redox Rep 7(4):219-222
18. Smith MA, Rottkamp CA, Nunomura A, Raina AK, Perry G (2000) Oxidative stress in Alzheimer's disease. Biochim Biophys Acta 1502(1):139-144
19. Toyokuni S, Tanaka T, Hattori Y, Nishiyama Y, Yoshida A, Uchida K, Hiai H, Ochi H, Osawa T (1997) Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate- induced renal carcinogenesis model. Lab Invest 76(3): 365-374.
20. Watanabe T, Yuki S, Egawa M, Nishi H (1994) Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions. J Pharmacol Exp Ther 268(3):1597-1604
21. Yamanaka G, Kawashima H, Suganami Y, Watanabe C, Watanabe Y, Miyajima T, Takekuma K, Oguchi S, Hoshika A (2006) Diagnostic and predictive value of CSF d-ROM level in influenza virus-associated encephalopathy. J Neurol Sci 15; 243(1-2):71-75