A not so simple analgesic

NDT Plus

Volumn 3, Issue 6, 2010, Pages 573-575

  Howie, Sarah ^a   Tarn, Anne ^a   Soper, Charles ^a  

^a MAYDAY UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

acidosis; anion gap; oxoproline; paracetamol; pyroglutamate

Indexed keywords

AMOXICILLIN; COCODAMOL; ERYTHROMYCIN; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PYROGLUTAMIC ACID; VITAMIN B GROUP;

ADULT; ARTHRALGIA; ARTICLE; CASE REPORT; CESAREAN SECTION; CHEST INFECTION; DYSPNEA; FEMALE; HEMODIAFILTRATION; HUMAN; KIDNEY FUNCTION; LONG TERM CARE; METABOLIC ACIDOSIS; PREGNANT WOMAN; PRIORITY JOURNAL; PYOGLUTAMIC ACIDOSIS; PYROGLUTAMIC ACIDOSIS; URINARY TRACT INFECTION; UTERUS CONTRACTION;

EID: 78649452185     PISSN: 17530784     EISSN: 17530792     Source Type: Journal    
DOI: 10.1093/ndtplus/sfq153     Document Type: Article

References (10)

1. Fenves AZ, Kirkpatrick HM III, Viralkumar VP et al. Increased anion gap metabolic acidosis as a result of 5-oxoproline (pyroglutamic acid): a role for acetaminophen. Clin J Am Soc Nephrol 2006; 1: 441-447
2. Pitt JJ, Hauser S. Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects. Clin Chem 1998; 44: 1497-1503
3. Ookhtens M, Kaplowitz N. Role of the liver in interorgan homeostasis of glutathione and cyst(e)ine. Semin Liver Dis 1998; 18: 313-329 (Pubitemid 29011037)
4. Persaud C, Forrester T, Jackson AA. Urinary excretion of 5-L-oxopro-line (pyroglutamic acid) is increased during recovery from severe childhood malnutrition and responds to supplemental glycine. J Nutr 1996; 126: 2823-2830
5. Jackson AA, Badaloo AV, Forrester T et al. Urinary excretion of 5-oxoproline (pyroglutamic acid) as an index of glycine insufficiency in normal man. Br J Nutr 1987; 58: 207-214
6. Jackson AA, Persaud C, Werkmeister G et al. Comparison of urinary 5-L-oxoproline (L-pyroglutamate) during normal pregnancy in women in England and Jamaica. Br J Nutr 1997; 77: 183-196
7. Persaud C, McDermott J, De Benoist B et al. The excretion of 5-oxoproline in urine, as an index of glycine status, during normal pregnancy. Br J Obstet Gynaecol 1989; 96: 440-444
8. Humphreys BD, Forman JP, Zandi-Nejad K et al. Acetaminophen-induced anion gap metabolic acidosis and 5-oxoprolinuria (pyroglu-tamic aciduria) acquired in hospital. Am J Kidney Dis 2005; 46: 143-146
9. Kortman W, van Agtmael MA, van Diessen J et al. 5-Oxoproline as a cause of high anion gap metabolic acidosis: an uncommon cause with common risk factors. Neth J Med 2008; 66: 354-357
10. Croal BL, Glen AC, Kelly CJ et al. Transient 5-oxoprolinuria (pyroglutamic aciduria) with systemic acidosis in an adult patient receiving antibiotic therapy. Clin Chem 1998; 44: 336-340