Angiotensin II-induced smooth muscle cell migration is mediated by LDL receptor-related protein 1 via regulation of matrix metalloproteinase 2 expression

Biochemical and Biophysical Research Communications

Volumn 402, Issue 4, 2010, Pages 577-582

  Jung, Hae Ok ^a   Uhm, Jae Sun ^a   Seo, Suk Min ^a   Kim, Jee Hee ^a   Youn, Ho Joong ^a   Baek, Sang Hong ^a   Chung, Wook Sung ^a   Seung, Ki Bae ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Angiotensin II; LRP1; Matrix metalloproteinase 2; Migration; Smooth muscle cells

Indexed keywords

ANGIOTENSIN II; GELATINASE A; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME REGULATION; LIGAND BINDING; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ANGIOTENSIN II; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; GENE KNOCKDOWN TECHNIQUES; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MATRIX METALLOPROTEINASE 2; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING;

RATTUS;

EID: 78649446632     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.10.019     Document Type: Article

References (26)

1. Schwartz S.M., Heimark R.L., Majesky M.W. Developmental mechanisms underlying pathology of arteries. Physiol. Rev. 1990, 70:1177-1209.
2. Owens G.K. Regulation of differentiation of vascular smooth muscle cells. Physiol. Rev. 1995, 75:487-517.
3. Jiang M., Bujo H., Zhu Y., Yamazaki H., Hirayama S., Kanaki T., Shibasaki M., Takahashi K., Schneider W.J., Saito Y. Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells. Biochem. Biophys. Res. Commun. 2006, 348:1367-1377.
4. Jiang M., Bujo H., Ohwaki K., Unoki H., Yamazaki H., Kanaki T., Shibasaki M., Azuma K., Harigaya K., Schneider W.J., Saito Y. Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice. J. Clin. Invest. 2008, 118:2733-2746.
5. Zuo L., Ushio-Fukai M., Ikeda S., Hilenski L., Patrushev N., Alexander R.W. Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophy. Arterioscler. Thromb. Vasc. Biol. 2005, 25:1824-1830.
6. Horiuchi M., Cui T.X., Li Z., Li J.M., Nakagami H., Iwai M. Fluvastatin enhances the inhibitory effects of a selective angiotensin II type 1 receptor blocker, valsartan, on vascular neointimal formation. Circulation 2003, 107:106-112.
7. Desrosiers R.R., Rivard M.E., Grundy P.E., Annabi B. Decrease in LDL receptor-related protein expression and function correlates with advanced stages of Wilms tumors. Pediatr. Blood Cancer 2006, 46:40-49.
8. Chazaud B., Ricoux R., Christov C., Plonquet A., Gherardi R.K., Barlovatz-Meimon G. Promigratory effect of plasminogen activator inhibitor-1 on invasive breast cancer cell populations. Am. J. Pathol. 2002, 160:237-246.
9. Wijnberg M.J., Quax P.H., Nieuwenbroek N.M., Verheijen J.H. The migration of human smooth muscle cells in vitro is mediated by plasminogen activation and can be inhibited by alpha2-macroglobulin receptor associated protein. Thromb. Haemost. 1997, 78:880-886.
10. Li Y., Lu W., Bu G. Essential role of the low density lipoprotein receptor-related protein in vascular smooth muscle cell migration. FEBS Lett. 2003, 555:346-350.
11. Song H., Li Y., Lee J., Schwartz A.L., Bu G. Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. Cancer Res. 2009, 69:879-886.
12. Herz J., Strickland D.K. LRP: a multifunctional scavenger and signaling receptor. J. Clin. Invest. 2001, 108:779-784.
13. Llorente-Cortes V., Badimon L. LDL receptor-related protein and the vascular wall: implications for atherothrombosis. Arterioscler. Thromb. Vasc. Biol. 2005, 25:497-504.
14. Handschug K., Schulz S., Schnurer C., Kohler S., Wenzel K., Teichmann W., Glaser C. Low-density lipoprotein receptor-related protein in atherosclerosis development: up-regulation of gene expression in patients with coronary obstruction. J. Mol. Med. 1998, 76:596-600.
15. Llorente-Cortes V., Martinez-Gonzalez J., Badimon L. LDL receptor-related protein mediates uptake of aggregated LDL in human vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 2000, 20:1572-1579.
16. Sendra J., Llorente-Cortes V., Costales P., Huesca-Gomez C., Badimon L. Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension. Cardiovasc. Res. 2008, 78:581-589.
17. Newby A.C. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc. Res. 2006, 69:614-624.
18. Song H., Cha M.J., Song B.W., Kim I.K., Chang W., Lim S., Choi E.J., Ham O., Lee S.Y., Chung N., Jang Y., Hwang K.C. Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex. Stem Cells 2010, 28:555-563.
19. Bu G., Rennke S. Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein. J. Biol. Chem. 1996, 271:22218-22224.
20. Doran A.C., Meller N., McNamara C.A. Role of smooth muscle cells in the initiation and early progression of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2008, 28:812-819.
21. Chazaud B., Bonavaud S., Plonquet A., Pouchelet M., Gherardi R.K., Barlovatz-Meimon G. Involvement of the [uPAR:uPA:PAI-1:LRP] complex in human myogenic cell motility. Exp. Cell Res. 2000, 258:237-244.
22. Okada S.S., Grobmyer S.R., Barnathan E.S. Contrasting effects of plasminogen activators, urokinase receptor, and LDL receptor-related protein on smooth muscle cell migration and invasion. Arterioscler. Thromb. Vasc. Biol. 1996, 16:1269-1276.
23. Weaver A.M., Hussaini I.M., Mazar A., Henkin J., Gonias S.L. Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin. J. Biol. Chem. 1997, 272:14372-14379.
24. Webb D.J., Nguyen D.H., Gonias S.L. Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion. J. Cell Sci. 2000, 113(Pt. 1):123-134.
25. Sid B., Dedieu S., Delorme N., Sartelet H., Rath G.M., Bellon G., Martiny L. Human thyroid carcinoma cell invasion is controlled by the low density lipoprotein receptor-related protein-mediated clearance of urokinase plasminogen activator. Int. J. Biochem. Cell Biol. 2006, 38:1729-1740.
26. Foca C., Moses E.K., Quinn M.A., Rice G.E. Differential expression of the alpha(2)-macroglobulin receptor and the receptor associated protein in normal human endometrium and endometrial carcinoma. Mol. Hum. Reprod. 2000, 6:921-927.