Upper airway reflexes in response to gastric reflux

Paediatric Respiratory Reviews

Volumn 11, Issue 4, 2010, Pages 208-212

  Praud, Jean Paul ^a  

^a UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

Apnoea of prematurity; Apparent life threatening event; Laryngeal chemoreflexes; Laryngopharyngeal reflux; Sudden infant death syndrome

Indexed keywords

ACETAZOLAMIDE; ADENOSINE RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; DIPHENHYDRAMINE; LIDOCAINE;

ACIDOSIS; ANEMIA; APNEA; BREATHING REFLEX; CHEMORECEPTOR REFLEX; CIGARETTE SMOKING; GASTROINTESTINAL REFLUX; HUMAN; HYPERCAPNIA; HYPERTHERMIA; HYPOXIA; LARYNGEAL CHEMOREFLEX; LARYNGITIS; LARYNGOPHARYNGEAL REFLUX; NERVE CELL MEMBRANE POTENTIAL; NEWBORN APNEA; NONHUMAN; PATHOGENESIS; PERINATAL PERIOD; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT MUCOSA; REVIEW; SEDATION; SUDDEN INFANT DEATH SYNDROME; UPPER RESPIRATORY TRACT;

HUMANS; INFANT, NEWBORN; REFLEX; REGURGITATION, GASTRIC;

EID: 78649442489     PISSN: 15260542     EISSN: 15260550     Source Type: Journal    
DOI: 10.1016/j.prrv.2010.07.001     Document Type: Review

References (48)

1. McGeady Gastroesophageal reflux disease in children and adolescents. Gastroesophageal reflux disease and airway disease. Lung Biology in Health and Disease 1999, 129:237-268. Marcel Dekker, New York.
2. Johnson P., Dawes D.S., Robinson J.S. Maintenance of breathing in newborn lamb (Abstract). Arch Dis Child 1972, 47:151.
3. Negus V.E. The Comparative Anatomy and Physiology of the Larynx 1949, Heinemann, London.
4. Thach B.T. Some aspects of clinical relevance in the maturation of respiratory control in infants. J Appl Physiol 2008, 104:1828-1834.
5. St Hilaire M., Nsegbe E., Gagnon-Gervais K., et al. Laryngeal chemoreflexes induced by acid vs. water vs. saline in non-sedated newborn lambs during quiet sleep. J Appl Physiol 2005, 98:2197-2203.
6. Boggs D.F., Bartlett D. Chemical specificity of a laryngeal apneic reflex in puppies. J Appl Physiol 1982, 53:455-462.
7. Downing S.E., Lee J.C. Laryngeal chemosensitivity: a possible mechanism for sudden infant death. Pediatrics 1975, 55:640-649.
8. Heman-Ackah Y.D., Pernell K.J., Goding G.S. The laryngeal chemoreflex: an evaluation of the normoxic response. Laryngoscope 2009, 119:370-379.
9. St-Hilaire M., Samson N., Nsegbe E., et al. Postnatal maturation of laryngeal chemoreflexes in the preterm lamb. J Appl Physiol 2007, 102:1429-1438.
10. Kelly E.J., Newell S.J., Brownlee K.G., Primrose J.N., Dear P.R. Gastric acid secretion in preterm infants. Early Hum Dev 1993, 35:215-220.
11. Gomes H., Lallemand P. Infant apnea and gastroesophageal reflux. Pediatr Radiol 1992, 22:8-11.
12. Thach B.T. Reflux associated apnea in infants: evidence for a laryngeal chemoreflex. Am J Med 1997, 103:120S-124S.
13. Edner A., Wennborg M., Alm B., Lagercrantz H. Why do ALTE infants not die in SIDS?. Acta Paediatr 2007, 96:191-194.
14. Yamamoto Y., Atoji Y., Suzuki Y. Innervation of taste buds in the canine larynx as revealed by immunohistochemistry for the various neurochemical markers. Tissue Cell 1997, 29:339-346.
15. Widdicombe J. Airway receptors. Respir Physiol 2001, 125:3-15.
16. Valenzano K.J., Sun Q. Current perspectives on the therapeutic utility of VR1 antagonists. Curr Medicin Chem 2004, 11:3185-3202.
17. Fisher J.T. The TRPV1 ion channel: implications for respiratory sensation and dyspnea. Respir Physiol Neurobiol 2009, 167:45-52.
18. Marchal F., Corke B.C., Sundell H. Reflex apnea from laryngeal chemo-stimulation in the sleeping premature newborn lamb. Pediatr Res 1982, 16:621-627.
19. Vermeylen D., Franco P., Hennequin Y., Pardou A., Brugmans M., Simon P., Hassid S. Laryngeal oedema in neonatal apnoea and bradycardia syndrome (a pilot study). Early Hum Dev 2005, 81:361-367.
20. McKelvey G.M., Post E.J., Wood A.K.W., Jeffery H.E. Airway protection following simulated gastro-oesophageal reflux in sedated and sleeping neonatal piglets during active sleep. Clin Exp Pharmacol Physiol 2001, 28:533-539.
21. Curran A.K., Xia L., Leiter J.C., Bartlett D. Elevated body temperature enhances the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol 2005, 98:780-786.
22. Xia L., Damon T.A., Leiter J.C., Bartlett D. Focal warming of the nucleus of the solitary tract prolongs the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol 2006, 102:54-62.
23. Xia L., Damon T., Niblock M.M., Bartlett D., Leiter J.C. Unilateral microdialysis of gabazine in the dorsal medulla reverses thermal prolongation of the laryngeal chemoreflex in decerebrate piglets. J Appl Physiol 2007, 103:1864-1872.
24. Sundell H.W., Karmo H., Milerad J. Impaired cardiorespiratory recovery after laryngeal stimulation in nicotine-exposed young lambs. Pediatr Res 2003, 53:104-112.
25. Xia L., Leiter J.C., Bartlett D. Gestational nicotine exposure exaggerates hyperthermic enhancement of laryngeal chemoreflex in rat pups. Respir Physiol Neurobiol 2010, 171(1):17-21.
26. Lindgren C., Grogaard J. Reflex apnoea response and inflammatory mediators in infants with respiratory tract infection. Acta Paediatr 1996, 85:798-803.
27. Lindgren C., Lin J., Graham B.S., Gray M.E., Parker R.A., Sundell H.W. Respiratory syncytial virus infection enhances the response to laryngeal chemostimulation and inhibits arousal from sleep in young lambs. Acta Paediatr 1996, 85:789-797.
28. Ralston S., Hill V. Incidence of apnea in infants hospitalized with respiratory syncytial virus bronchiolitis: a systematic review. J Pediatr 2009, 155:728-733.
29. Fagenholz S.A., Lee J.C., Downing S.E. Association of anemia with reduced central respiratory drive in the piglet. Yale J Biol Med 1979, 52:263-270.
30. Wennergren G., Hertzberg T., Milerad J., Bjure J., Lagercrantz H. Hypoxia reinforces laryngeal reflex bradycardia in infants. Acta Paediatr Scand 1989, 78:11-17.
31. Pickens D.L., Schefft G.L., Thach B.T. Pharyngeal fluid clearance and aspiration preventive mechanisms in sleeping infants. J Appl Physiol 1989, 66:1164-1171.
32. Page M., Jeffery H.E., Marks V., Post E.J., Wood A.K.W. Mechanisms of airway protection after pharyngeal infusion in healthy, sleeping piglets. J Appl Physiol 1995, 78:1942-1949.
33. Page M., Jeffery H.E. Airway protection in sleeping infants in response to pharyngeal fluid stimulation in the supine position. Pediatr Res 1998, 44:691-698.
34. Heman-Ackah Y.D., Goding G.S. Effects of intralaryngeal carbon dioxide and acetazolamide on the laryngeal chemoreflex. Ann Otol Rhinol Laryngol 2000, 109:921-928.
35. Grogaard J., Kreuger E., Lindstrom D., Sundell H. Effects of carotid body maturation and terbutaline on the laryngeal chemoreflex in newborn lambs. Pediatr Res 1986, 20:724-729.
36. Bauman N.M., Wang D., Jaffe D.A., Sandler A.D., Luschei E.D. Effect of intravenous calcitonin gene-related peptide antagonist on the laryngeal chemoreflex in piglets. Otolaryngol Head Neck Surg 1999, 121:1-6.
37. Downs D.H., Johnson K., Goding G.S. The effect of antihistamines on the laryngeal chemoreflex. Laryngoscope 1995, 105:857-861.
38. McCulloch T.M., Flint P.W., Richardson M.A., Bishop M.J. Lidocaine effects on the laryngeal chemoreflex, mechanoreflex, and afferent electrical stimulation reflex. Ann Otol Rhinol Laryngol 1992, 101:583-589.
39. Slocum C., Hibbs A.M., Martin R.J., Orenstein S.R. Infant apnea and gastroesophageal reflux: a critical review and framework for further investigation. Curr Gastroenterol Rep 2007, 9:219-224.
40. Kimball A.L., Carlton D.P. Gastroesophageal reflux medications in the treatment of apnea in premature infants. J Pediatr 2001, 138:355-360.
41. Ramet J., Praud J.-P., d'Allest A.M., Dehan M., Guilleminault C., Gaultier C. Cardiac and respiratory responses to esophageal dilatation during REM sleep in human infants. Biol Neonate 1990, 58:181-187.
42. McGovern M.C., Smith M.B. Causes of apparent life threatening events in infants: a systematic review. Arch.Dis.Child. 2004, 89:1043-1048.
43. Leiter J.C., Böhm I. Mechanisms of pathogenesis in Sudden Infant Death Syndrome. Respir Physiol Neurobiol 2007, 159:127-138.
44. Thurnheer R., Henz S., Knoblauch A. Sleep-related laryngospasm. Eur Respir J 1997, 10:2084-2086.
45. Roland M.M., Baran A.S., Richert A.C. Sleep-related laryngospasm caused by gastroesophageal reflux. Sleep Med 2008, 9:451-453.
46. Karkos P.D., Leong S.C., Benton J., Sastry A., Assimakopoulos D.A., Issing W.J. Reflux and sleeping disorders: a systematic review. J Laryngol Otol 2009, 123:372-374.
47. Orenstein S.R., Kocoshis S.A., Orenstein D.M., Proujansky R. Stridor and gastroesophageal reflux: diagnostic use of intraluminal esophageal acid perfusion (Bernstein test). Pediatr Pulmonol 1987, 3:420-424.
48. Reix P., St-Hilaire M., Praud J.-P. Laryngeal sensitivity in the neonatal period: from bench to bedside. Pediatr Pulmonol 2007, 42:674-682.