Effect of experimental diabetes and STZ on male fertility capacity. Study in rats

Journal of Andrology

Volumn 31, Issue 6, 2010, Pages 584-592

  Navarro Casado, Laura ^a   Juncos Tobarra, M A ^a   Chafer Rudilla M ^a   Iniguez De Onzono L ^a   Blazquez Cabrera J A ^a   Miralles Garcia J M ^b  

^a HOSPITAL GENERAL UNIVERSITARIO DE ALBACETE   (Spain)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

Fertility; Semen; Semen analysis; Sperm; Testis

Indexed keywords

TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EPIDIDYMIS; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MALE FERTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEMEN ANALYSIS; SPERMATOZOON ABNORMALITY; STREPTOZOCIN DIABETES; TERATOZOOSPERMIA; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; EPIDIDYMIS; INFERTILITY, MALE; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; SEMEN ANALYSIS; TESTIS; TESTOSTERONE;

EID: 78649433345     PISSN: 01963635     EISSN: 19394640     Source Type: Journal    
DOI: 10.2164/jandrol.108.007260     Document Type: Article

References (28)

1. Agarwal A, Said TM. Carnitines and male infertility. Reprod Biomed Online. 2004;8:376-384.
2. Agbaje IM, McVicar CM, Schock BC, McClure N, Atkinson AB, Rogers D, Lewis SE. Increased concentrations of the oxidative DNA adduct 7,8-dihydro-8-oxo-2- deoxyguanosine in the germ-line of men with type 1 diabetes. Reprod Biomed Online. 2008;16(3):401-409. (Pubitemid 351419460)
3. Ali ST, Shaikh RN, Siddiqi NA, Siddiqi PQ. Semen analysis in insulin-dependent/non-insulin-dependent diabetic men with/without neuropathy. Arch Androl. 1993;30:47-54. (Pubitemid 23041286)
4. Amaral S, Moreno AJ, Santos MS, Seica R, Ramalho-Santos J. Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes. Theriogenology. 2006;66(9):2056-2067. (Pubitemid 46048513)
5. Anderson JE, Jones D, Penner SB, Thliveris JA. Primary hypoandrogenism in experimental diabetes in the Long-Evans rats. Diabetes. 1987;36:1104-1110. (Pubitemid 17163414)
6. Anderson JE, Thliveris JA. Testicular histology in streptozotocin-induced diabetes. Anat Rec. 1986;214(4):378-382.
7. Anderson JE, Thliveris JA. Morphometry and cytochemistry of Leydig cells in experimental diabetes. Am J Anat. 1987;180:41-48. (Pubitemid 17140287)
8. Andersson B, Marin P, Lissner L, Vermeulen A, Bjorntorp P. Testosterone concentrations in women and men with NIDDM. Diabetes Care. 1994;17:405-411.
9. Ballester J, Munoz MC, Dominguez J, Rigau T, Guinovart JJ, Rodriguez-Gil JE. Insulin-dependent diabetes affects testicular function by FSH- and LH-linked mechanisms. J Androl. 2004;25:706-719. (Pubitemid 39096304)
10. Bartak V. Sperm quality in adult diabetic men. Int J Fertil. 1979;24:226-232. (Pubitemid 10149511)
11. Bolzan AD, Bianchi MS. Genotoxicity of streptozotocin. Mutat Res. 2002;512:121-134.
12. Cai L, Chen S, Evans T, Deng DX, Mukherjee K, Chakrabarti S. Apoptotic germ-cell death and testicular damage in experimental diabetes: prevention by endothelin antagonism. Urol Res. 2000;28:342-347.
13. Cameron DF, Murray FT, Drylie DD. Interstitial compartment pathology and spermatogenic disruption in testes from impotent diabetic men. Anat Rec. 1985;213:53-62.
14. Cooke PS, Hess RA, Porcelli J, Meisami E. Increased sperm production in adult rats after transient neonatal hypothyroidism. Endocrinology. 1991;129:244-248.
15. Escrig A, Marin R, Abreu P, Gonzalez-Mora JL, Mas M. Changes in mating behavior, erectile function, and nitric oxide levels in penile corpora cavernosa in streptozotocin-diabetic rats. Biol Reprod. 2002;66:185-189. (Pubitemid 34020602)
16. Ford WC, Hamilton DW. The effect of experimentally induced diabetes on the metabolism of glucose by seminiferous tubules and epididymal spermatozoa from the rat. Endocrinology. 1984;115:716-722.
17. Jackson FL, Hutson JC. Altered responses to androgen in diabetic male rats. Diabetes. 1984;33:819-824.
18. Mallidis C, Agbaje IM, Rogers DA, Glenn JV, Pringle R, Atkinson AB, Steger K, Stitt AW, McClure N. Advanced glycation end products accumulate in the reproductive tract of men with diabetes. Int J Androl. 2009;32(4):295-305.
19. Murray FT, Cameron DF, Vogel RB, Thomas RG, Wyss HU, Zauner CW. The pituitary-testicular axis at rest and during moderate exercise in males with diabetes mellitus and normal sexual function. J Androl. 1988;9:197-206.
20. Oksanen A. Testicular lesions of streptozotocin diabetic rats. Horm Res. 1975;6:138-144.
21. Orth JM, Murray FT, Bardin CW. Ultrastructural changes in Leydig cells of streptozotocin-induced diabetic rats. Anat Rec. 1979;195:415-430. (Pubitemid 10210896)
22. Padron RS, Dambay A, Suarez R, Mas J. Semen analyses in adolescent diabetic patients. Acta Diabetol Lat. 1984;21:115-121.
23. Paz G, Homonnai ZT. Leydig cell function in streptozotocin-induced diabetic rats. Experientia. 1979;35:1412-1413. (Pubitemid 10236099)
24. Pitteloud N, Hardin M, Dwyer AA, Valassi E, Yialamas M, Elahi D, Hayes FJ. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005;90:2636-2641. (Pubitemid 40686302)
25. Rodriguez-Rigau LJ. Diabetes and male reproductive function. J Androl. 1980;1:105-110.
26. Soudamani S, Malini T, Balasubramanian K. Effects of streptozotocin- diabetes and insulin replacement on the epididymis of prepubertal rats: histological and histomorphometric studies. Endocr Res. 2005;31:81-98. (Pubitemid 41759224)
27. Vignon F, Le Faou A, Montagnon D, Pradignac A, Cranz C, Winiszewsky P, Pinget M. Comparative study of semen in diabetic and healthy men. Diabete Metab. 1991;17:350-354.
28. Wade MA, Jones RC, Murdoch RN, Aitken RJ. Motility activation and second messenger signalling in spermatozoa from rat cauda epididymidis. Reproduction. 2003;125:175-183.