In vitro effects of Echis carinatus venom on the human plasma proteome

Proteomics

Volumn 10, Issue 20, 2010, Pages 3712-3722

  Guerranti, Roberto ^a,b   Cortelazzo, Alessio ^a   Hope Onyekwere, Nnadozie S ^a   Furlani, Emiliano ^a   Cerutti, Helena ^a   Puglia, Michele ^a   Bini, Luca ^a   Leoncini, Roberto ^a,b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL OF SIENA   (Italy)

Author keywords

2 D PAGE; Animal proteomics; Plasma proteome; Proteases; Protein fragmentation; Snake venom

Indexed keywords

ALPHA 1 ANTITRYPSIN; APOLIPOPROTEIN A1; COMPLEMENT COMPONENT C4A; ECARIN; ECHIS VENOM; FIBRINOGEN; HAPTOGLOBIN; HEMOGLOBIN; HEMOPEXIN; PREALBUMIN; PROTEINASE; PROTEINASE INHIBITOR; PROTEOME; PROTHROMBIN; RETINOL BINDING PROTEIN 4; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BLOOD; BLOOD CLOTTING; ENVENOMATION; HUMAN; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN METABOLISM;

ANIMALS; BLOOD PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEOME; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; VIPER VENOMS; VIPERIDAE;

ANIMALIA; ECHIS CARINATUS;

EID: 78649413567     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000055     Document Type: Article

References (38)

1. Calvete, J. J., Sanz, L., Angulo, Y., Lomonte, B., Gutiérrez, J. M., Venoms, venomics, antivenomics. FEBS Lett. 2009, 583, 1736-1743.
2. Georgieva, D., Arni, R. K., Betzel, C., Proteome analysis of snake venom toxins: pharmacological insights. Expert Rev. Proteomics 2008, 5, 787-797.
3. Matsui, T., Fujimura, Y., Titani, K., Snake venom proteases affecting hemostasis and thrombosis. Biochim. Biophys. Acta 2000, 1477, 146-156.
4. Koh, D. C., Arumugam, A., Jeyaseelan, K., Snake venom components and their application in biomedicine. Cell. Mol. Life Sci. 2006, 63, 3030-3041.
5. Larréché, S., Mion, G., Goyffon, M., Haemostasis disorder caused by snake venoms. Ann. Fr. Anesth. Reanim. 2008, 27, 302-309.
6. Nishida, S., Fujita, T., Kohno, N., Atoda, H. et al., cDNA cloning and deduced amino acid sequence of prothrombin activator (ecarin) from Kenyan Echis carinatus venom. Biochemistry 1995, 34, 1771-1778.
7. Yamada, D., Sekiya, F., Morita, T., Isolation and characterization of carinactivase, a novel prothrombin activator in Echis carinatus venom with a unique catalytic mechanism. J. Biol. Chem. 1996, 271, 5200-5207.
8. Castro, H. C., Zingali, R. B., Albuquerque, M. G., Pujol-Luz, M., Rodrigues, C. R., Snake venom thrombin-like enzymes: from reptilase to now. Cell. Mol. Life Sci. 2004, 61, 843-856.
9. Tanos, P. P., Isbister, G. K., Lalloo, D. G., Kirkpatrick, C. M. J., Duffull, S. B., A model for venom-induced consumptive coagulopathy in snake bite. Toxicon 2008, 52, 769-780.
10. Ng, N. M., Pike, R. N., Boyd, S. E., Subsite cooperativity in protease specificity. Biol. Chem. 2009, 390, 401-407.
11. Anderson, N. L., Anderson, N. G., The human plasma proteome: history, character and diagnostic prospects. Mol. Cell. Proteomics 2002, 1, 845-867.
12. Liotta, L. A., Ferrari, M., Petricoin, E., Clinical proteomics: written in blood. Nature 2003, 425, 905.
13. Laemmli, U. K., Cleavage of structural proteins during the assembly of bacteriophage T4. Nature 1970, 227, 680-685.
14. Görg, A., Obermaier, C., Boguth, G., Harder, A. et al., The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 2000, 21, 1037-1053.
15. Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
16. Mortz, E., Krogh, T. N., Vorum, H., Görg, A., Improved silver staining protocols for high sensitivity protein identification using matrix-assisted laser desorption/ionization-time of flight analysis. Proteomics 2001, 1, 1359-1363.
17. Hellman, U., Wernstedt, C., Góñez, J., Heldin, C. H., Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal. Biochem. 1995, 224, 451-455.
18. Yi, J., Kim, C., Gelfand, C. A., Inhibition of intrinsic proteolytic activities moderates preanalytical variability and instability of human plasma. J. Proteome Res. 2007, 6, 1768-1781.
19. Overall, C. M., Blobel, C. P., In search of partners: linking extracellular proteases to substrates. Nat. Rev. Mol. Cell Biol. 2007, 8, 245-257.
20. Wu, W. B., Chang, S. C., Liau, M. Y., Huang, T. F., Purification, molecular cloning and mechanism of action of graminelysin I, a snake-venom-derived metalloproteinase that induces apoptosis of human endothelial cells. Biochem. J. 2001, 357, 719-728.
21. Rojnuckarin, P., Muanpasitporn, C., Chanhome, L., Arpijuntarangkoon, J., Intragumtornchai, T., Molecular cloning of novel serine proteases and phospholipases A2 from green pit viper (Trimeresurus albolabris) venom gland cDNA library. Toxicon 2006, 47, 279-287.
22. Siigur, J., Aaspõllu, A., Tõnism. agi, K., Trummal, K. et al., Proteases from Vipera lebetina venom affecting coagulation and fibrinolysis. Haemostasis 2001, 31, 123-132.
23. Matsui, T., Fujimura, Y., Titani, K., Snake venom proteases affecting hemostasis and thrombosis. Biochim. Biophys. Acta 2000, 1477, 146-156.
24. Kress, L. F., Kurecki, T., Chan, S. K., Laskowski, M., Sr., Characterization of the inactive fragment resulting from limited proteolysis of human alpha1-proteinase inhibitor by Crotalus adamanteus proteinase II. J. Biol. Chem. 1979, 254, 5317-5320.
25. Gans, H., Tan, B. H., Alpha-1-antitrypsin, an inhibitor for thrombin and plasmin. Clin. Chim. Acta 1967, 17, 111-117.
26. Niemann, M. A., Baggott, J. E., Miller, E. J., Inhibition of human serine proteases by SPAAT, the C-terminal 44-residue peptide from alpha1-antitrypsin. Biochim. Biophys. Acta 1997, 1340, 123-130.
27. Hassan, S., Sainz, I. M., Khan, M. M., Bradford, H. N. et al., Antithrombotic activity of kininogen is mediated by inhibitory effects of domain 3 during arterial injury in vivo. Am. J. Physiol. Heart Circ. Physiol. 2007, 292, 2959-2965.
28. Felicori, L. F., Souza, C. T., Velarde, D. T., Magalhaes, A. et al., Kallikrein-like proteinase from bushmaster snake venom. Protein Expr. Purif. 2003, 30, 32-42.
29. Taguchi, T., Kishikawa, H., Motoshima, H., Sakai, K. et al., Involvement of bradykinin in acute exercise-induced increase of glucose uptake and GLUT-4 translocation in skeletal muscle: studies in normal and diabetic humans and rats. Metabolism 2000, 49, 920-930.
30. Arnaud, P., Kalabay, L., Alpha2-HS glycoprotein: a protein in search of a function. Diabetes Metab. Res. Rev. 2002, 18, 311-314.
31. De Boer, J. P., Creasey, A. A., Chang, A., Abbink, J. J. et al., Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: studies using a baboon model. Infect. Immun. 1993, 61, 5035-5043.
32. Gasmi, A., Louzir, H., Karoui, H., el Ayeb, M., Dellagi, K., Purification from Vipera lebetina (desert adder) venom of a protein that depletes human complement. Nat. Toxins 1994, 2, 44-48.
33. Lee, M., Kovanen, P. T., Tedeschi, G., Oungre, E. et al., Apolipoprotein composition and particle size affect HDL degradation by chymase: effect on cellular cholesterol efflux. J. Lipid Res. 2003, 44, 539-546.
34. Raymond, W. W., Ruggles, S. W., Craik, C. S., Caughey, G. H., Albumin is substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site. J. Biol. Chem. 2003, 278, 34517-34524.
35. Zhang, A. S., Enns, C. A., Molecular mechanisms of normal iron homeostasis. Hematol. Am. Soc. Hematol. Educ. Program 2009, 207-214.
36. Polticelli, F., Bocedi, A., Minervini, G., Ascenzi, P., Human haptoglobin structure and function-a molecular modelling study. FEBS J. 2008, 275, 5648-5656.
37. Handelman, G. J., Levin, N. W., Iron and anemia in human biology: a review of mechanisms. Heart Fail. Rev. 2008, 13, 393-404.
38. Monaco, H. L., The transthyretin-retinol-binding protein complex. Biochim. Biophys Acta 2000, 1482, 65-72.