Antithrombotic activity of kininogen is mediated by inhibitory effects of domain 3 during arterial injury in vivo

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 6, 2007, Pages

  Hassan, Sarmina ^a   Sainz, Irma M ^a   Khan, Mohammad M ^a   Bradford, Harlan N ^a   Isordia Salas, Irma ^a   Kashem, Sakeen W ^a   Sartor, R Balfour ^b   Colman, Robert W ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Arterial thrombosis; Endothelial injury; Kininogen deficient rat

Indexed keywords

FIBRIN; GLUTATHIONE TRANSFERASE; HIGH MOLECULAR WEIGHT KININOGEN; KININOGEN; LOW MOLECULAR WEIGHT KININOGEN; THROMBIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICOAGULATION; AORTA INJURY; ARTERY INJURY; ARTICLE; BLOOD FLOW; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EXON; HYPOTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; RAT; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOSIS;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTITHROMBIN III; AORTA; BLOOD FLOW VELOCITY; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; FIBRIN; FIBRINOLYTIC AGENTS; GLUTATHIONE TRANSFERASE; KININOGEN, HIGH-MOLECULAR-WEIGHT; MALE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PLATELET AGGREGATION; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, INBRED LEW; RECOMBINANT FUSION PROTEINS; REGIONAL BLOOD FLOW; THROMBIN; THROMBOSIS;

EID: 34447503617     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00730.2006     Document Type: Article

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