Pharmacokinetic analysis of pralidoxime after its intramuscular injection alone or in combination with atropine-avizafone in healthy volunteers

British Journal of Pharmacology

Volumn 161, Issue 8, 2010, Pages 1857-1867

  Abbara, C ^a,b   Rousseau, J M ^c   Lelievre B ^a,b   Turcant, A ^a,b   Lallement, G ^d   Ferec, S ^a,b   Bardot, I ^e   Diquet, B ^a,b  

^a UNIVERSITÉ D'ANGERS   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c SERVICE D ENDOCRINOLOGIE   (France)

^d CENTRE DE RECHERCHES   (France)

^e Pharmacie centrale des Armées ^*  (France)

Author keywords

Bioavailability; Neurotoxic agents; Pharmacokinetics; Pralidoxime

Indexed keywords

ATROPINE; AVIZAFONE; DIAZEPAM; PRALIDOXIME; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADOLESCENT; ADULT; ATROPINE; DIPEPTIDES; DRUG COMBINATIONS; DRUG INTERACTIONS; HUMANS; INJECTIONS, INTRAMUSCULAR; MALE; MIDDLE AGED; MODELS, STATISTICAL; PRALIDOXIME COMPOUNDS;

EID: 78649399820     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01007.x     Document Type: Article

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