Diazepam-induced increases of synaptic efficacy in the hippocampal - medial prefrontal cortex pathway are associated with its anxiolytic-like effect in rats

Journal of Pharmacological Sciences

Volumn 114, Issue 3, 2010, Pages 341-346

  Shikanai, Hiroki ^a   Izumi, Takeshi ^a   Matsumoto, Machiko ^b   Togashi, Hiroko ^b   Yamaguchi, Taku ^a   Yoshida, Takayuki ^a   Yoshioka, Mitsuhiro ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

Anxiety; Behavior; Electrophysiology; Hippocampal medial prefrontal cortex (mPFC) pathway; Prefrontal cortex

Indexed keywords

DIAZEPAM; FLUMAZENIL;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; BRAIN REGION; COGNITION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; FEAR; HIPPOCAMPUS; MALE; MEDIAL PREFRONTAL CORTEX; NONHUMAN; OPTIMAL DRUG DOSE; PREFRONTAL CORTEX; PROMOTER REGION; RAT; SIGNAL TRANSDUCTION; SYNAPTIC EFFICACY; TRANQUILIZING ACTIVITY;

EID: 78649394528     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10182FP     Document Type: Article

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