Radiology imaging of renal structure and function by computed tomography, magnetic resonance imaging, and ultrasound

Seminars in Nuclear Medicine

Volumn 41, Issue 1, 2011, Pages 45-60

  Grenier, Nicolas ^a   Quaia, Emilio ^b   Prasad, Pottumarthi V ^c   Juillard, Laurent ^d  

^a HÔPITAL PELLEGRIN   (France)

^b UNIVERSITY OF TRIESTE   (Italy)

^c EVANSTON HOSPITAL   (United States)

^d Dpartement de Nphrologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD OXYGENATION; CELL DENSITY; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; ECHOGRAPHY; FILTRATION; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; KIDNEY STRUCTURE; MEASUREMENT; MULTIDETECTOR COMPUTED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; REVIEW;

ANIMALS; CONTRAST MEDIA; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; MAGNETIC RESONANCE IMAGING; TOMOGRAPHY, X-RAY COMPUTED; ULTRASONOGRAPHY;

EID: 78649393972     PISSN: 00012998     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semnuclmed.2010.09.001     Document Type: Review

References (132)

1. S. Qin, C.F. Caskey, and K.W. Ferrara Ultrasound contrast microbubbles in imaging and therapy: physical principles and engineering Phys Med Biol 54 2009 R27 R57
2. E. Quaia Microbubble ultrasound contrast agents: an update Eur Radiol 17 2007 1995 2008
3. V. Sboros, and M.X. Tang The assessment of microvascular flow and tissue perfusion using ultrasound imaging Proc Inst Mech Eng H 224 2010 273 290
4. D. Cosgrove, R. Eckersley, and M. Blomley Quantification of blood flow Eur Radiol 11 2001 1338 1344
5. D. Cosgrove, and C. Harvey Clinical uses of microbubbles in diagnosis and treatment Med Biol Eng Comput 47 2009 813 826
6. E. Quaia, M.J. Blomley, and S. Patel Initial observations on the effect of irradiation on the liver-specific uptake of levovist Eur J Radiol 41 2002 192 199
7. K. Yanagisawa, F. Moriyasu, and T. Miyahara Phagocytosis of ultrasound contrast agent microbubbles by Kupffer cells Ultrasound Med Biol 33 2007 318 325
8. S.B. Barnett, F. Duck, and M. Ziskin WFUMB Symposium on Safety of Ultrasound in Medicine: Conclusions and Recommendations on Biological Effects and Safety of Ultrasound Contrast Agents, 2006 Ultrasound Med Biol 33 2007 233 234
9. F. Piscaglia, and L. Bolondi The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations Ultrasound Med Biol 32 2006 1369 1375
10. P.A. Dijkmans, C.A. Visser, and O. Kamp Adverse reactions to ultrasound contrast agents: is the risk worth the benefit? Eur J Echocardiogr 6 2005 363 366
11. L.L. Kusnetzky, A. Khalid, and T.M. Khumri Acute mortality in hospitalized patients undergoing echocardiography with and without an ultrasound contrast agent: results in 18,671 consecutive studies J Am Coll Cardiol 51 2008 1704 1706
12. S.L. Mulvagh, H. Rakowski, and M.A. Vannan American Society of Echocardiography consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography J Am Soc Echocardiogr 21 2008 1179 1201 quiz: 1281
13. R. Senior, H. Becher, and M. Monaghan Contrast echocardiography: evidence-based recommendations by European Association of Echocardiography Eur J Echocardiogr 10 2009 194 212
14. J.M. Correas, P.N. Burns, and X. Lai Infusion versus bolus of an ultrasound contrast agent: in vivo doseresponse measurements of BR1 Invest Radiol 35 2000 72 79
15. J. Mari, K. Hibbs, and E. Stride An approximate nonlinear model for time gain compensation of amplitude modulated images of ultrasound contrast agent perfusion IEEE Trans Ultrason Ferroelectr Freq Control 57 2010 818 829
16. S. Mule, A. De Cesare, and O. Lucidarme Regularized estimation of contrast agent attenuation to improve the imaging of microbubbles in small animal studies Ultrasound Med Biol 34 2008 938 948
17. P. Phillips, and E. Gardner Contrast-agent detection and quantification Eur Radiol 14 suppl 8 2004 4 10
18. X. Gu, H. Zhong, and M. Wan Parametric perfusion imaging based on low-cost ultrasound platform Ultrasound Med Biol 36 2010 130 144
19. M. Wiesmann, K. Meyer, and T. Albers Parametric perfusion imaging with contrast-enhanced ultrasound in acute ischemic stroke Stroke; J Cereb Circ 35 2004 508 513 (Pubitemid 38174439)
20. K. Wei, A.R. Jayaweera, and S. Firoozan Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion Circulation 97 1998 473 483
21. T.C. Potdevin, J.B. Fowlkes, and A.P. Moskalik Analysis of refill curve shape in ultrasound contrast agent studies Med Phys 31 2004 623 632
22. T.C. Potdevin, J.B. Fowlkes, and A.P. Moskalik Refill model of rabbit kidney vasculature Ultrasound Med Biol 32 2006 1331 1338
23. O. Lucidarme, Y. Kono, and J. Corbeil Validation of ultrasound contrast destruction imaging for flow quantification Ultrasound Med Biol 29 2003 1697 1704
24. M. Arditi, P.J. Frinking, and X. Zhou A new formalism for the quantification of tissue perfusion by the destruction-replenishment method in contrast ultrasound imaging IEEE Trans Ultrason Ferroelectr Freq Control 53 2006 1118 1129
25. T.R. Porter, F. Xie, and M. Silver Real-time perfusion imaging with low mechanical index pulse inversion Doppler imaging J Am Coll Cardiol 37 2001 748 753
26. P. Meier, and K.L. Zierler On the theory of the indicator-dilution method for measurement of blood flow and volume J Appl Physiol 6 1954 731 744
27. M. Krix, F. Kiessling, and N. Farhan A multivessel model describing replenishment kinetics of ultrasound contrast agent for quantification of tissue perfusion Ultrasound Med Biol 29 2003 1421 1430
28. K. Wei, E. Le, and J.P. Bin Quantification of renal blood flow with contrast-enhanced ultrasound J Am Coll Cardiol 37 2001 1135 1140
29. K. Wei, M. Ragosta, and J. Thorpe Noninvasive quantification of coronary blood flow reserve in humans using myocardial contrast echocardiography Circulation 103 2001 2560 2565
30. K. Meyer-Wiethe, H. Cangur, and G.U. Seidel Comparison of different mathematical models to analyze diminution kinetics of ultrasound contrast enhancement in a flow phantom Ultrasound Med Biol 31 2005 93 98
31. O. Lucidarme, S. Franchi-Abella, and J.M. Correas Blood flow quantification with contrast-enhanced US: "entrance in the section" phenomenonphantom and rabbit study Radiology 228 2003 473 479
32. E. Quaia, A. Nocentini, and L. Torelli Assessment of a new mathematical model for the computation of numerical parameters related to renal cortical blood flow and fractional blood volume by contrast-enhanced ultrasound Ultrasound Med Biol 35 2009 616 627
33. N. Kishimoto, Y. Mori, and T. Nishiue Renal blood flow measurement with contrast-enhanced harmonic ultrasonography: evaluation of dopamine-induced changes in renal cortical perfusion in humans Clin Nephrol 59 2003 423 428
34. L.P. Kihm, U.P. Hinkel, and K. Michael Contrast enhanced sonography shows superior microvascular renal allograft perfusion in patients switched from cyclosporine A to everolimus Transplantation 88 2009 261 265
35. J.H. Kim, H.W. Eun, and H.J. Lee Clinical use of renal perfusion imaging by means of harmonic sonography with a microbubble contrast agent in patients after renal transplantation: preliminary study J Ultrasound Med 24 2005 755 762
36. V. Schwenger, G. Korosoglou, and U.P. Hinkel Real-time contrast-enhanced sonography of renal transplant recipients predicts chronic allograft nephropathy Am J Transplant 6 2006 609 615
37. M. Claudon, C.E. Barnewolt, and G.A. Taylor Renal blood flow in pigs: changes depicted with contrast-enhanced harmonic US imaging during acute urinary obstruction Radiology 212 1999 725 731
38. E. Quaia, S. Siracusano, and A. Palumbo Detection of focal renal perfusion defects in rabbits after sulphur hexafluoride-filled microbubble injection at low transmission power ultrasound insonation Eur Radiol 16 2006 166 172
39. G.A. Taylor, C.E. Barnewolt, and B.H. Adler Renal cortical ischemia in rabbits revealed by contrast-enhanced power Doppler sonography AJR Am J Roentgenol 170 1998 417 422
40. G.A. Taylor, C.E. Barnewolt, and M. Claudon Depiction of renal perfusion defects with contrast-enhanced harmonic sonography in a porcine model AJR Am J Roentgenol 173 1999 757 760
41. G.A. Taylor, K. Ecklund, and P.S. Dunning Renal cortical perfusion in rabbits: visualization with color amplitude imaging and an experimental microbubble-based US contrast agent Radiology 201 1996 125 129
42. M. Bertolotto, A. Martegani, and L. Aiani Value of contrast-enhanced ultrasonography for detecting renal infarcts proven by contrast enhanced CT A feasibility study Eur Radiol 18 2008 376 383
43. J.M. Correas, M. Claudon, and F. Tranquart [Contrast-enhanced ultrasonography: renal applications] J Radiol 84 2003 2041 2054
44. C.F. Hazlewood, H.E. Rorschach, and C. Lin Diffusion of water in tissues and MRI Magn Reson Med 19 1991 214 216
45. H.E. Rorschach, C. Lin, and C.F. Hazlewood Diffusion of water in biological tissues Scan Microsc Suppl 5 1991 S1 S9 discussion: S9-10
46. M.F. Muller, P. Prasad, and B. Siewert Abdominal diffusion mapping with use of a whole-body echo-planar system Radiology 190 1994 475 478
47. M.F. Muller, P.V. Prasad, and D. Bimmler Functional imaging of the kidney by means of measurement of the apparent diffusion coefficient Radiology 193 1994 711 715
48. S. Kim, M. Naik, and E. Sigmund Diffusion-weighted MR imaging of the kidneys and the urinary tract Magn Reson Imaging Clin N Am 16 2008 585 596 vii-viii
49. H.C. Thoeny, F. De Keyzer, and R.H. Oyen Diffusion-weighted MR imaging of kidneys in healthy volunteers and patients with parenchymal diseases: initial experience Radiology 235 2005 911 917
50. P.J. Basser, J. Mattiello, and D. LeBihan Estimation of the effective self-diffusion tensor from the NMR spin echo J Magn Reson B 103 1994 247 254
51. S. Mori, and P.C. van Zijl Fiber tracking: principles and strategiesa technical review NMR Biomed 15 2002 468 480
52. S.T. Engelter, S.G. Wetzel, and L.H. Bonati The clinical significance of diffusion-weighted MR imaging in stroke and TIA patients Swiss Med Wkly 138 2008 729 740
53. S.F. Carbone, E. Gaggioli, and V. Ricci Diffusion-weighted magnetic resonance imaging in the evaluation of renal function: a preliminary study Radiol Med 112 2007 1201 1210
54. N.H. Afdhal, and D. Nunes Evaluation of liver fibrosis: a concise review Am J Gastroenterol 99 2004 1160 1174
55. L. Lu, G. Lee, and V. Gulani Diffusion tensor imaging as a biomarker of diabetic nephropathy 2010 International Society of Magnetic Resonance in Medicine Stockholm, Sweden 97
56. M. Brezis, and S. Rosen Hypoxia of the renal medullaits implications for disease N Engl J Med 332 1995 647 655
57. K.U. Eckardt, W.M. Bernhardt, and A. Weidemann Role of hypoxia in the pathogenesis of renal disease Kidney Int Suppl 99 2005 S46 S51
58. J.T. Norman, and L.G. Fine Intrarenal oxygenation in chronic renal failure Clin Exp Pharmacol Physiol 33 2006 989 996
59. F.H. Epstein, Y. Agmon, and M. Brezis Physiology of renal hypoxia Ann NY Acad Sci 718 1994 72 81 discussion: 81-72
60. P.M. Matthews, and P. Jezzard Functional magnetic resonance imaging J Neurol Neurosurg Psychiatry 75 2004 6 12
61. P. Rajagopalan, K.R. Krishnan, and T.J. Passe Magnetic resonance imaging using deoxyhemoglobin contrast versus positron emission tomography in the assessment of brain function Prog Neuropsychopharmacol Biol Psychiatry 19 1995 351 366
62. K. Ugurbil, X. Hu, and W. Chen Functional mapping in the human brain using high magnetic fields Philos Trans R Soc Lond B Biol Sci 354 1999 1195 1213
63. J.F. Dunn, and H.M. Swartz Blood oxygenation Heterogeneity of hypoxic tissues monitored using bold MR imaging Adv Exp Med Biol 428 1997 645 650
64. P.V. Prasad, Q. Chen, and J.W. Goldfarb Breath-hold R2 (*) mapping with a multiple gradient-recalled echo sequence: application to the evaluation of intrarenal oxygenation J Magn Reson Imaging 7 1997 1163 1165
65. P.V. Prasad, R.R. Edelman, and F.H. Epstein Noninvasive evaluation of intrarenal oxygenation with BOLD MRI Circulation 94 1996 3271 3275
66. A. Priatna, F.H. Epstein, and K. Spokes Evaluation of changes in intrarenal oxygenation in rats using multiple gradient-recalled echo (mGRE) sequence J Magn Reson Imaging 9 1999 842 846
67. M. Brezis, Y. Agmon, and F.H. Epstein Determinants of intrarenal oxygenation I. Effects of diuretics Am J Physiol 267 1994 F1059 F1062
68. F.H. Epstein, A. Veves, and P.V. Prasad Effect of diabetes on renal medullary oxygenation during water diuresis Diabetes Care 25 2002 575 578
69. 2 during water diuresis as evaluated by blood oxygenation level-dependent magnetic resonance imaging: effects of aging and cyclooxygenase inhibition Kidney Int 55 1999 294 298
70. S.M. Tumkur, A.T. Vu, and L.P. Li Evaluation of intra-renal oxygenation during water diuresis: a time-resolved study using BOLD MRI Kidney Int 70 2006 139 143
71. Lin JL, Li L, Schnitzer T,, et al. Intra-renal oxygenation in Rat kidneys during water-loading: effects of COX inhibition and NO donation. J Magn Reson Imaging in press
72. M.N. Muscara, and J.L. Wallace COX-inhibiting nitric oxide donors (CINODs): potential benefits on cardiovascular and renal function Cardiovasc Hematol Agents Med Chem 4 2006 155 164
73. L. Li, P. Storey, and D. Kim Kidneys in hypertensive rats show reduced response to nitric oxide synthase inhibition as evaluated by BOLD MRI J Magn Reson Imaging 17 2003 671 675
74. L.P. Li, B.S. Li, and P. Storey Effect of free radical scavenger (tempol) on intrarenal oxygenation in hypertensive rats as evaluated by BOLD MRI J Magn Reson Imaging 21 2005 245 248
75. L.P. Li, L. Ji, and E.A. Santos Effect of nitric oxide synthase inhibition on intrarenal oxygenation as evaluated by blood oxygenation level-dependent magnetic resonance imaging Invest Radiol 44 2009 67 73
76. L. Juillard, L.O. Lerman, and D.G. Kruger Blood oxygen level-dependent measurement of acute intra-renal ischemia Kidney Int 65 2004 944 950
77. M. Ries, F. Basseau, and B. Tyndal Renal diffusion and BOLD MRI in experimental diabetic nephropathy Blood oxygen level-dependent J Magn Reson Imaging 17 2003 104 113
78. S.C. Textor, J.F. Glockner, and L.O. Lerman The use of magnetic resonance to evaluate tissue oxygenation in renal artery stenosis J Am Soc Nephrol 19 2008 780 788
79. C.M. Cheung, A.E. Shurrab, and D.L. Buckley MR-derived renal morphology and renal function in patients with atherosclerotic renovascular disease Kidney Int 69 2006 715 722
80. H.C. Thoeny, T.M. Kessler, and S. Simon-Zoula Renal oxygenation changes during acute unilateral ureteral obstruction: assessment with blood oxygen level-dependent MR imaginginitial experience Radiology 247 2008 754 761
81. J. Breza, and P. Navratil Renal transplantation in adults BJU Int 84 1999 216 223
82. A.O. Ojo, R.A. Wolfe, and P.J. Held Delayed graft function: risk factors and implications for renal allograft survival Transplantation 63 1997 968 974
83. F.J. Gainza, I. Minguela, and I. Lopez-Vidaur Evaluation of complications due to percutaneous renal biopsy in allografts and native kidneys with color-coded Doppler sonography Clin Nephrol 43 1995 303 308
84. A. Preda, L.C. Van Dijk, and J.A. Van Oostaijen Complication rate and diagnostic yield of 515 consecutive ultrasound-guided biopsies of renal allografts and native kidneys using a 14-gauge Biopty gun Eur Radiol 13 2003 527 530
85. A. Djamali, E.A. Sadowski, and R.J. Muehrer BOLD-MRI assessment of intrarenal oxygenation and oxidative stress in patients with chronic kidney allograft dysfunction Am J Physiol Ren Physiol 292 2007 F513 F522
86. F. Han, W. Xiao, and Y. Xu The significance of BOLD MRI in differentiation between renal transplant rejection and acute tubular necrosis Nephrol Dial Transplant 23 2008 2666 2672
87. P. Malvezzi, I. Bricault, and N. Terrier Evaluation of intrarenal oxygenation by blood oxygen level-dependent magnetic resonance imaging in living kidney donors and their recipients: preliminary results Transplant Proc 41 2009 641 644
88. H.C. Thoeny, D. Zumstein, and S. Simon-Zoula Functional evaluation of transplanted kidneys with diffusion-weighted and BOLD MR imaging: initial experience Radiology 241 2006 812 821
89. A. Prigent Monitoring renal function and limitations of renal function tests Semin Nucl Med 38 2008 32 46
90. W.K. Rohrschneider, J. Hoffend, and K. Becker Combined static-dynamic MR urography for the simultaneous evaluation of morphology and function in urinary tract obstruction I. Evaluation of the normal status in an animal model Pediatr Radiol 30 2000 511 522 (Pubitemid 30609567)
91. W.K. Rohrschneider, K. Becker, and J. Hoffend Combined static-dynamic MR urography for the simultaneous evaluation of morphology and function in urinary tract obstruction II. Findings in experimentally induced ureteric stenosis Pediatr Radiol 30 2000 523 532 (Pubitemid 30609568)
92. W.K. Rohrschneider, S. Haufe, and M. Wiesel Functional and morphologic evaluation of congenital urinary tract dilatation by using combined static-dynamic MR urography: findings in kidneys with a single collecting system Radiology 224 2002 683 694
93. M. Pedersen, Y. Shi, and P. Anderson Quantitation of differential renal blood flow and renal function using dynamic contrast-enhanced MRI in rats Magn Reson Med 51 2004 510 517
94. P.L. Choyke, H.A. Austin, and J.A. Frank Hydrated clearance of gadolinium-DTPA as a measurement of glomerular filtration rate Kidney Int 41 1992 1595 1598
95. A. Boss, P. Martirosian, and M. Gehrmann Quantitative assessment of glomerular filtration rate with MR gadolinium slope clearance measurements: a phase I trial Radiology 242 2007 783 790
96. I. Mendichovszky, M. Pedersen, and J. Frokiaer How accurate is dynamic contrast-enhanced MRI in the assessment of renal glomerular filtration rate? A critical appraisal J Magn Reson Imaging 27 2008 925 931
97. H. Rusinek, V.S. Lee, and G. Johnson Optimal dose of Gd-DTPA in dynamic MR studies Magn Reson Med 46 2001 312 316
98. B.D. de Senneville, I.A. Mendichovszky, and S. Roujol Improvement of MRI-functional measurement with automatic movement correction in native and transplanted kidneys J Magn Reson Imaging 28 2008 970 978
99. N. Michoux, J.P. Vallee, and A. Pechere-Bertschi Analysis of contrast-enhanced MR images to assess renal function Magma 19 2006 167 179
100. L. Bokacheva, H. Rusinek, and J.L. Zhang Assessment of renal function with dynamic contrast-enhanced MR imaging Magn Reson Imaging Clin N Am 16 2008 597 611 viii
101. N. Grenier, I. Mendichovszky, and B.D. de Senneville Measurement of glomerular filtration rate with magnetic resonance imaging: principles, limitations, and expectations Semin Nucl Med 38 2008 47 55
102. C.S. Patlak, R.G. Blasberg, and J.D. Fenstermacher Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data J Cereb Blood Flow Metab 3 1983 1 7
103. L. Annet, L. Hermoye, and F. Peeters Glomerular filtration rate: assessment with dynamic contrast-enhanced MRI and a cortical-compartment model in the rabbit kidney J Magn Reson Imaging 20 2004 843 849
104. L. Hermoye, L. Annet, and P. Lemmerling Calculation of the renal perfusion and glomerular filtration rate from the renal impulse response obtained with MRI Magn Reson Med 51 2004 1017 1025
105. M. Pedersen, T. Dissing, and D. Deding MR renography based on contrast-enhanced T1-mapping Medicine ISfMRi (ed) 2005 International Society for Magnetic Resonance in Medicine Miami 526
106. N. Hackstein, H. Cengiz, and W.S. Rau Contrast media clearance in a single kidney measured on multiphasic helical CT: results in 50 patients without acute renal disorder AJR Am J Roentgenol 178 2002 111 118
107. N. Hackstein, J. Heckrodt, and W.S. Rau Measurement of single-kidney glomerular filtration rate using a contrast-enhanced dynamic gradient-echo sequence and the Rutland-Patlak plot technique J Magn Reson Imaging 18 2003 714 725 (Pubitemid 37467273)
108. V.S. Lee, H. Rusinek, and L. Bokacheva Renal function measurements from MR renography and a simplified multicompartmental model Am J Physiol 292 2007 F1548 F1559
109. D. Laurent, K. Poirier, and J. Wasvary Effect of essential hypertension on kidney function as measured in rat by dynamic MRI Magn Reson Med 47 2002 127 134
110. V.S. Lee, H. Rusinek, and M.E. Noz Dynamic three-dimensional MR renography for the measurement of single kidney function: initial experience Radiology 227 2003 289 294
111. C.L. Dumoulin, M.H. Buonocore, and L.R. Opsahl Noninvasive measurement of renal hemodynamic functions using gadolinium enhanced magnetic resonance imaging Magn Reson Med 32 1994 370 378
112. E.R. Niendorf, G.E. Santyr, and P.C. Brazy Measurement of Gd-DTPA dialysis clearance rates by using a look-locker imaging technique Magn Reson Med 36 1996 571 578
113. E.R. Niendorf, T.M. Grist, and R. Frayne Rapid measurement of Gd-DTPA extraction fraction in a dialysis system using echo-planar imaging Med Phys 24 1997 1907 1913
114. E.R. Niendorf, T.M. Grist, and F.T. Lee Jr Rapid in vivo measurement of single-kidney extraction fraction and glomerular filtration rate with MR imaging Radiology 206 1998 791 798
115. L.O. Lerman, M.D. Bentley, and M.R. Bell The effect of a low-osmolar radiographic contrast medium on in vivo and postmortem renal size Invest Radiol 26 1991 992 997
116. E. Daghini, L. Juillard, and J.A. Haas Comparison of mathematic models for assessment of glomerular filtration rate with electron-beam CT in pigs Radiology 242 2007 417 424
117. J.D. Krier, E.L. Ritman, and Z. Bajzer Noninvasive measurement of concurrent single-kidney perfusion, glomerular filtration, and tubular function Am J Physiol Ren Physiol 281 2001 F630 F638
118. M.D. Bentley, L.O. Lerman, and E.A. Hoffman Measurement of renal perfusion and blood flow with fast computed tomography Circ Res 74 1994 945 951
119. L.O. Lerman, R.S. Schwartz, and J.P. Grande Noninvasive evaluation of a novel swine model of renal artery stenosis J Am Soc Nephrol 10 1999 1455 1465
120. A.R. Chade, M. Rodriguez-Porcel, and J.P. Grande Distinct renal injury in early atherosclerosis and renovascular disease Circulation 106 2002 1165 1171
121. A.R. Chade, J.D. Krier, and M. Rodriguez-Porcel Comparison of acute and chronic antioxidant interventions in experimental renovascular disease Am J Physiol Ren Physiol 286 2004 F1079 F1086
122. A. Feldstein, J.D. Krier, and M.H. Sarafov In vivo renal vascular and tubular function in experimental hypercholesterolemia Hypertension 34 1999 859 864
123. J.C. Romero, and L.O. Lerman Novel noninvasive techniques for studying renal function in man Semin Nephrol 20 2000 456 462
124. L.I. Pelaez, L.A. Juncos, and J.M. Stulak Non-invasive evaluation of bilateral renal regional blood flow and tubular dynamics during acute unilateral ureteral obstruction Nephrol Dial Transplant 20 2005 83 88
125. N.B. Itano, L.E. Sherrill, and L.O. Lerman Electron beam computerized tomography assessment of in vivo single kidney glomerular filtration rate and tubular dynamics during chronic partial unilateral ureteral obstruction in the pig J Urol 166 2001 2530 2535
126. L.O. Lerman, S.J. Taler, and S.C. Textor Computed tomography-derived intrarenal blood flow in renovascular and essential hypertension Kidney Int 49 1996 846 854
127. Y. Tsushima, M.J. Blomley, and K. Okabe Determination of glomerular filtration rate per unit renal volume using computerized tomography: correlation with conventional measures of total and divided renal function J Urol 165 2001 382 385
128. N. Hackstein, J. Bauer, and E.W. Hauck Measuring single-kidney glomerular filtration rate on single-detector helical CT using a two-point Patlak plot technique in patients with increased interstitial space AJR Am J Roentgenol 181 2003 147 156
129. N. Hackstein, C. Wiegand, and W.S. Rau Glomerular filtration rate measured by using triphasic helical CT with a two-point Patlak plot technique Radiology 230 2004 221 226
130. Y. Tsushima Functional CT of the kidney Eur J Radiol 30 1999 191 197
131. L.O. Lerman, A.L. Flickinger, and P.F. Sheedy 2nd Reproducibility of human kidney perfusion and volume determinations with electron beam computed tomography Invest Radiol 31 1996 204 210
132. A.J. Einstein, M.J. Henzlova, and S. Rajagopalan Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography JAMA 298 2007 317 323