Antinociception effect and mechanisms of Campanula punctata extract in the mouse

Korean Journal of Physiology and Pharmacology

Volumn 14, Issue 5, 2010, Pages 285-289

  Park, Soo Hyun ^a   Sim, Yun Beom ^a   Lim, Soon Sung ^a   Kim, Jin Kyu ^a   Lee, Jin Koo ^a   Suh, Hong Won ^a  

^a Hallym University   (South Korea)

Author keywords

2 adrenoceptor; Anti nociception; Campanula punctata; Inflammatory pain

Indexed keywords

ACETIC ACID; ALPHA 2 ADRENERGIC RECEPTOR; ANALGESIC AGENT; CAMPANULA PUNCTATA EXTRACT; METHYSERGIDE; NALOXONE; OPIATE RECEPTOR; PLANT EXTRACT; SAPONIN; SEROTONIN RECEPTOR; SUBSTANCE P; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CAMPANULA PUNCTATA; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENTIATION; HOT PLATE TEST; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PAIN; TAIL FLICK TEST; WRITHING TEST;

EID: 78649371082     PISSN: 12264512     EISSN: None     Source Type: Journal    
DOI: 10.4196/kjpp.2010.14.5.285     Document Type: Article

References (21)

1. Kathleen N, Brenzel ED. Sunset Western Garden Book. 6th ed. Sunset Publishing Corporation; 1995. 606-607 p.
2. Shin CY, Lee WJ, Lee EB, Choi EY, Ko KH. Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters. Planta Med. 2002;68:221-225.
3. Hylden JL, Wilcox GL. Intrathecal morphine in mice: a new technique. Eur J Pharmacol. 1980;67:313-316.
4. Hylden JL, Wilcox GL. Intrathecal substance P elicits a caudally- directed biting and scratching behavior in mice. Brain Reserch. 1981;217:212-215.
5. D'Amour FE, Smith DL. A method for determining loss of pain sensation. J Pharmacol Exp Ther. 1941;72:74-79.
6. Eddy NB, Leimbach D. Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines. J Pharmacol Exp Ther. 1953;107:385-393.
7. Koster R, Anderson M, Beer EJ. Acetic acid for analgesic screening. Federal Proceeding. 1959;18:412.
8. Choi SS, Han KJ, Lee JK, Lee HK, Han EJ, Kim DH, Suh HW. Antinociceptive mechanisms of orally administered decursinol in the mouse. Life Sciences. 2003;13:471-485.
9. Park SH, Sim YB, Choi SM, Seo YJ, Kwon MS, Lee JK, Suh HW. Antinociceptive Profiles and Mechanisms of Orally Administered Vanillin in the Mice. Arch Pharm Res. 2009;32:1643-1649.
10. Suh HW, Song DK, Son KH, Wie MB, Lee KH, Jung KY, Do JC, Kim YH. Antinociceptive mechanisms of dipsacus saponin C administered intracerebroventricularly in the mouse. General Pharmacology. 1996;27:1167-1172.
11. Suh HW, Song DK, Kim YH. Differntial effects of adenosine receptor antagonist injected intrathecally on antinociception induced by morphine and beta-endorphin administered intra-cerebroventricularly in the mouse. Neuropeptides. 1997;31:339-344.
12. Suh HW, Chung KM, Kim YH, Huh SO, Song DK. Effect of histamine receptor antagonists injected intrathecally on antinociception induced by opioids administered intracerebroventricularly in the mouse. Neuropeptides. 1999;33:121-129.
13. Chapman CR, Casey KL, Dubner R, Foley KM, Gracely RH, Reading AE. Pain measurement: an overview. Pain. 1985;22:1-31.
14. Grumbach L. The prediction of analgesic activity in man by animal testing. In: Knighton RS, Dumke PR, eds. Pain. Boston: Little Brown and Co; 1966. 163-182 p.
15. Vyklicky L. The techniques for the study of pain in animals. In: Bonica JJ, Liebeskind JC, Albe-Fessard DG, eds. Adv Pain Res Ther. Vol. 3. New York: Raven. 1979. 727-745 p.
16. Cumberbatch MJ, Herrero JH, Headley PM. Exposure of rat spinal neurons to NMDA, AMPA and kainate produces only short-term enhancements of responses to noxious and non-noxious stimuli. Neuroscience Letters. 1994;181:98-102.
17. Schmauss C, Yaksh TL. In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical and cutaneous thermal stimuli in the rat. J Pharmacol Exp Ther. 1984;228:1-12.
18. Yaksh TL. Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinpciceptive effects of morphine in the periaqueductal gray. Brain Resesrch. 1979;160:180-185.
19. Yaksh TL. Multiple opioid receptor systems in brain and spinal cord: Part I. Eur J Anaesthesiol. 1984;1:171-199.
20. Jensen TS, Yaksh TL. Spinal monoamine and opiate systems partly mediate the antinociceptive effects produced by glutamate at brainstem sites. Brain Research. 1984;321:287-297.
21. Wigdor S, Wilcox GL. Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways. Journal of pharmacology and Experimental Therapeutics. 1987;242:90-95.