Translational research at community health centers: Challenges and successes in recruiting and retaining low-income latino patients with type 2 diabetes into a randomized clinical trial

Diabetes Educator

Volumn 36, Issue 5, 2010, Pages 733-749

  Rosal, Milagros C ^a   White, Mary Jo ^a   Borg, Amy ^a   Scavron, Jeffrey ^b   Candib, Lucy ^c   Ockene, Ira ^a   Magner, Robert ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b Brightwood Health Center   (United States)

^c Family Health Center of Worcester   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLATED HEMOGLOBIN;

ADULT; ARTICLE; ATTITUDE TO HEALTH; ECONOMICS; HEALTH CENTER; HISPANIC; HUMAN; INTERVIEW; METABOLISM; METHODOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; PATIENT SELECTION; POVERTY; RANDOMIZED CONTROLLED TRIAL (TOPIC); SELF CARE; TRANSLATIONAL RESEARCH; UNITED STATES;

ADULT; ATTITUDE TO HEALTH; COMMUNITY HEALTH CENTERS; DIABETES MELLITUS, TYPE 2; HEMOGLOBIN A, GLYCOSYLATED; HISPANIC AMERICANS; HUMANS; INTERVIEWS AS TOPIC; MASSACHUSETTS; PATIENT SELECTION; POVERTY; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SELF CARE; TRANSLATIONAL RESEARCH; YOUNG ADULT;

EID: 78649365055     PISSN: 01457217     EISSN: 15546063     Source Type: Journal    
DOI: 10.1177/0145721710380146     Document Type: Article

References (73)

1. US Department of Health and Human Services, Centers for Disease Control and Prevention. Age-adjusted prevalence of diagnosed diabetes by race/ethnicity and sex in the United States, 1980-2005. Available at: www.cdc.gov/diabetes/statistics/prev/ national/figraceethsex.htm. Accessed January 21, 2010.
2. US Census Bureau. Annual estimates of the population by sex, race, and Hispanic or Latino origin for the United States: April 1, 2000 to July 1, 2006. Available at: www.census.gov/popest/national/asrh/NC-EST2006-srh.html. Accessed January 21, 2010.
3. National Center for Health Statistics. Early release of selected estimates based on data from the January-September 2006 National Health Interview Survey. Available at: http://www. cdc.gov/nchs/about/major/nhis/released200703.htm. Accessed January 12, 2010.
4. Centers for Disease Control and Prevention. Self-reported prevalence of diabetes among Hispanics: United States, 1994-1997. MMWR. 1999;48:8-12.
5. Harris MI, Klein R, Cowie CC, Rowland M, Byrd-Holt DD. Is the risk of diabetic retinopathy greater in non-Hispanic blacks and Mexican Americans than in non-Hispanic whites with type 2 diabetes? A U.S. population study. Diabetes Care. 1998; 21:1230-1235.
6. Franklin GM, Kahn LB, Baxter J, Marshall JA, Hamman RF. Sensory neuropathy in non-insulin-dependent diabetes mellitus: the San Luis Valley Diabetes Study. Am J Epidemiol. 1990;131:633-643.
7. Agency for Healthcare Research and Quality. National Healthcare Disparities Report, 2006. Rockville, MD: Agency for Healthcare Research and Quality; 2006. Available at: http://www.ahrq.gov/qual/nhdr06/nhdr06.htm. Accessed January 12, 2010.
8. National Institute of Diabetes and Digestive and Kidney Diseases, National Diabetes Information Clearinghouse (NDIC). National diabetes statistics. Available at: http://diabetes.niddk.nih.gov/dm/pubs/statistics/index.htm. Accessed January 12, 2010.
9. US Department of Health and Human Services, Office of Minority Research. Diabetes and Hispanic Americans. Available at: http://www.omhrc.gov/templates/content.aspx?lvl=2&lvllD= 54&ID=3324. Accessed December 10, 2009.
10. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329: 977-986.
11. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837-853.
12. Norris SL, Engelgau MM, Narayan KM. Effectiveness of self-management training in type 2 diabetes: a systematic review of randomized controlled trials. Diabetes Care. 2001;24:561-587.
13. Brown SA, Garcia AA, Kouzekanani K, Hanis CL. Culturally competent diabetes self-management education for Mexican Americans: the Starr County border health initiative. Diabetes Care. 2002;25:259-268.
14. Lorig K, Ritter PL, Villa F, Piette JD. Spanish diabetes self-management with and without automated telephone reinforcement: two randomized trials. Diabetes Care. 2008; 31:408-414.
15. Rosal MC, Olendzki B, Reed GW, Gumieniak O, Scavron J, Ockene IS. Diabetes self-management among low-income Spanish speaking patients: a pilot study. Ann Behav Med. 2005;29:225-235.
16. Mauldon M, Melkus GD, Cagganello M. Tomando Control: a culturally appropriate diabetes education program for Spanish-speaking individuals with type 2 diabetes mellitus. Evaluation of a pilot project. Diabetes Educ. 2006;32:751-760.
17. Centers for Disease Control and Prevention, National Center for Health Statistics. Age-adjusted percentage of civilian, noninstitutionalized population with diagnosed diabetes, Hispanics, United States, 1980-2007. Available at: http://www.ced.gov/diabetes/ statistics/prev/national/figbyhispanic.htm. Accessed March 31, 2010.
18. Flegal KM, Ezzati TM, Harris MI. Prevalence of diabetes in Mexican Americans, Cubans, and Puerto Ricans from the Hispanic health and nutrition examination survey 1982-1984. Diabetes Care. 1991;14(7 Suppl):528-538.
19. Lemon SC, Zapka JG, Estabrook B, Benjamin E. Challenges to research in urban community health centers. Am J Public Health. 2006;96:626-628.
20. Handley MA, Hammer H, Schillinger D. Navigating the terrain between research and practice: a Collaborative Research Network (CRN) case study in diabetes research. J Am Board Fam Med. 2006;19:85-92.
21. Piatt GA, Orchard TJ, Emerson S. Translating the chronic care model into the community: results from a randomized controlled trial of a multifaceted diabetes care intervention. Diabetes Care. 2006;29:811-817.
22. Frayne SM, Burns RB, Hardt EJ, Rosen AK, Moskowitz MA. The exclusion of non-English-speaking persons from research. J Gen Intern Med. 1996;11:39-43.
23. Durant RW, Davis RB, St George M, Williams IC, Blumenthal C, Corbie-Smith GM. Participation in research studies: factors associated with failing to meet minority recruitment goals. Ann Epidemiol. 2007;17:634-642.
24. Centers for Disease Control and Prevention, Department of Health and Human Services. Diabetes data and trends. Available at: http:www.cdc.gov/diabetes/statistics/prev/national/. Accessed March 31 2010.
25. Surani S, Aguillar R, Komari V, Surani A, Subramanian S. Influence of Hispanic ethnicity in prevalence of diabetes mellitus in sleep apnea and relationship to sleep phase. Postgrad Med. 2009;121:108-112.
26. Link CL, McKinlay JB. Disparities in the prevalence of diabetes: is it race/ethnicity or socioeconomic status? Results from the Boston Area Community Health (BACH) survey. Ethn Dis. 2009;19:288-292.
27. Bryson CL, Ross HJ, Boyko EJ, Young BA. Racial and ethnic variations in albuminuria in the US Third National Health and Nutrition Examination Survey (NHANES III) population: associations with diabetes and level of CKD. Am J Kidney Dis. 2006; 48:720-726.
28. Gross R, Olfson M, Gameroff MJ. Depression and glycemic control in Hispanic primary care patients with diabetes. J Gen Intern Med. 2005;20:460-466.
29. Trief PM, Morin PC, Izquierdo R. Depression and glycemic control in elderly ethnically diverse patients with diabetes: the IDEATel project. Diabetes Care. 2006; 29:830-835.
30. McCarthy CR. Historical background of clinical trials involving women and minorities. Acad Med. 1994;69:695-698.
31. Rosal MC, Benjamin EM, Pekow PS, Lemon SC, von Goeler D. Opportunities and challenges for diabetes prevention at two community health centers. Diabetes Care. 2008; 31:247-254.
32. Blumenthal DS, Sung J, Coates R, Williams J, Liff J. Recruitment and retention of subjects for a longitudinal cancer prevention study in an inner-city black community. Health Serv Res. 1995;30(1 Pt 2):197-205.
33. UyBico SJ, Pavel S, Gross CP. Recruiting vulnerable populations into research: a systematic review of recruitment interventions. J Gen Intern Med. 2007;22:852-863.
34. Corbie-Smith GM. Minority recruitment and participation in health research. N C Med J. 2004; 65:385-387.
35. Bruner DW, Jones M, Buchanan D, Russo J. Reducing cancer disparities for minorities: a multidisciplinary research agenda to improve patient access to health systems, clinical trials, and effective cancer therapy. J Clin Oncol. 2006;24:2209-2215.
36. Blumenthal DS, Lukomnik JE, Hawkins DR, Jr. A proposal to provide care to the uninsured through a network of community health centers. J Health Care Poor Underserved. 1993;4:272-279.
37. Davis SK, Collins KS, Hall A., Community health centers in a changing U.S. health care system, Policy Brief Commonw Fund. 1999;(300):1-13.
38. US Department of Health and Human Services, Health Resources and Services Administration. Bureau of Primary Health Care. America's health centers: models for quality primary health care. Available at: http://bphc.hrsa.gov/chc/charts/healthcenters.htm. Accessed January 8 2010.
39. Rosal MC, White MJ, Restrepo A. Design and methods for a randomized clinical trial of a diabetes self-management intervention for low-income Latinos: Latinos en Control. BMC Med Res Methodol. 2009;9:81.
40. Miller WR, Rollnick S. Motivational Interviewing: Preparing People for Change. 2nd ed. New York: Guilford Press; 2002.
41. Moreno-John G, Gachie A, Fleming CM. Ethnic minority older adults participating in clinical research: developing trust. J Aging Health. 2004;16(5 Suppl):93S-123S.
42. Mullins CD, Blatt L, Gbarayor CM, Yang HW, Baquet C. Health disparities: a barrier to high-quality care. Am J Health Syst Pharm. 2005;62:1873-1882.
43. Baquet CR, Commiskey P, Daniel Mullins C, Mishra SI. Recruitment and participation in clinical trials: socio-demographic, rural/urban, and health care access predictors. Cancer Detect Prev. 2006;30:24-33.
44. Newman PA, Duan N, Roberts KJ. HIV vaccine trial participation among ethnic minority communities: barriers, motivators, and implications for recruitment. J Acquir Immune Defic Syndr. 2006;41:210-217.
45. Bolen S, Tilburt J, Baffi C. Defining "success" in recruitment of underrepresented populations to cancer clinical trials: moving toward a more consistent approach. Cancer. 2006;106:1197-1204.
46. Gross CP, Herrin J, Wong N, Krumholz HM. Enrolling older persons in cancer trials: the effect of sociodemographic, protocol, and recruitment center characteristics. J Clin Oncol. 2005;23:4755-4763.
47. Adams-Campbell LL, Ahaghotu C, Gaskins M. Enrollment of African Americans onto clinical treatment trials: study design barriers. J Clin Oncol. 2004;22:730-734.
48. Fitzgibbon ML, Prewitt TE, Blackman LR. Quantitative assessment of recruitment efforts for prevention trials in two diverse black populations. Prev Med. 1998;27:838-845.
49. Vollmer WM, Osborne ML, Hertert S, Buist AS. Recruiting hard-to-reach subjects: is it worth the effort? Control Clin Trials. 1994;15:154-159.
50. Forrest CB, Whelan EM. Primary care safety-net delivery sites in the United States: a comparison of community health centers, hospital outpatient departments, and physicians'; offices. JAMA. 2000;284:2077-2083.
51. Comis RL, Miller JD, Aldige CR, Krebs L, Stoval E. Public attitudes toward participation in cancer clinical trials. J Clin Oncol. 2003;21:830-835.
52. Glasgow RE, Nutting PA, Toobert DJ. Effects of a brief computer-assisted diabetes self-management intervention on dietary, biological and quality-of-life outcomes. Chronic Illness. 2006; 2:27-38.
53. Gerber BS, Brodsky IG, Lawless KA. Implementation and evaluation of a low-literacy diabetes education computer multimedia application. Diabetes Care. 2005;28:1574-1580.
54. Feathers JT, Kieffer EC, Palmisano G. The development, implementation, and process evaluation of the REACH Detroit Partnership's Diabetes Lifestyle Intervention. Diabetes Educ. 2007;33:509-520.
55. Corbie-Smith G, Williams IC, Blumenthal C, Dorrance J, Estroff SE, Henderson G. Relationships and communication in minority participation in research: multidimensional and multidirectional. J Natl Med Assoc. 2007;99:489-498.
56. Fouad MN, Partridge E, Green BL. Minority recruitment in clinical trials: a conference at Tuskegee, researchers and the community. Ann Epidemiol. 2000;10(8 Suppl):S35-S40.
57. Murthy VH, Krumholz HM, Gross CP. Participation in cancer clinical trials: race-sex-, and age-based disparities. JAMA. 2004;291:2720-2726.
58. Corbie-Smith G, Thomas SB, Williams MV, Moody-Ayers S. Attitudes and beliefs of African Americans toward participation in medical research. J Gen Intern Med. 1999; 14:537-546.
59. Shavers VL, Lynch CF, Burmeister LF. Racial differences in factors that influence the willingness to participate in medical research studies. Ann Epidemiol. 2002; 12:248-256.
60. Roberson NL. Clinical trial participation: viewpoints from racial/ ethnic groups. Cancer. 1994;74(9 Suppl):2687-2691.
61. Moorman PG, Newman B, Millikan RC, Tse CK, Sandler DP. Participation rates in a case-control study: the impact of age, race, and race of interviewer. Ann Epidemiol. 1999; 9:188-195.
62. Glasgow RE, Nelson CC, Kearney KA. Reach, engagement, and retention in an Internet-based weight loss program in a multi-site randomized controlled trial. J Med Internet Res. 2007;9:e11.
63. Harris KJ, Ahluwalia JS, Catley D, Okuyemi KS, Mayo MS, Resnicow K. Successful recruitment of minorities into clinical trials: the Kick It at Swope project. Nicotine Tob Res. 2003;5:575-584.
64. Gallagher-Thompson D, Rabinowitz Y, Tang PC. Recruiting Chinese Americans for dementia caregiver intervention research: suggestions for success. Am J Geriatr Psychiatry. 2006;14:676-683.
65. Thoolen B, de Ridder D, Bensing J, Gorter K, Rutten G. Who participates in diabetes self-management interventions? Issues of recruitment and retainment. Diabetes Educ. 2007;33:465-474.
66. Glasgow RE, Lichtenstein E, Marcus AC. Why don't we see more translation of health promotion research to practice? Rethinking the efficacy-to-effectiveness transition. Am J Public Health. 2003;93:1261-1267.
67. Unson CG, Ohannessian C, Kenyon L, Case A, Reisine S, Prestwood K. Barriers to eligibility and enrollment among older women in a clinical trial on osteoporosis: effects of ethnicity and SES. J Aging Health. 2004;16:426-443.
68. Conn VS, Hafdahl AR, Mehr DR, LeMaster JW, Brown SA, Nielsen PJ. Metabolic effects of interventions to increase exercise in adults with type 2 diabetes. Diabetologia. 2007;50: 913-921.
69. Gary TL, Batts-Turner M, Bone LR. A randomized controlled trial of the effects of nurse case manager and community health worker team interventions in urban African-Americans with type 2 diabetes. Control Clin Trials. 2004;25:53-66.
70. Samuel-Hodge CD, Keyserling TC, France R. A church-based diabetes self-management education program for African Americans with type 2 diabetes. Prev Chronic Dis. 2006; 3:A93.
71. Miller WR, Rollnick S. Motivational Interviewing: Preparing People to Change Addictive Behavior. New York: Guilford Press; 1991.
72. Goldberg JH, Kiernan M. Innovative techniques to address retention in a behavioral weight-loss trial. Health Educ Res. 2005;20:439-447.
73. Marmor JK, Oliveria SA, Donahue RP. Factors encouraging cohort maintenance in a longitudinal study. J Clin Epidemiol. 1991;44:531-535.