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Volumn 45, Issue 12, 2010, Pages 6120-6126

Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide

(1) Thangamani, Arumugam a,b

a INDIAN INSTITUTE OF TECHNOLOGY GUWAHATI (India)

b KARPAGAM UNIVERSITY (India)

Author keywords

Antibacterial activity; Antifungal activity; Azomethine ylide; Cycloaddition; Oxindolopyrrolizidines; Spiroheterocycle

Indexed keywords

1' (3 BROMOPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 CHLOROPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 FLUOROPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 METHOXYPHENYL) 2 (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 METHOXYPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 METHYLPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 N,N DIMETHYLAMINOPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (4 NITROPHENYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; 1' (ARYL) 2' (2 THIENYLCARBONYL) SPIRO (3H INDOLE 3,3' PYRROLIZIN) 2 ONE DERIVATIVE; AMPHOTERICIN B; AZOMETHINE YLIDE; PYRROLIZIDINE DERIVATIVE; SPIROOXINDOLOPYRROLIZIDINE DERIVATIVE; STREPTOMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CYCLOADDITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; RHIZOPUS; SALMONELLA TYPHI; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; AZO COMPOUNDS; CANDIDA ALBICANS; CYCLIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROBIAL SENSITIVITY TESTS; PYRROLIDINES; RHIZOPUS; SALMONELLA TYPHI; SPIRO COMPOUNDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOSEMICARBAZONES;

EID: 78649319737 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2010.09.051 Document Type: Article

Times cited : (165)

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