메뉴 건너뛰기




Volumn 55, Issue 12, 2010, Pages 3369-3376

Vulnerable sites and changes in mucin in the rat small intestine after non-steroidal anti-inflammatory drugs administration

Author keywords

Jejunum; Loxoprofen sodium; Mesenteric artery; NSAIDs; Sialomucin

Indexed keywords

INDOMETACIN; LOXOPROFEN; SIALOMUCIN;

EID: 78649319295     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1185-6     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 0031438698 scopus 로고    scopus 로고
    • Vascular anatomy defines sites of indomethacin induced jejunal ulceration along the mesenteric margin
    • 1:CAS:528:DyaK1cXks1Whuw%3D%3D 10.1136/gut.41.6.763 9462208
    • A Anthony RE Pounder AP Dhillon AJ Wakefield 1997 Vascular anatomy defines sites of indomethacin induced jejunal ulceration along the mesenteric margin Gut 41 763 770 1:CAS:528:DyaK1cXks1Whuw%3D%3D 10.1136/gut.41.6.763 9462208
    • (1997) Gut , vol.41 , pp. 763-770
    • Anthony, A.1    Pounder, R.E.2    Dhillon, A.P.3    Wakefield, A.J.4
  • 2
    • 84940363565 scopus 로고    scopus 로고
    • Effects of indomethacin on the rat small intestinal mucosa: Immunohistochemical and biochemical studies using antimucin monoclonal antibodies
    • 1:CAS:528:DC%2BD1MXkt1yitbk%3D 10.1007/s00535-009-0007-0 19280111
    • T Iwai T Ichikawa Y Goso, et al. 2009 Effects of indomethacin on the rat small intestinal mucosa: immunohistochemical and biochemical studies using antimucin monoclonal antibodies J. Gastroenterol. 44 277 284 1:CAS:528:DC%2BD1MXkt1yitbk%3D 10.1007/s00535-009-0007-0 19280111
    • (2009) J. Gastroenterol. , vol.44 , pp. 277-284
    • Iwai, T.1    Ichikawa, T.2    Goso, Y.3
  • 3
    • 0036970711 scopus 로고    scopus 로고
    • Pathogenic importance of intestinal hypermotility in NSAIDs-induced small intestinal damage in rats
    • 1:CAS:528:DC%2BD38XnvV2ktLs%3D 10.1159/000064419 12379813
    • K Takeuchi T Miyazawa A Tanaka S Kato T Kunikata 2002 Pathogenic importance of intestinal hypermotility in NSAIDs-induced small intestinal damage in rats Digestion 66 30 41 1:CAS:528:DC%2BD38XnvV2ktLs%3D 10.1159/000064419 12379813
    • (2002) Digestion , vol.66 , pp. 30-41
    • Takeuchi, K.1    Miyazawa, T.2    Tanaka, A.3    Kato, S.4    Kunikata, T.5
  • 4
    • 0037423022 scopus 로고    scopus 로고
    • Role of bacteria and inducible nitric oxide synthase activity in the systemic inflammatory microvascular response provoked by indomethacin in the rat
    • 1:CAS:528:DC%2BD3sXptFKntQ%3D%3D 10.1016/S0014-2999(02)02959-X 12568917
    • SM Evans BJ Whittle 2003 Role of bacteria and inducible nitric oxide synthase activity in the systemic inflammatory microvascular response provoked by indomethacin in the rat Eur. J. Pharmacol. 461 63 71 1:CAS:528: DC%2BD3sXptFKntQ%3D%3D 10.1016/S0014-2999(02)02959-X 12568917
    • (2003) Eur. J. Pharmacol. , vol.461 , pp. 63-71
    • Evans, S.M.1    Whittle, B.J.2
  • 5
    • 1842841170 scopus 로고    scopus 로고
    • Role of unbalanced growth of gram-negative bacteria in ileal ulcer formation in rats treated with a nonsteroidal anti-inflammatory drug
    • 10.2152/jmi.51.43 15000255
    • M Hagiwara K Kataoka H Arimochi T Kuwahara Y Ohnishi 2004 Role of unbalanced growth of gram-negative bacteria in ileal ulcer formation in rats treated with a nonsteroidal anti-inflammatory drug J. Med. Invest. 51 43 51 10.2152/jmi.51.43 15000255
    • (2004) J. Med. Invest. , vol.51 , pp. 43-51
    • Hagiwara, M.1    Kataoka, K.2    Arimochi, H.3    Kuwahara, T.4    Ohnishi, Y.5
  • 6
    • 0031014088 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug enteropathy in rats: Role of permeability, bacteria, and enterohepatic circulation
    • 1:CAS:528:DyaK2sXlvVyjtQ%3D%3D 10.1016/S0016-5085(97)70225-7 8978349
    • BK Reuter NM Davies JL Wallace 1997 Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation Gastroenterology 112 109 117 1:CAS:528:DyaK2sXlvVyjtQ%3D%3D 10.1016/S0016-5085(97)70225-7 8978349
    • (1997) Gastroenterology , vol.112 , pp. 109-117
    • Reuter, B.K.1    Davies, N.M.2    Wallace, J.L.3
  • 7
    • 0019453147 scopus 로고
    • Anti-inflammatory, analgesic and antipyretic activities of sodium 2-(4-(2-oxocycyclopentan-1-ylmethyl) phenyl) propionate dehydrate (CS-600)
    • 1:CAS:528:DyaL38XksF2rsA%3D%3D (Abstract)
    • E Misaka T Yamaguchi Y Iizuka, et al. 1981 Anti-inflammatory, analgesic and antipyretic activities of sodium 2-(4-(2-oxocycyclopentan-1-ylmethyl) phenyl) propionate dehydrate (CS-600) Pharmacometrics 21 753 771 1:CAS:528:DyaL38XksF2rsA%3D%3D (Abstract)
    • (1981) Pharmacometrics , vol.21 , pp. 753-771
    • Misaka, E.1    Yamaguchi, T.2    Iizuka, Y.3
  • 8
    • 0141882971 scopus 로고    scopus 로고
    • Multiple ileal ulcers and an ileal dieulafoy's lesion induced by loxoprofen sodium
    • 10.1046/j.1443-1661.2003.00255.x
    • G Suzuki M Ooishi T Kato, et al. 2003 Multiple ileal ulcers and an ileal dieulafoy's lesion induced by loxoprofen sodium Digestive Endoscopy 15 243 246 10.1046/j.1443-1661.2003.00255.x
    • (2003) Digestive Endoscopy , vol.15 , pp. 243-246
    • Suzuki, G.1    Ooishi, M.2    Kato, T.3
  • 9
    • 10644261336 scopus 로고    scopus 로고
    • Gastroduodenal mucus bicarbonate barrier: Protection against acid and pepsin
    • 1:CAS:528:DC%2BD2MXhtVGjtrY%3D 15591243
    • A Allen G Flemstrom 2005 Gastroduodenal mucus bicarbonate barrier: protection against acid and pepsin Am. J. Physiol. Cell Physiol. 288 C1 C19 1:CAS:528:DC%2BD2MXhtVGjtrY%3D 15591243
    • (2005) Am. J. Physiol. Cell Physiol. , vol.288
    • Allen, A.1    Flemstrom, G.2
  • 10
    • 0018897002 scopus 로고
    • Correlation of quantitative changes of gastric mucosal glycoproteins with aspirin-induced gastric damage in rats
    • 1:CAS:528:DyaL3MXisV2jsA%3D%3D 10.1136/gut.21.6.533 7429315
    • Y Azuumi S Ohara K Ishihara H Okabe K Hotta 1980 Correlation of quantitative changes of gastric mucosal glycoproteins with aspirin-induced gastric damage in rats Gut 21 533 536 1:CAS:528:DyaL3MXisV2jsA%3D%3D 10.1136/gut.21.6.533 7429315
    • (1980) Gut , vol.21 , pp. 533-536
    • Azuumi, Y.1    Ohara, S.2    Ishihara, K.3    Okabe, H.4    Hotta, K.5
  • 11
    • 34948841931 scopus 로고    scopus 로고
    • Effects of a novel histamine H2-receptor antagonist, lafutidine, on the mucus barrier of human gastric mucosa
    • 1:CAS:528:DC%2BD2sXhtlOltb%2FK 10.1111/j.1440-1746.2006.04721.x 17914953
    • T Ichikawa H Ota A Sugiyama F Maruta T Ikezawa K Hotta K Ishihara 2007 Effects of a novel histamine H2-receptor antagonist, lafutidine, on the mucus barrier of human gastric mucosa J Gastroenterol. Hepatol. 22 1800 1805 1:CAS:528:DC%2BD2sXhtlOltb%2FK 10.1111/j.1440-1746.2006.04721.x 17914953
    • (2007) J Gastroenterol. Hepatol. , vol.22 , pp. 1800-1805
    • Ichikawa, T.1    Ota, H.2    Sugiyama, A.3    Maruta, F.4    Ikezawa, T.5    Hotta, K.6    Ishihara, K.7
  • 12
    • 0036086589 scopus 로고    scopus 로고
    • The use of microcomputed tomography to study microvasculature in small rodents
    • 1:CAS:528:DC%2BD38XjslWmtbo%3D 11959666
    • MD Bentley MC Ortiz EL Ritman JC Romero 2002 The use of microcomputed tomography to study microvasculature in small rodents Am. J. Physiol. Regul. Integr. Comp. Physiol. 282 R1267 R1279 1:CAS:528:DC%2BD38XjslWmtbo%3D 11959666
    • (2002) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.282
    • Bentley, M.D.1    Ortiz, M.C.2    Ritman, E.L.3    Romero, J.C.4
  • 13
    • 0026586024 scopus 로고
    • Alternating laminated array of two types of mucin in the human gastric surface mucous layer
    • 1:STN:280:DyaK383ltVehtQ%3D%3D 10.1007/BF01082444 1374372
    • H Ota T Katsuyama 1992 Alternating laminated array of two types of mucin in the human gastric surface mucous layer Histochem. J. 24 86 92 1:STN:280:DyaK383ltVehtQ%3D%3D 10.1007/BF01082444 1374372
    • (1992) Histochem. J. , vol.24 , pp. 86-92
    • Ota, H.1    Katsuyama, T.2
  • 14
    • 0029839147 scopus 로고    scopus 로고
    • Establishment of monoclonal antibodies against carbohydrate moiety of gastric mucins distributed in the different sites and layers of rat gastric mucosa
    • 1:CAS:528:DyaK28XmslCks70%3D 10.1007/BF00702350 8910013
    • K Ishihara M Kurihara Y Goso H Ota T Katsuyama K Hotta 1996 Establishment of monoclonal antibodies against carbohydrate moiety of gastric mucins distributed in the different sites and layers of rat gastric mucosa Glycoconj. J. 13 857 864 1:CAS:528:DyaK28XmslCks70%3D 10.1007/BF00702350 8910013
    • (1996) Glycoconj. J. , vol.13 , pp. 857-864
    • Ishihara, K.1    Kurihara, M.2    Goso, Y.3    Ota, H.4    Katsuyama, T.5    Hotta, K.6
  • 15
    • 0023918211 scopus 로고
    • Favorable feature of loxoprofen sodium, a prodrug, for the irritating effect on gastric mucosa in rats
    • 1:CAS:528:DyaL1cXktVSnsLk%3D (In Japanese with English abstract)
    • T Kojima Y Iizuka 1988 Favorable feature of loxoprofen sodium, a prodrug, for the irritating effect on gastric mucosa in rats Jpn. Pharmacol. Ther. 16 611 619 1:CAS:528:DyaL1cXktVSnsLk%3D (In Japanese with English abstract)
    • (1988) Jpn. Pharmacol. Ther. , vol.16 , pp. 611-619
    • Kojima, T.1    Iizuka, Y.2
  • 16
    • 78649322768 scopus 로고    scopus 로고
    • Absorption, distribution, metabolism and excretion after dermal application of hyrdogel patch containing loxoprofen sodium in rats
    • (In Japanese with English abstract)
    • T Matsuzawa H Saito A Kurihara S Ninomiya K Uohama H Ebine 2006 Absorption, distribution, metabolism and excretion after dermal application of hyrdogel patch containing loxoprofen sodium in rats J. Clini. Ther. Med. 22 187 203 (In Japanese with English abstract)
    • (2006) J. Clini. Ther. Med. , vol.22 , pp. 187-203
    • Matsuzawa, T.1    Saito, H.2    Kurihara, A.3    Ninomiya, S.4    Uohama, K.5    Ebine, H.6
  • 17
    • 34848827170 scopus 로고    scopus 로고
    • Microcirculatory changes in experimental mesenteric longitudinal ulcers of the small intestine in rats
    • 10.1007/s10620-007-9804-6 17393313
    • K Shimizu H Koga M Iida K Haruma 2007 Microcirculatory changes in experimental mesenteric longitudinal ulcers of the small intestine in rats Dig. Dis. Sci. 52 3019 3028 10.1007/s10620-007-9804-6 17393313
    • (2007) Dig. Dis. Sci. , vol.52 , pp. 3019-3028
    • Shimizu, K.1    Koga, H.2    Iida, M.3    Haruma, K.4
  • 18
    • 0031958155 scopus 로고    scopus 로고
    • Focal reduction of villous blood flow in early indomethacin enteropathy: A dynamic vascular study in the rat
    • 1:CAS:528:DyaK1cXitlyrt7s%3D 10.1136/gut.42.3.366 9577343
    • DA Kelly C Piasecki A Anthony AP Dhillon RE Pounder AJ Wakefield 1998 Focal reduction of villous blood flow in early indomethacin enteropathy: a dynamic vascular study in the rat Gut 42 366 373 1:CAS:528:DyaK1cXitlyrt7s%3D 10.1136/gut.42.3.366 9577343
    • (1998) Gut , vol.42 , pp. 366-373
    • Kelly, D.A.1    Piasecki, C.2    Anthony, A.3    Dhillon, A.P.4    Pounder, R.E.5    Wakefield, A.J.6
  • 19
    • 33745963762 scopus 로고    scopus 로고
    • Roles of endogenous prostaglandins and cyclooxygenase isozymes in healing of indomethacin-induced small intestinal lesions in rats
    • 1:CAS:528:DC%2BD28XnslOlsbg%3D 10.1124/jpet.106.103994 16699067
    • R Hatazawa R Ohno M Tanigami A Tanaka K Takeuchi 2006 Roles of endogenous prostaglandins and cyclooxygenase isozymes in healing of indomethacin-induced small intestinal lesions in rats J. Pharmacol. Exp. Ther. 318 691 699 1:CAS:528:DC%2BD28XnslOlsbg%3D 10.1124/jpet.106.103994 16699067
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 691-699
    • Hatazawa, R.1    Ohno, R.2    Tanigami, M.3    Tanaka, A.4    Takeuchi, K.5
  • 20
    • 0019846683 scopus 로고
    • Efficacy of anti-ulcer drugs on the recovery of gastric mucosal glycoproteins with aspirin-induced gastric damage in rat
    • 1:CAS:528:DyaL38XnvFKrtw%3D%3D 7286560
    • Y Azuumi K Ishihara S Ohara H Okabe K Hotta 1981 Efficacy of anti-ulcer drugs on the recovery of gastric mucosal glycoproteins with aspirin-induced gastric damage in rat Gastroenterol. Jpn. 16 331 334 1:CAS:528: DyaL38XnvFKrtw%3D%3D 7286560
    • (1981) Gastroenterol. Jpn. , vol.16 , pp. 331-334
    • Azuumi, Y.1    Ishihara, K.2    Ohara, S.3    Okabe, H.4    Hotta, K.5
  • 21
    • 0026616791 scopus 로고
    • Effects of the M1 muscarinic receptor antagonist pirenzepine on gastric mucus glycoprotein in rats with or without ethanol-induced gastric damage
    • 1:CAS:528:DyaK38XmsVGgsb0%3D 10.3109/00365529209011180 1411283
    • Y Kojima K Ishihara S Ohara K Saigenji K Hotta 1992 Effects of the M1 muscarinic receptor antagonist pirenzepine on gastric mucus glycoprotein in rats with or without ethanol-induced gastric damage Scand. J. Gastroenterol. 27 764 768 1:CAS:528:DyaK38XmsVGgsb0%3D 10.3109/00365529209011180 1411283
    • (1992) Scand. J. Gastroenterol. , vol.27 , pp. 764-768
    • Kojima, Y.1    Ishihara, K.2    Ohara, S.3    Saigenji, K.4    Hotta, K.5
  • 22
    • 24944433414 scopus 로고    scopus 로고
    • Correlation of gastric mucosal damage with sialic acid profile in rats: Effect of hydrochloric acid, pepsin and hypertonic saline
    • 1:CAS:528:DC%2BD2MXhtVCgt7jM 10.1002/cbf.1156 15515124
    • S Yusuf AJ Nok DA Ameh AB Adelaiye EO Balogun 2005 Correlation of gastric mucosal damage with sialic acid profile in rats: effect of hydrochloric acid, pepsin and hypertonic saline Cell Biochem. Funct. 23 339 345 1:CAS:528:DC%2BD2MXhtVCgt7jM 10.1002/cbf.1156 15515124
    • (2005) Cell Biochem. Funct. , vol.23 , pp. 339-345
    • Yusuf, S.1    Nok, A.J.2    Ameh, D.A.3    Adelaiye, A.B.4    Balogun, E.O.5
  • 23
    • 38549158018 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent
    • 1:CAS:528:DC%2BD1cXisVyjsLw%3D 10.1136/gut.2007.125963 17639086
    • T Watanabe K Higuchi A Kobata, et al. 2008 Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependent Gut 57 181 187 1:CAS:528:DC%2BD1cXisVyjsLw%3D 10.1136/gut.2007.125963 17639086
    • (2008) Gut , vol.57 , pp. 181-187
    • Watanabe, T.1    Higuchi, K.2    Kobata, A.3
  • 24
    • 7144253780 scopus 로고    scopus 로고
    • Culture supernatants of Lactobacillus acidophilus and Bifidobacterium adolescentis repress ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug by suppressing unbalanced growth of aerobic bacteria and lipid peroxidation
    • 1:CAS:528:DyaK1cXktFynsL4%3D 9654366
    • T Kinouchi K Kataoka SR Bing, et al. 1998 Culture supernatants of Lactobacillus acidophilus and Bifidobacterium adolescentis repress ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug by suppressing unbalanced growth of aerobic bacteria and lipid peroxidation Microbiol. Immunol. 42 347 355 1:CAS:528:DyaK1cXktFynsL4%3D 9654366
    • (1998) Microbiol. Immunol. , vol.42 , pp. 347-355
    • Kinouchi, T.1    Kataoka, K.2    Bing, S.R.3
  • 25
    • 0031773073 scopus 로고    scopus 로고
    • Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease
    • 1:CAS:528:DyaK1cXnvVCgs7Y%3D 9826389
    • AB Onderdonk JA Richardson RE Hammer JD Taurog 1998 Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease Infect. Immun. 66 6022 6023 1:CAS:528:DyaK1cXnvVCgs7Y%3D 9826389
    • (1998) Infect. Immun. , vol.66 , pp. 6022-6023
    • Onderdonk, A.B.1    Richardson, J.A.2    Hammer, R.E.3    Taurog, J.D.4
  • 26
    • 21044457286 scopus 로고    scopus 로고
    • Protective effect of teprenone against indomethacin-induced small intestinal lesion in rats
    • 1:CAS:528:DC%2BD2MXit1Klurg%3D
    • A Yokota R Ohno Y Takahira A Tanaka K Takeuchi 2005 Protective effect of teprenone against indomethacin-induced small intestinal lesion in rats Jpn. Pharmacol. Ther. 33 51 61 1:CAS:528:DC%2BD2MXit1Klurg%3D
    • (2005) Jpn. Pharmacol. Ther. , vol.33 , pp. 51-61
    • Yokota, A.1    Ohno, R.2    Takahira, Y.3    Tanaka, A.4    Takeuchi, K.5
  • 27
    • 0034768998 scopus 로고    scopus 로고
    • Protective effect of rebamipide on indomethacin-induced intestinal damage in rats
    • 1:CAS:528:DC%2BD3MXpt1Sqt78%3D 10.1046/j.1440-1746.2001.02592.x 11686837 (Abstract)
    • H Mizoguchi Y Ogawa K Kanatsu A Tanaka S Kato K Takeuchi 2001 Protective effect of rebamipide on indomethacin-induced intestinal damage in rats J Gastroenterol. Hepatol. 16 1112 1119 1:CAS:528:DC%2BD3MXpt1Sqt78%3D 10.1046/j.1440-1746.2001.02592.x 11686837 (Abstract)
    • (2001) J Gastroenterol. Hepatol. , vol.16 , pp. 1112-1119
    • Mizoguchi, H.1    Ogawa, Y.2    Kanatsu, K.3    Tanaka, A.4    Kato, S.5    Takeuchi, K.6
  • 28
    • 43249114126 scopus 로고    scopus 로고
    • Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: A prospective, randomized, double-blinded, placebo-controlled, cross-over study
    • 1:CAS:528:DC%2BD1cXlsVOnt74%3D 10.1007/s00535-007-2155-4 18458842
    • Y Niwa M Nakamura N Ohmiya O Maeda T Ando A Itoh Y Hirooka H Goto 2008 Efficacy of rebamipide for diclofenac-induced small-intestinal mucosal injuries in healthy subjects: a prospective, randomized, double-blinded, placebo-controlled, cross-over study J. Gastroenterol. 43 270 276 1:CAS:528:DC%2BD1cXlsVOnt74%3D 10.1007/s00535-007-2155-4 18458842
    • (2008) J. Gastroenterol. , vol.43 , pp. 270-276
    • Niwa, Y.1    Nakamura, M.2    Ohmiya, N.3    Maeda, O.4    Ando, T.5    Itoh, A.6    Hirooka, Y.7    Goto, H.8
  • 29
    • 0035026232 scopus 로고    scopus 로고
    • The adherent gastrointestinal mucus gel layer: Thickness and physical state in vivo
    • 1:CAS:528:DC%2BD3MXjsVahtr0%3D 11292601
    • C Atuma V Strugala A Allen L Holm 2001 The adherent gastrointestinal mucus gel layer: thickness and physical state in vivo Am. J. Physiol. Gastrointest. Liver. Physiol. 280 G922 G929 1:CAS:528:DC%2BD3MXjsVahtr0%3D 11292601
    • (2001) Am. J. Physiol. Gastrointest. Liver. Physiol. , vol.280
    • Atuma, C.1    Strugala, V.2    Allen, A.3    Holm, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.