Induction of antigen-specific CTL and antibody responses in mice by a novel recombinant tandem repeat DNA vaccine targeting at mucin 1 of pancreatic cancer

Journal of Cancer Research and Clinical Oncology

Volumn 136, Issue 12, 2010, Pages 1861-1868

  Wu, Wen Chuan ^a   Jin, Da Yong ^a   Lou, Wen Hui ^a   Wang, Dan Song ^a   Qin, Xin Yu ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

DNA vaccine; Immune response; MUC1; Pancreatic cancer; Tandem repeat

Indexed keywords

DNA VACCINE; MUCIN 1; PLASMID DNA; RECOMBINANT VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; C57BL 6 MOUSE; CANCER IMMUNOTHERAPY; CELL MEDIATED CYTOTOXICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOTOXIC T LYMPHOCYTE; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMORAL IMMUNITY; MOUSE; NONHUMAN; PANCREAS CANCER; PRIORITY JOURNAL; TANDEM REPEAT; TUMOR CELL DESTRUCTION;

ANIMALS; ANTIBODIES; ANTIBODY FORMATION; ANTIGENS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNIZATION; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUCIN-1; PANCREATIC NEOPLASMS; T-LYMPHOCYTES, CYTOTOXIC; TANDEM REPEAT SEQUENCES; TIME FACTORS; VACCINES, DNA;

EID: 78649318717     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-010-0845-4     Document Type: Article

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