Asian dust and titanium dioxide particlesinduced inflammation and oxidative DNA damage in C57BL/6 mice

Inhalation Toxicology

Volumn 22, Issue 13, 2010, Pages 1127-1133

  Hwang, You Jin ^a   Jeung, Ye Sul ^a   Seo, Min Hae ^a   Yoon, Jin Young ^a   Kim, Dae Young ^a   Park, Jeong Woong ^a   Han, Joung Ho ^b   Jeong, Sung Hwan ^a  

^a Gachon University College of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Asian dust; DNA damage; lung inflammation; oxidative stress; TiO2

Indexed keywords

8 HYDROXYGUANINE; ALUMINUM OXIDE; CALCIUM OXIDE; EOSIN; FERRIC OXIDE; HEMATOXYLIN; MAGNESIUM OXIDE; MANGANESE OXIDE; POTASSIUM OXIDE; SILICON DIOXIDE; SODIUM CHLORIDE; SODIUM PEROXIDE; TITANIUM DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASIAN DUST; C57BL 6 MOUSE; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DUST; DUST EXPOSURE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; LUNG PARENCHYMA; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; PERIPHERAL BLOOD MONONUCLEAR CELL; PNEUMONIA; PRIORITY JOURNAL;

AIR POLLUTANTS; ANIMALS; COMET ASSAY; DNA DAMAGE; DUST; FIBROSIS; GUANINE; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; LUNG; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PARTICLE SIZE; PARTICULATE MATTER; TITANIUM;

MUS;

EID: 78649294424     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2010.528805     Document Type: Article

References (30)

1. Azad N, Rojanasakul Y, Vallyathan V. 2008. Infammation and lung cancer: roles of reactive oxygen/nitrogen species. J Toxicol Environ Health B Crit Rev 11:1-15.
2. Bermudez E, Mangum JB, Asgharian B, Wong BA, Reverdy EE, Janszen DB, Hext PM, Warheit DB, Everitt JI. 2002. Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. Toxicol Sci 70:86-97.
3. Bermudez E, Mangum JB, Wong BA, Asgharian B, Hext PM, Warheit DB, Everitt JI. 2004. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafne titanium dioxide particles. Toxicol Sci 77:347-357.
4. Carter JD, Ghio AJ, Samet JM, Devlin RB. 1997. Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent. Toxicol Appl Pharmacol 146:180-188.
5. Cheng MT, Lin YC, Chio CP, Wang CF, Kuo CY. 2005. Characteristics of aerosols collected in central Taiwan during an Asian dust event in spring 2000. Chemosphere 61:1439-1450.
6. Davidson C, Phalen R, Solomon P. 2005. Airborne particulate matter and human health: a review. Aerosol Sience and Technology 39:737-749.
7. Driscoll KE, Deyo LC, Carter JM, Howard BW, Hassenbein DG, Bertram TA. 1997. Efects of particle exposure and particle-elicited infammatory cells on mutation in rat alveolar epithelial cells. Carcinogenesis 18:423-430.
8. Floyd RA. 1990. Te role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11:1447-1450.
9. Gurgueira SA, Lawrence J, Coull B, Murthy GG, González-Flecha B. 2002. Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation. Environ Health Perspect 110:749-755.
10. González-Flecha B. 2004. Oxidant mechanisms in response to ambient air particles. Mol Aspects Med 25:169-182.
11. Hoek G, Brunekreef B, Goldbohm S, Fischer P, van den Brandt PA. 2002. Association between mortality and indicators of trafc-related air pollution in the Netherlands: a cohort study. Lancet 360:1203-1209.
12. Ichinose T, Yoshida S, Sadakane K, Takano H, Yanagisawa R, Inoue K, Nishikawa M, Mori I, Kawazato H, Yasuda A, Shibamoto T. 2008. Efects of asian sand dust, Arizona sand dust, amorphous silica and aluminum oxide on allergic infammation in the murine lung. Inhal Toxicol 20:685-694.
13. Knaapen AM, Borm PJ, Albrecht C, Schins RP. 2004. Inhaled particles and lung cancer. Part A: Mechanisms. Int J Cancer 109:799-809.
14. Long CM, Suh HH, Kobzik L, Catalano PJ, Ning YY, Koutrakis P. 2001. A pilot investigation of the relative toxicity of indoor and outdoor fne particles: in vitro efects of endotoxin and other particulate properties. Environ Health Perspect 109:1019-1026.
15. Mehta M, Chen LC, Gordon T, Rom W, Tang MS. 2008. Particulate matter inhibits DNA repair and enhances mutagenesis. Mutat Res 657:116-121.
16. Møller P, Folkmann JK, Forchhammer L, Bräuner EV, Danielsen PH, Risom L, Loft S. 2008. Air pollution, oxidative damage to DNA, and carcinogenesis. Cancer Lett 266:84-97.
17. Oberdörster G, Oberdörster E, Oberdörster J. 2005. Nanotoxicology: an emerging discipline evolving from studies of ultrafne particles. Environ Health Perspect 113:823-839.
18. Oberdörster G, Stone V, Donaldson K. 2007. Toxicology of nanoparticles: a historical perspective. Nanotoxicology 1:2-25.
19. Olive PL, Frazer G, Banáth JP. 1993. Radiation-induced apoptosis measured in TK6 human B lymphoblast cells using the comet assay. Radiat Res 136:130-136.
20. Park JW, Lim YH, Kyung SY, An CH, Lee SP, Jeong SH, Ju YS. 2005. Efects of ambient particulate matter on peak expiratory fow rates and respiratory symptoms of asthmatics during Asian dust periods in Korea. Respirology 10:470-476.
21. Park EJ, Kim DS, Park K. 2008a. Monitoring of ambient particles and heavy metals in a residential area of Seoul, Korea. Environ Monit Assess 137:441-449.
22. Park KS, Kim YJ, Yoon JY, Kyung SY, An CH, Lee AP, Park JW, Jeong SH. 2008b. Particulate matter 10 from Asian dust storms induces the expression of reactive oxygen species, NF-κB, TGF-β and fbronectin in WI-26 VA4 epithelial cells. Tuberculosis and Respiratory Diseases 65:504-511.
23. Rehn B, Seiler F, Rehn S, Bruch J, Maier M. 2003. Investigations on the infam-matory and genotoxic lung efects of two types of titanium dioxide: untreated and surface treated. Toxicol Appl Pharmacol 189:84-95.
24. Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184-191.
25. Samet JM, Dominici F, Curriero FC, Coursac I, Zeger SL. 2000. Fine particu-late air pollution and mortality in 20 U.S. cities, 1987-1994. N Engl J Med 343:1742-1749.
26. Sánchez-Pérez Y, Chirino YI, Osornio-Vargas AR, Morales-Bárcenas R, Gutiérrez-Ruíz C, Vázquez- López I, García-Cuellar CM. 2009. DNA damage response of A549 cells treated with particulate matter (PM10) of urban air pollutants. Cancer Lett 278:192-200.
27. Tao F, Gonzalez-Flecha B, Kobzik L. 2003. Reactive oxygen species in pulmonary infammation by ambient particulates. Free Radic Biol Med 35:327-340.
28. Utell MJ, Frampton MW. 2000. Acute health efects of ambient air pollution: the ultrafne particle hypothesis. J Aerosol Med 13:355-359.
29. Wang J, Zhou G, Chen C, Yu H, Wang T, Ma Y, Jia G, Gao Y, Li B, Sun J, Li Y, Jiao F, Zhao Y, Chai Z. 2007. Acute toxicity and biodistribution of diferent sized titanium dioxide particles in mice after oral administration. Toxicol Lett 168:176-185.
30. Yang CY, Cheng MH, Chen CC. 2009. Efects of Asian dust storm events on hospital admissions for congestive heart failure in Taipei, Taiwan. J Toxicol Environ Health Part A 72:324-328.