Lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, and clear-cell micronodules in a 39-year-old woman with tuberous sclerosis: A case report

International Journal of Surgical Pathology

Volumn 18, Issue 6, 2010, Pages 522-525

  Chang, Min Hsiang ^a   Yao Peng, Hsu ^a  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

clear cell micronodules; lymphangioleiomyomatosis; multifocal micronodular pneumocyte hyperplasia; perivascular epithelioid cell; tuberous sclerosis complex

Indexed keywords

ADULT; ANGIOMYOLIPOMA; ARTICLE; CASE REPORT; CELL HYPERPLASIA; CELL INFILTRATION; CELL MIGRATION; CELL PROLIFERATION; CYTOPLASM; EPITHELIOID CELL; FEMALE; HISTOGENESIS; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS CELL TYPE 2; LUNG BIOPSY; LYMPHANGIOLEIOMYOMATOSIS; PNEUMOTHORAX; PRIORITY JOURNAL; SPINDLE CELL; THORAX RADIOGRAPHY; TUBEROUS SCLEROSIS;

ADULT; ANGIOMYOLIPOMA; FEMALE; HUMANS; HYPERPLASIA; KIDNEY NEOPLASMS; LYMPHANGIOLEIOMYOMATOSIS; PERIVASCULAR EPITHELIOID CELL NEOPLASMS; PNEUMOCYTES; TUBEROUS SCLEROSIS;

EID: 78649241402     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896910376241     Document Type: Article

References (13)

1. Bourneville DM Sclerose tubereuse des circonvolutions cerebrales: idiotie et epilepsie hemiplegique. Arch Neurol (Paris). 1880 ; 1: 81-91.
2. Crino PB, Nathanson KL, Henske EP The tuberous sclerosis complex. N Engl J Med. 2006 ; 355: 1345-1356.
3. Gomez MR An overview: tuberous sclerosis complex. In: Niimura M, Otsuka F, Hino O, eds. Phacomatosis in Japan. Gann Monograph on Cancer Res. No. 46. Tokyo, Japan: Japan Scientific Societies Press and Karger ; 1999: 17-25.
4. Maruyama H., Ohbayashi C., Hino O., Tsutsumi M., Konishi Y. Pathogenesis of multifocal micronodular pneumocyte hyperplasia a lymaphangioleiomyomatosis in tuberous sclerosis and association with tuberous sclerosis genes TSC1 and TSC2. Pathol Int. 2001 ; 51: 585-594.
5. Flieder DB, Travis WD Clear cell "sugar" tumor of the lung: association with lymphangioleiomyomatosis and multifocal micronodular pneumocyte hyperplasia in a patient with tuberous sclerosis. Am J Surg Pathol. 1997 ; 21: 1242-1247.
6. Chuah KL, Tan PH Multifocal micronodular pneumocyte hyperplasia, lymphangiomyomatosis and clear cell micronodules of the lung in a Chinese female patient with tuberous sclerosis. Pathology. 1998 ; 30: 242-246.
7. Krymskaya VP Smooth muscle-like cell in pulmonary lymphangioleiomyomatosis. Proc Am Thorac Soc. 2008 ; 5: 119-126.
8. Popper HH, Juettner-Smolle FM, Pongratz MG Micronodular hyperplasia of type II pnuemocytes: a new lung lesion associated with tuberous sclerosis. Histopathology. 1991 ; 18: 347-354.
9. Gagné E., Emelin JK, Vinters HV, Colby TV Micronodular pneumocyte hyperplasia. Am J Surg Pathol. 1998 ; 22: 465-472.
10. Maruyama H., Seyama K., Sobajima J., et al. Multifocal micronodular pneumocyte hyperplasia and lymphangioleiomyomatosis in tuberous sclerosis with a TSC2 gene. Mod Pathol. 2001 ; 14: 609-614.
11. Liebow AA, Castleman B. Benign "clear cell tumors" of the lung. Am J Pathol. 1963 ; 43: 13-14.
12. Bonetti F., Pea M. Clear cell ("sugar") tumor of the lung is a lesion strictly related to angiomyolipoma: the concept of a family of lesions characterized by the presence of the perivascular epithelioid cells (PEC). Pathology. 1994 ; 26: 230-236.
13. Liang SX, Pearl M., Liu J., Hwang S., Tornos C. " Malignant" uterine perivascular epithelioid cell tumor, pelvic lymph node lymphangioleiomyomatosis, and gynecological pecomatosis in a patient with tuberous sclerosis: a case report and review of the literature. Int J Gynecol Pathol. 2008 ; 27: 86-90.