Multifocal micronodular pneumocyte hyperplasia and lymphangioleiomyomatosis in tuberous sclerosis with a TSC2 gene

Modern Pathology

Volumn 14, Issue 6, 2001, Pages 609-614

  Maruyama, Hiroshi ^a   Seyama, Kuniaki ^b   Sobajima, Junko ^a   Kitamura, Kazumichi ^a   Sobajima, Tooru ^a   Fukuda, Tomokazu ^c   Hamada, Kaoru ^d   Tsutsumi, Masahiro ^d   Hino, Okio ^c   Konishi, Yoichi ^d  

^a HOSHIGAOKA KOSEINENKIN HOSPITAL   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c CANCER INSTITUTE   (Japan)

^d NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Loss of heterozygosity (LOH); Lymphangioleiomyomatosis (LAM); Multifocal micronodular pneumocyte hyperplasia (MMPH); PCR SSCP; TSC2 gene; Tuberin; Tuberous sclerosis (TSC)

Indexed keywords

GENE PRODUCT; KERATIN; LUNG SURFACTANT; MONOCLONAL ANTIBODY; PARAFFIN; TUBERIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CASE REPORT; CELL HYPERPLASIA; CELL PROLIFERATION; CHROMOSOME MICRODISSECTION; EXON; FEMALE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL TYPE 2; LYMPHANGIOLEIOMYOMATOSIS; OPEN LUNG BIOPSY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; SPINDLE CELL; SPONTANEOUS PNEUMOTHORAX; TUBEROUS SCLEROSIS;

ADULT; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; HUMANS; HYPERPLASIA; LOSS OF HETEROZYGOSITY; LUNG; LUNG NEOPLASMS; LYMPHANGIOLEIOMYOMATOSIS; MIDDLE AGED; MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; REPRESSOR PROTEINS; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 17844362192     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880359     Document Type: Article

References (13)

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2. An overview: Tuberous sclerosis complex
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5. HMB-45 and tuberin in hamartomas associated with tuberous sclerosis
6. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
7. Multifocal micronodular pneumocyte hyperplasia: A distinctive pulmonary manifestation of tuberous sclerosis
8. The lung in tuberous sclerosis
9. Micronodular pneumocyte hyperplasia
10. Pulmonary angiomyolipoma and multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis
11. Multifocal micronodular pneumocyte hyperplasia in a postmenopausal woman with tuberous sclerosis
12. Analysis of all exons of TSC1 and TSC2 genes for germline mutations in Japanese patients with tuberous sclerosis: Report of 10 mutations
13. Mutations in the tuberous sclerosis complex gene TSC2 are a cause of sporadic pulmonary lymphangioleiomyomatosis