The relationship between cardiac output and dynamic cerebral autoregulation in humans

Journal of Applied Physiology

Volumn 109, Issue 5, 2010, Pages 1424-1431

  Deegan, B M ^a,b,c   Devine, E R ^c   Geraghty, M C ^c,d   Jones, E ^a,b   OLaighin G ^a,b   Serrador, J M ^a,b,c,e  

^a School of Engineering and Informatics   (Ireland)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d UNIVERSITY COLLEGE DUBLIN   (Ireland)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cerebral blood flow; Echocardiography; Transcranial Doppler

Indexed keywords

ADULT; ANTERIOR CEREBRAL ARTERY; ARTICLE; BLOOD FLOW; BLOOD PRESSURE; BRAIN CIRCULATION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER ECHOGRAPHY; ECHOCARDIOGRAPHY; ECHOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HEART OUTPUT; HEART RATE; HOMEOSTASIS; HUMAN; HYPOTENSION; MALE; MIDDLE CEREBRAL ARTERY; PATHOPHYSIOLOGY; PHOTOELECTRIC PLETHYSMOGRAPHY; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SUPINE POSITION; THIGH; TIME; VASCULAR RESISTANCE; VASCULARIZATION;

ADULT; ANTERIOR CEREBRAL ARTERY; BLOOD PRESSURE; CARDIAC OUTPUT; CEREBROVASCULAR CIRCULATION; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; HOMEOSTASIS; HUMANS; HYPOTENSION; MALE; MIDDLE CEREBRAL ARTERY; PHOTOPLETHYSMOGRAPHY; REGIONAL BLOOD FLOW; SEX FACTORS; SUPINE POSITION; THIGH; TIME FACTORS; ULTRASONOGRAPHY, DOPPLER, TRANSCRANIAL; VASCULAR RESISTANCE; YOUNG ADULT;

EID: 78549293247     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01262.2009     Document Type: Article

References (36)

1. Aaslid R, Lindegaard KF, Sorteberg W, Nornes H. Cerebral autoregulation dynamics in humans. Stroke 20: 45-52, 1989.
2. Aaslid R, Markwalder TM, Nornes H. Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries. J Neurosurg 57: 769-774, 1982.
3. Bouma GJ, Muizelaar JP. Relationship between cardiac output and cerebral blood flow in patients with intact and with impaired autoregulation. J Neurosurg 73: 368-374, 1990.
4. Brown CM, Dutsch M, Hecht MJ, Neundorfer B, Hilz MJ. Assessment of cerebrovascular and cardiovascular responses to lower body negative pressure as a test of cerebral autoregulation. J Neurol Sci 208: 71-78, 2003.
5. Christie J, Sheldahl LM, Tristani FE, Sagar KB, Ptacin MJ, Wann S. Determination of stroke volume and cardiac output during exercise: comparison of two-dimensional and Doppler echocardiography, Fick oximetry, and thermodilution. Circulation 76: 539-547, 1987.
6. Eicke BM, von Schlichting J, Mohr-Ahaly S, Schlosser A, von Bardeleben RS, Krummenauer F, Hopf HC. Lack of association between carotid artery volume blood flow and cardiac output. J Ultrasound Med 20: 1293-1298, 2001.
7. Gordon EP, Schnittger I, Fitzgerald PJ, Williams P, Popp RL. Reproducibility of left ventricular volumes by two-dimensional echocardiography. J Am Coll Cardiol 2: 506-513, 1983.
8. Guo H, Tierney N, Schaller F, Raven PB, Smith SA, Shi X. Cerebral autoregulation is preserved during orthostatic stress superimposed with systemic hypotension. J Appl Physiol 100: 1785-1792, 2006.
9. Gur RE, Gur RC. Gender differences in regional cerebral blood flow. Schizophr Bull 16: 247-254, 1990.
10. Ide K, Boushel R, Sorensen HM, Fernandes A, Cai Y, Pott F, Secher NH. Middle cerebral artery blood velocity during exercise with beta-1 adrenergic and unilateral stellate ganglion blockade in humans. Acta Physiol Scand 170: 33-38, 2000.
11. Ide K, Gullov AL, Pott F, Van Lieshout JJ, Koefoed BG, Petersen P, Secher NH. Middle cerebral artery blood velocity during exercise in patients with atrial fibrillation. Clin Physiol 19: 284-289, 1999.
12. Ide K, Pott F, van Lieshout JJ, Secher NH. Middle cerebral artery blood velocity depends on cardiac output during exercise with a large muscle mass. Acta Physiol Scand 162: 13-20, 1998.
13. Immink RV, Truijen J, Secher NH, Van Lieshout JJ. Transient influence of end-tidal carbon dioxide tension on the postural restraint in cerebral perfusion. J Appl Physiol 107: 816-823, 2009.
14. Joseph M, Ziadi S, Nates J, Dannenbaum M, Malkoff M. Increases in cardiac output can reverse flow deficits from vasospasm independent of blood pressure: a study using xenon computed tomographic measurement of cerebral blood flow. Neurosurgery 53: 1044-1051, 2003.
15. Larsen FS, Strauss G, Knudsen GM, Herzog TM, Hansen BA, Secher NH. Cerebral perfusion, cardiac output, and arterial pressure in patients with fulminant hepatic failure. Crit Care Med 28: 996-1000, 2000.
16. Levine BD, Giller CA, Lane LD, Buckey JC, Blomqvist CG. Cerebral versus systemic hemodynamics during graded orthostatic stress in humans. Circulation 90: 298-306, 1994.
17. Mosteller RD. Simplified calculation of body-surface area. N Engl J Med 317: 1098, 1987.
18. Nosir YFM, Vletter WB, Boersma E, Frowijn R, Ten Cate FJ, Fioretti PM, Roelandt J. The apical long-axis rather than the two-chamber view should be used in combination with the four-chamber view for accurate assessment of left ventricular volumes and function. Eur Heart J 18: 1175-1185, 1997.
19. Ogawa Y, Iwasaki K, Aoki K, Shibata S, Kato J, Ogawa S. Central hypervolemia with hemodilution impairs dynamic cerebral autoregulation. Anesth Analg 105: 1389-1396, 2007.
20. Ogoh S, Brothers RM, Barnes Q, Eubank WL, Hawkins MN, Purkayastha S, Raven PB. The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exercise. J Physiol 569: 697-704, 2005.
21. Ogoh S, Dalsgaard MK, Secher NH, Raven PB. Dynamic blood pressure control and middle cerebral artery mean blood velocity variability at rest and during exercise in humans. Acta Physiol (Oxf) 191: 3-14, 2007. (Pubitemid 47221191)
22. Ogoh S, Tzeng YC, Lucas SJ, Galvin SD, Ainslie PN. Influence of baroreflex-mediated tachycardia on the regulation of dynamic cerebral perfusion during acute hypotension in humans. J Physiol 588: 365-371, 2010.
23. Paulson OB, Strandgaard S, Edvinsson L. Cerebral autoregulation. Cerebrovasc Brain Metab Rev 2: 161-192, 1990.
24. Serrador JM, Sorond FA, Vyas M, Gagnon M, Iloputaife ID, Lipsitz LA. Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains. J Appl Physiol 98: 151-159, 2005.
25. Smith SM, Padayachee S, Modaresi KB, Smithies MN, Bihari DJ. Cerebral blood flow is proportional to cardiac index in patients with septic shock. J Crit Care 13: 104-109, 1998.
26. Tiecks FP, Lam AM, Aaslid R, Newell DW. Comparison of static and dynamic cerebral autoregulation measurements. Stroke 26: 1014-1019, 1995.
27. Tontisirin N, Muangman SL, Suz P, Pihoker C, Fisk D, Moore A, Lam AM, Vavilala MS. Early childhood gender differences in anterior and posterior cerebral blood flow velocity and autoregulation. Pediatrics 119: e610-e615, 2007.
28. Tranmer BI, Keller TS, Kindt GW, Archer D. Loss of cerebral regulation during cardiac output variations in focal cerebral ischemia. J Neurosurg 77: 253-259, 1992.
29. Tzeng YC, Lucas SJ, Atkinson G, Willie CK, Ainslie PN. Fundamental relationships between arterial baroreflex sensitivity and dynamic cerebral autoregulation in humans. J Appl Physiol 108: 1162-1168, 2010.
30. van Lieshout JJ, Pott F, Madsen PL, van Goudoever J, Secher NH. Muscle tensing during standing: effects on cerebral tissue oxygenation and cerebral artery blood velocity. Stroke 32: 1546-1551, 2001.
31. Van Lieshout JJ, Wieling W, Karemaker JM, Secher NH. Syncope, cerebral perfusion, oxygenation. J Appl Physiol 94: 833-848, 2003.
32. Vavilala MS, Kincaid MS, Muangman SL, Suz P, Rozet I, Lam AM. Gender differences in cerebral blood flow velocity and autoregulation between the anterior and posterior circulations in healthy children. Pediatr Res 58: 574-578, 2005.
33. Vinall PE, Simeone FA. Cerebral autoregulation: an in vitro study. Stroke 12: 640-642, 1981.
34. Wang X, Krishnamurthy S, Evans J, Bhakta D, Justice L, Bruce E, Patwardhan A. Transfer function analysis of gender-related differences in cerebral autoregulation. Biomed Sci Instrum 41: 48-53, 2005.
35. Wilson TE, Cui J, Zhang R, Witkowski S, Crandall CG. Skin cooling maintains cerebral blood flow velocity and orthostatic tolerance during tilting in heated humans. J Appl Physiol 93: 85-91, 2002.
36. Zhang R, Levine BD. Autonomic ganglionic blockade does not prevent reduction in cerebral blood flow velocity during orthostasis in humans. Stroke 38: 1238-1244, 2007.