Influence of baroreflex-mediated tachycardia on the regulation of dynamic cerebral perfusion during acute hypotension in humans

Journal of Physiology

Volumn 588, Issue 2, 2010, Pages 365-371

  Ogoh, Shigehiko ^a   Tzeng, Yu Chieh ^b   Lucas, Samuel J E ^b   Galvin, Sean D ^b   Ainslie, Philip N ^c  

^a TOYO UNIVERSITY   (Japan)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING; ADULT; ARTICLE; BRAIN BLOOD FLOW; BRAIN PERFUSION; CONTROLLED STUDY; FEMALE; HEART OUTPUT; HEART RATE; HUMAN; HUMAN EXPERIMENT; HYPOTENSION; MALE; MEAN ARTERIAL PRESSURE; MIDDLE CEREBRAL ARTERY; NORMAL HUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYMPATHETIC BLOCKING; TACHYCARDIA; AUTOREGULATION; BLOOD FLOW VELOCITY; CHOLINERGIC RECEPTOR BLOCKING; HEART STROKE VOLUME;

ADULT; ANALYSIS OF VARIANCE; ANTIHYPERTENSIVE AGENTS; BAROREFLEX; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CARDIAC OUTPUT; CEREBROVASCULAR CIRCULATION; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HEART RATE; HOMEOSTASIS; HUMANS; HYPOTENSION; MALE; MIDDLE CEREBRAL ARTERY; NITROPRUSSIDE; PHENYLEPHRINE; SYMPATHOMIMETICS; TACHYCARDIA;

BETA 1 ADRENERGIC RECEPTOR; GLYCOPYRRONIUM BROMIDE; METOPROLOL TARTRATE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE;

EID: 74549166037     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2009.180844     Document Type: Article

References (27)

1. Aaslid R, Lindegaard KF, Sorteberg W, Nornes H. Cerebral autoregulation dynamics in humans. Stroke 1989, 20:45-52.
2. Carey BJ, Eames PJ, Blake MJ, Panerai RB, Potter JF. Dynamic cerebral autoregulation is unaffected by aging. Stroke 2000, 31:2895-2900.
3. Fadel PJ, Ogoh S, Keller DM, Raven PB. Recent insights into carotid baroreflex function in humans using the variable pressure neck chamber. Exp Physiol 2003a, 88:671-680.
4. Fadel PJ, Stromstad M, Hansen J, Sander M, Horn K, Ogoh S, Smith ML, Secher NH, Raven PB. Arterial baroreflex control of sympathetic nerve activity during acute hypotension: effect of fitness. Am J Physiol Heart Circ Physiol 2001, 280:H2524-H2532.
5. Fadel PJ, Stromstad M, Wray DW, Smith SA, Raven PB, Secher NH. New insights into differential baroreflex control of heart rate in humans. Am J Physiol Heart Circ Physiol 2003b, 284:H735-H743.
6. Giller CA, Bowman G, Dyer H, Mootz L, Krippner W. Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy. Neurosurgery 1993, 32:737-741. discussion 741-732
7. Head GA. Cardiac baroreflexes and hypertension. Clin Exp Pharmacol Physiol 1994, 21:791-802.
8. Immink RV, Van Den Born BJ, van Montfrans GA, Koopmans RP, Karemaker JM, van Lieshout JJ. Impaired cerebral autoregulation in patients with malignant hypertension. Circulation 2004, 110:2241-2245.
9. La Rovere MT, Bersano C, Gnemmi M, Specchia G, Schwartz PJ. Exercise-induced increase in baroreflex sensitivity predicts improved prognosis after myocardial infarction. Circulation 2002, 106:945-949.
10. La Rovere MT, Bigger JT, Marcus FI, Mortara A, Schwartz PJ. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (autonomic tone and reflexes after myocardial infarction) investigators. Lancet 1998, 351:478-484.
11. Lassen NA. Cerebral blood flow and oxygen consumption in man. Physiol Rev 1959, 39:183-238.
12. Liu AJ, Ma XJ, Shen FM, Liu JG, Chen H, Su DF. Arterial baroreflex: a novel target for preventing stroke in rat hypertension. Stroke 2007, 38:1916-1923.
13. Mussalo H, Vanninen E, Ikaheimo R, Laitinen T, Laakso M, Lansimies E, Hartikainen J. Baroreflex sensitivity in essential and secondary hypertension. Clin Auton Res 2002, 12:465-471.
14. Ogoh S, Brothers RM, Barnes Q, Eubank WL, Hawkins MN, Purkayastha S, O-Yurvati A, Raven PB. The effect of changes in cardiac output on middle cerebral artery mean blood velocity at rest and during exercise. J Physiol 2005a, 569:697-704.
15. Ogoh S, Brothers RM, Eubank WL, Raven PB. Autonomic neural control of the cerebral vasculature: acute hypotension. Stroke 2008, 39:1979-1987.
16. Ogoh S, Dalsgaard MK, Secher NH, Raven PB. Dynamic blood pressure control and middle cerebral artery mean blood velocity variability at rest and during exercise in humans. Acta Physiol (Oxf) 2007, 191:3-14.
17. Ogoh S, Dalsgaard MK, Yoshiga CC, Dawson EA, Keller DM, Raven PB, Secher NH. Dynamic cerebral autoregulation during exhaustive exercise in humans. Am J Physiol Heart Circ Physiol 2005b, 288:H1461-H1467.
18. Ogoh S, Fadel PJ, Nissen P, Jans O, Selmer C, Secher NH, Raven PB. Baroreflex-mediated changes in cardiac output and vascular conductance in response to alterations in carotid sinus pressure during exercise in humans. J Physiol 2003, 550:317-324.
19. Ogoh S, Fadel PJ, Zhang R, Selmer C, Jans O, Secher NH, Raven PB. Middle cerebral artery flow velocity and pulse pressure during dynamic exercise in humans. Am J Physiol Heart Circ Physiol 2005c, 288:H1526-H1531.
20. Paulson OB, Strandgaard S, Edvinsson L. Cerebral autoregulation. Cerebrovasc Brain Metab Rev 1990, 2:161-192.
21. Potts JT, Raven PB. Effect of dynamic exercise on human carotid-cardiac baroreflex latency. Am J Physiol Heart Circ Physiol 1995, 268:H1208-H1214.
22. Secher NH, Seifert T, Van Lieshout JJ. Cerebral blood flow and metabolism during exercise: implications for fatigue. J Appl Physiol 2008, 104:306-314.
23. Serrador JM, Picot PA, Rutt BK, Shoemaker JK, Bondar RL. MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis. Stroke 2000, 31:1672-1678.
24. Serrador JM, Sorond FA, Vyas M, Gagnon M, Iloputaife ID, Lipsitz LA. Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains. J Appl Physiol 2005, 98:151-159.
25. Tiecks FP, Lam AM, Aaslid R, Newell DW. Comparison of static and dynamic cerebral autoregulation measurements. Stroke 1995, 26:1014-1019.
26. Zhang R, Zuckerman JH, Iwasaki K, Wilson TE, Crandall CG, Levine BD. Autonomic neural control of dynamic cerebral autoregulation in humans. Circulation 2002, 106:1814-1820.
27. Zhang R, Zuckerman JH, Levine BD. Deterioration of cerebral autoregulation during orthostatic stress: insights from the frequency domain. J Appl Physiol 1998, 85:1113-1122.