Cytotoxicity and antibacterial studies of iridoids and phenolic compounds isolated from the latex of himatanthus sucuuba

African Journal of Biotechnology

Volumn 9, Issue 43, 2010, Pages 7357-7360

  Silva, Jefferson Rocha A ^a   Rezende, Claudia M ^b   Pinto, Angelo C ^b   Amaral, Ana Claudia F ^c  

^a FEDERAL UNIVERSITY OF AMAZONAS   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Antibacterial; Cytotoxicity; Himatanthus sucuuba; Iridoids; Phenolics

Indexed keywords

GALLIC ACID; IRIDOID; ISOPLUMERICIN; LATEX; MYRICETRIN; PHENOL DERIVATIVE; PLUMERICIN; QUERCITRIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOCYNACEAE; ARTICLE; BIOASSAY; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ESCHERICHIA COLI; FRACTIONATION; HIMATANTHUS SUCUUBA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTEUS MIRABILIS; SALMONELLA TYPHIMURIUM; SHIGELLA SONNEI; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS HAEMOLYTICUS;

HIMATANTHUS SUCUUBA; PICEA;

EID: 78549288466     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Abdel-Kader MS, Wisse J, Evans R, Werff H, Kingston DGI (1997). Bioactive iridoids and a new lignan from Allamanda cathartica and Himatanthus falax from the Suriname rainforest. J. Nat. Prod. 60: 1294-1297.
2. Amaral ACF, Ferreira JLP, Pinheiro MLB, Silva JRA (2007). Monograph of Himatanthus sucuuba, a plant of Amazonian folk medicine Phcog. Rev. 1: 77-85.
3. Barreto AS, Silva JRA, Amaral ACF, Schripsema J, Rezende CM, Pinto AC (2007). Ácido 15-desmetilisoplumierídeo, um novo iridóide isolado das cascas de Plumeria rubra e do látex de Himatanthus sucuuba. Quim. Nova, 30: 1133-1135.
4. Bourdy G, DeWalt SJ, Michel LRC, Roca A, Deharo E, Munõz V, Balderrama L, Quenevo C, Gimenez A (2000). Medicinal plants uses of the Tacana, na Amazonian Bolivian ethnic group. J. Ethnopharmacol. 70: 87-109.
5. Castillo D, Arevalo J, Herrera F, Ruiz C, Rojas R, Rengifo E, Vaisberg A, Lock O, Lemesre JL, Gornitzka H, Sauvain M (2007). Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae). J. Ethnopharmacol. 112: 410-414.
6. Chanwitheesuk A, Teerawutgulrag A, Kilburn JD, Rakariyatham N (2007). Antimicrobial gallic acid from Caesalpinia mimosoides Lamk. Food Chem. 100: 1044-1048.
7. Gunatilaka AAL, Kingston DGI, Johnson RK (1994). Mechanism-based isolation and structures of some anticancer active natural products. Pure Appl. Chem. 66: 2219-2222.
8. Gunatilaka AAL, Samaranayake G, Kingston DGI, Hofmann G, Johnson RK. (1992). Bioactive ergost-5-ene-3b, 7a-diol derivatives from Pseudobersama mossambicensis. J. Nat. Prod. 55: 1648-1654.
9. Mabry TJ, Markham KR, Thomas MB (1970). The Systematic Identification of Flavonoids. Springer Verlag, New York.
10. Machado TB, Pinto AV, Pinto MCFR, Leal ICR, Silva MG, Amaral ACF, Kuster RM, Netto-dos Santos KR (2003). In vitro activity of Brazilian medicinal plants, naturally occurring naphthoquinones and their analogues, against methicillin-resistant Staphylococcus aureus. Int. J. Antimicrob. Agents, 21: 279-284.
11. Miranda ALP, Silva JRA, Rezende CM, Pinto AC, Pinheiro MLB, Cordeiro MC, Tamborini E, Parrini JS (2000). Anti-inflammatory and analgesic activities of the latex containing triterpenes from Himatanthus sucuuba. Planta Med. 66: 284-286.
12. National Council for Clinical Laboratory Standards (1993). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard M7-A3, third ed. Villanova, PA, USA: NCCLS.
13. Perdue GP, Blomster RN (1978). South American Plants III: Isolation of fulvoplumierin from Himatanthus sucuuba (M. Arg.) Woodson (Apocynaceae). J. Pharm. Sci. 67: 1322-1323.
14. Schultes RE (1979). De plantis toxicariie e mundo novo tropicale commentationes. XIX. Biodynamic apocynaceous plants of the northwest Amazon. J. Ethnopharmacol. 1: 165-192.
15. Silva JRA, Rezende CM, Pinto AC, Pinheiro MLB, Cordeiro MC, Tamborini E, Young CM, Bolzani VS (1998). Ésteres triterpênicos de Himatanthus sucuuba (Spruce) Woodson. Quim. Nova, 21: 702-704.
16. Souza VC, Lorenzi H. (2005). Botânica Sistemática: Guia Ilustrado para a identifcação das famílias de Angiospermas da Flora Brasileira. Nova Odessa, Sp. Instituto Plantarum.
17. Trost BM, Mao MKT, Balkovec JM, Buhlmayer P (1986). A total synthesis of plumericin, allamcin and allamandin. 1. Basic strategy. J. Am. Chem. Soc. 108: 4965-4973.
18. Van Den Berg ME (1982). Plantas medicinais na Amazônia: contribuição ao seu conhecimento sistemático, CNPq/PRU/MPEG, Belém, Brasil.
19. Villegas LF, Fernandez ID, Maldonado H, Torres R, Zavaleta A, Vaisberg AJ, Hammond GB (1997). Evaluation of the wound-healing activity of selected traditional medicinal plants from Peru. J. Ethnopharmacol. 55: 193-200.
20. Wood CA, Lee K, Vaisberg AJ, Kingston DGI, Neto CC, Hammond GB (2001). A bioactive spirolactone iridoid and triterpenoids from Himatanthus sucuuba. Chem. Pharm. Bull. 49: 1477-1478.