Non-specificity of chloride channel blockers in rat cerebral arteries: Block of the L-type calcium channel

Journal of Physiology

Volumn 507, Issue 2, 1998, Pages 433-439

  Doughty, Joanne M ^a   Miller, Alastair L ^a   Langton, Philip D ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; 9 ANTHRACENE CHLORIDE; BARIUM ION; CALCIUM CHANNEL; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; FLUFENAMIC ACID; GLIBENCLAMIDE; INDANYLOXYACETIC ACID; POTASSIUM ION; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; CALCIUM CHANNEL L TYPE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTERY CONSTRICTION; ARTICLE; BRAIN ARTERY; CONTROLLED STUDY; DRUG EFFECT; DRUG SPECIFICITY; ION CURRENT; MUSCLE ISOMETRIC CONTRACTION; MYOGRAPHY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; ANIMAL EXPERIMENT; CHLORIDE CONDUCTANCE; HALPERN PRESSURE MYOGRAPHY; IC50; ISOMETRICS; MULVANY WIRE MYOGRAPHY; RABBIT; TEMPERATURE DEPENDENCE; WHOLE CELL PATCH CLAMP;

ANIMALS; BARIUM; CALCIUM CHANNEL BLOCKERS; CEREBRAL ARTERIES; CHLORIDE CHANNELS; ELECTROPHYSIOLOGY; ISOMETRIC CONTRACTION; MEMBRANE POTENTIALS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOGRAPHY; NITROBENZOATES; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR;

EID: 0032032394     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1998.433bt.x     Document Type: Article

References (20)

1. AICKIN, C. C. (1990). Chloride transport across the sarcolemma of vertebrate smooth and skeletal muscle. In Chloride Channels and Carriers in Nerve, Muscle and Glial Cells, ed. ALVAREZ-LEEFMANS, F. J. & RUSSEL, J. M., pp. 209-249. Plenum Press, New York.
2. BAYLISS, W. M. (1902). On the local reactions of the arterial wall to changes of internal pressure. Journal of Physiology 28, 220-231.
3. CHIPPERFIELD, A. R., DAVIS, J. P. L. & HARPER, A. A. (1997). Activation of two inward chloride pumps in rat arterial smooth muscle by noradrenaline in vitro. Journal of Physiology 501.P, 116P.
4. CRIDDLE, D. N., SOARES DE MOURA, R., GREENWOOD, I. A. & LARGE, W. A. (1996). Effect of niflumic acid on noradrenaline-induced contractions of the rat aorta. British Journal of Pharmacology 118, 1065-1071.
5. HALPERN, W., OSOL, G. & COY, G. S. (1984). Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system. Annals of Biomedical Engineering 12, 463-479.
6. HARDER, D. R. (1984). Pressure-dependent membrane depolarization in cat middle cerebral artery. Circulation Research 55, 197-202.
7. HARDER, D. R., GILBERT, R. & LOMBARD, J. H. (1987). Vascular muscle-cell depolarization and activation in renal arteries on elevation of transmural pressure. American Journal of Physiology 253, F778-781.
8. HOGG, R. C., WANG, Q. & LARGE, W. A. (1994). Action of niflumic acid on evoked and spontaneous calcium-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein. British Journal of Pharmacology 112, 977-984.
9. IYADOMI, I., HIRAHARA, K. & EHARA, T. (1995). α-Adrenergic inhibition of the β-adrenoceptor-dependent chloride current in guinea-pig ventricular myocytes. Journal of Physiology 489, 95-104.
10. KIRKUP, A. J., EDWARDS, G. & WESTON, A. H. (1996). Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein. British Journal of Pharmacology 117, 175-183.
11. 2+] in intact cerebral arteries by membrane potential and the sarcoplasmic reticulum. Biophysical Journal 72, TU273.
12. LANGTON, P. D. (1993). A versatile superfusion system suitable for whole-cell and exercised patch clamp experiments. Journal of Physiology 467, 244P.
13. - conductance in smooth muscle. American Journal of Physiology 271, C435-454.
14. MULVANY, M. J. & HALPERN, W. (1977). Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circulation Research 41, 19-26.
15. NELSON, M. T., CONWAY, M. A., KNOT, H. J. & BRAYDEN, J. E. (1997). Chloride channel blockers inhibit myogenic tone in rat cerebral arteries. Journal of Physiology 502, 259-264.
16. NELSON, M. T., PATLAK, J. B., WORLEY, J. F. & STANDEN, N. B. (1990). Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone. American Journal of Physiology 259, C3-18.
17. 2+ channel activation and membrane depolarization mediated by CF channels in response to noradrenaline in vascular myocytes. British Journal of Pharmacology 104, 1000-1006.
18. SALVAIL, D., ALIOUA, A. & ROUSSEAU, E. (1996). Functional identification of a sarcolemmal chloride channel from bovine tracheal smooth muscle. American Journal of Physiology 271, C1716-1724.
19. VANRENTERGHEM, C. & LAZDUNSKI, M. (1993). Endothelin and vasopressin activate low-conductance chloride channels in aortic smooth-muscle cells. Pflügers Archiv 425, 156-163.
20. 2+-activated CF channels in mammalian cardiac myocytes. Circulation Research 81, 101-109.