-
1
-
-
0031686054
-
Nuclear lamins: Their structure, assembly and interactions
-
Stuurman N, Heins S, Aebi U. Nuclear lamins: their structure, assembly and interactions. J Struct Biol 1998; 122:42-66.
-
(1998)
J Struct Biol
, vol.122
, pp. 42-66
-
-
Stuurman, N.1
Heins, S.2
Aebi, U.3
-
2
-
-
34250880140
-
Intermediate filaments: From cell architecture to nanomechanics
-
Herrmann H, Bär H, Kreplak L, Strelkov SV, Aebi U. Intermediate filaments: from cell architecture to nanomechanics. Nat Rev Cell Mol Biol 2007; 8:562-73.
-
(2007)
Nat Rev Cell Mol Biol
, vol.8
, pp. 562-573
-
-
Herrmann, H.1
Bär, H.2
Kreplak, L.3
Strelkov, S.V.4
Aebi, U.5
-
3
-
-
0036500259
-
Nuclear lamins: Building blocks of nuclear architecture
-
Goldman RD, Gruenbaum Y, Moir RD, Shumaker DK, Spann TP. Nuclear lamins: building blocks of nuclear architecture. Genes Dev 2002; 16:533-47.
-
(2002)
Genes Dev
, vol.16
, pp. 533-547
-
-
Goldman, R.D.1
Gruenbaum, Y.2
Moir, R.D.3
Shumaker, D.K.4
Spann, T.P.5
-
4
-
-
11244320353
-
The nuclear lamina comes of age
-
Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL. The nuclear lamina comes of age. Nat Rev Mol Cell Biol 2005; 6:21-31.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 21-31
-
-
Gruenbaum, Y.1
Margalit, A.2
Goldman, R.D.3
Shumaker, D.K.4
Wilson, K.L.5
-
7
-
-
33846484332
-
Human progeroid syndromes, aging and cancer: New genetic and epigenetic insights into old questions
-
Ramírez CL, Cadiñanos J, Varela I, Freije JM, López- Otín C. Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions. Cell Mol Life Sci 2007; 64:155-70.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 155-170
-
-
Ramírez, C.L.1
Cadiñanos, J.2
Varela, I.3
Freije, J.M.4
López-Otín, C.5
-
8
-
-
41649097238
-
Nuclear lamins: Major factors in the structural organization and function of the nucleus and chromatin
-
Dechat T, Pfleghaar K, Sengupta K, Shimi T, Shumaker DK, Solimando L, Goldman RD. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev 2008; 22:832-53.
-
(2008)
Genes Dev
, vol.22
, pp. 832-853
-
-
Dechat, T.1
Pfleghaar, K.2
Sengupta, K.3
Shimi, T.4
Shumaker, D.K.5
Solimando, L.6
Goldman, R.D.7
-
9
-
-
2942643923
-
-
Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, et al. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford Progeria Syndrome 2004; 101:8963-8.
-
(2004)
Accumulation of Mutant Lamin a Causes Progressive Changes in Nuclear Architecture in Hutchinson-Gilford Progeria Syndrome
, vol.101
, pp. 8963-8968
-
-
Goldman, R.D.1
Shumaker, D.K.2
Erdos, M.R.3
Eriksson, M.4
Goldman, A.E.5
Gordon, L.B.6
-
10
-
-
17644373758
-
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
-
Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med 2005; 11:440-5.
-
(2005)
Nat Med
, vol.11
, pp. 440-445
-
-
Scaffidi, P.1
Misteli, T.2
-
11
-
-
33645060977
-
A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria
-
Fong LG, Frost D, M M, Qiao X, Yang SH, Coffinier C, Young SG. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria. Science 2006; 311:1621-3.
-
(2006)
Science
, vol.311
, pp. 1621-1623
-
-
Fong, L.G.1
Frost, D.M.M.2
Qiao, X.3
Yang, S.H.4
Coffinier, C.5
Young, S.G.6
-
12
-
-
33749130220
-
Protein farnesyltransferase inhibitors and progeria
-
Meta M, Yang SH, Bergo MO, Fong LG, Young SG. Protein farnesyltransferase inhibitors and progeria. Trends Mol Med 2006; 12:480-7.
-
(2006)
Trends Mol Med
, vol.12
, pp. 480-487
-
-
Meta, M.1
Yang, S.H.2
Bergo, M.O.3
Fong, L.G.4
Young, S.G.5
-
13
-
-
33746715642
-
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation
-
Yang SH, Meta M, Qiao X, Frost D, Bauch J, Coffinier C, et al. A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation. J Clin Invest 2006; 116:2115-21.
-
(2006)
J Clin Invest
, vol.116
, pp. 2115-2121
-
-
Yang, S.H.1
Meta, M.2
Qiao, X.3
Frost, D.4
Bauch, J.5
Coffinier, C.6
-
14
-
-
46849106102
-
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
-
Varela I, Pereira S, Ugalde AP, Navarro CL, Suárez MF, Cau P, et al. Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging. Nat Med 2008; 14:767-72.
-
(2008)
Nat Med
, vol.14
, pp. 767-772
-
-
Varela, I.1
Pereira, S.2
Ugalde, A.P.3
Navarro, C.L.4
Suárez, M.F.5
Cau, P.6
-
15
-
-
34247356070
-
A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
-
Cao K, Capell BC, Erdos MR, Djabali K, Collins FS. A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells. Proc Natl Acad Sci USA 2007; 104:3939-54.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3939-3954
-
-
Cao, K.1
Capell, B.C.2
Erdos, M.R.3
Djabali, K.4
Collins, F.S.5
-
16
-
-
41649101975
-
The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin
-
McClintock D, Ratner D, Lokuge M, Owens DM, Gordon LB, Collins FS, Djabali K. The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin. PLoS One 2007; 2:1269.
-
(2007)
PLoS One
, vol.2
, pp. 1269
-
-
McClintock, D.1
Ratner, D.2
Lokuge, M.3
Owens, D.M.4
Gordon, L.B.5
Collins, F.S.6
Djabali, K.7
-
17
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974; 77:71-94.
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
18
-
-
28044460514
-
Age-related changes of nuclear architecture in Caenorhabditis elegans
-
Haithcock E, Dayani Y, Neufeld E, Zahand AJ, Feinstein N, Mattout A, et al. Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci USA 2005; 102:16690-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16690-16695
-
-
Haithcock, E.1
Dayani, Y.2
Neufeld, E.3
Zahand, A.J.4
Feinstein, N.5
Mattout, A.6
-
19
-
-
28044460514
-
Age-related changes of nuclear architecture in Caenorhabditis elegans
-
Haithcock E, Dayani Y, Neufeld E, Zahand AJ, Feinstein N, Mattout N, et al. Age-related changes of nuclear architecture in Caenorhabditis elegans. Proc Natl Acad Sci USA 2005; 102:16690-5.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 16690-16695
-
-
Haithcock, E.1
Dayani, Y.2
Neufeld, E.3
Zahand, A.J.4
Feinstein, N.5
Mattout, N.6
-
20
-
-
70349493024
-
Gliotoxin reverses age-dependent nuclear morphology phenotypes, ameliorates motility, but fails to affect lifespan of adult Caenorhabditis elegans
-
Bar DZ, Neufeld E, Feinstein N, Gruenbaum Y. Gliotoxin reverses age-dependent nuclear morphology phenotypes, ameliorates motility, but fails to affect lifespan of adult Caenorhabditis elegans. Cell Motil Cytoskeleton 2009; 66:791-7.
-
(2009)
Cell Motil Cytoskeleton
, vol.66
, pp. 791-797
-
-
Bar, D.Z.1
Neufeld, E.2
Feinstein, N.3
Gruenbaum, Y.4
-
21
-
-
34547927824
-
Barrier to autointegration factor blocks premature cell fusion and maintains adult muscle integrity in C. elegans
-
Margalit A, Neufeld E, Feinstein N, Wilson KL, Podbilewicz B, Gruenbaum Y. Barrier to autointegration factor blocks premature cell fusion and maintains adult muscle integrity in C. elegans. J Cell Biol 2007; 178:661-73.
-
(2007)
J Cell Biol
, vol.178
, pp. 661-673
-
-
Margalit, A.1
Neufeld, E.2
Feinstein, N.3
Wilson, K.L.4
Podbilewicz, B.5
Gruenbaum, Y.6
-
22
-
-
38349110824
-
Laminopathic mutations interfere with the assembly, localization and dynamics of nuclear lamins
-
Wiesel N, Mattout A, Melcer S, Melamed-Book N, Herrmann H, Medalia O, et al. Laminopathic mutations interfere with the assembly, localization and dynamics of nuclear lamins. Proc Natl Acad Sci USA 2008; 105:180-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 180-185
-
-
Wiesel, N.1
Mattout, A.2
Melcer, S.3
Melamed-Book, N.4
Herrmann, H.5
Medalia, O.6
-
23
-
-
48249123448
-
The Parallel Worm Tracker: A platform for measuring average speed and drug-induced paralysis in nematodes
-
Ramot D, Johnson BE, Berry TLJ, Carnell L, Goodman MB. The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS One 2008; 3:2208.
-
(2008)
PLoS One
, vol.3
, pp. 2208
-
-
Ramot, D.1
Johnson, B.E.2
Berry, T.L.J.3
Carnell, L.4
Goodman, M.B.5
-
24
-
-
0037228016
-
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
-
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet 2003; 33:40-8.
-
(2003)
Nat Genet
, vol.33
, pp. 40-48
-
-
Lee, S.S.1
Lee, R.Y.2
Fraser, A.G.3
Kamath, R.S.4
Ahringer, J.5
Ruvkun, G.6
-
25
-
-
0028898579
-
Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans
-
Hara M, Han M. Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans. Proc Natl Acad Sci USA 1995; 92:3333-7.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3333-3337
-
-
Hara, M.1
Han, M.2
-
26
-
-
38949105879
-
Phenotype and course of Hutchinson-Gilford progeria syndrome
-
Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB, et al. Phenotype and course of Hutchinson-Gilford progeria syndrome. N Engl J Med 2008; 358:592-604.
-
(2008)
N Engl J Med
, vol.358
, pp. 592-604
-
-
Merideth, M.A.1
Gordon, L.B.2
Clauss, S.3
Sachdev, V.4
Smith, A.C.5
Perry, M.B.6
-
27
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, Sakano Y, et al. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 2002; 419:808-14.
-
(2002)
Nature
, vol.419
, pp. 808-814
-
-
Herndon, L.A.1
Schmeissner, P.J.2
Dudaronek, J.M.3
Brown, P.A.4
Listner, K.M.5
Sakano, Y.6
-
28
-
-
30844434561
-
Zmpste24, misshapen cell nuclei and progeria-New evidence suggesting that protein farnesylation could be important for disease pathogenesis
-
Young SG, Fong LG, Michaelis S, Prelamin A, Zmpste24, misshapen cell nuclei and progeria-New evidence suggesting that protein farnesylation could be important for disease pathogenesis. J Lipid Res 2005; 46:2531-58.
-
(2005)
J Lipid Res
, vol.46
, pp. 2531-2558
-
-
Young, S.G.1
Fong, L.G.2
Michaelis, S.3
Prelamin, A.4
-
29
-
-
33748993124
-
Molecular bases of progeroid syndromes
-
Navarro CL, Cau P, Lévy N. Molecular bases of progeroid syndromes. Hum Mol Genet 2006; 2:151-61.
-
(2006)
Hum Mol Genet
, vol.2
, pp. 151-161
-
-
Navarro, C.L.1
Cau, P.2
Lévy, N.3
-
30
-
-
33745915850
-
Nuclear lamins: Laminopathies and their role in premature ageing
-
Broers JL, Ramaekers FC, Bonne G, Yaou RB, Hutchison CJ. Nuclear lamins: laminopathies and their role in premature ageing. Physiol Rev 2006; 86:967-1008.
-
(2006)
Physiol Rev
, vol.86
, pp. 967-1008
-
-
Broers, J.L.1
Ramaekers, F.C.2
Bonne, G.3
Yaou, R.B.4
Hutchison, C.J.5
-
31
-
-
26444463068
-
Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome
-
Mallampalli MP, Huyer G, Bendale P, Gelb MH, Michaelis S. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci USA 2005; 102:14416-21.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14416-14421
-
-
Mallampalli, M.P.1
Huyer, G.2
Bendale, P.3
Gelb, M.H.4
Michaelis, S.5
-
32
-
-
22544440839
-
Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation
-
Yang SH, Bergo MO, Toth JI, Qiao X, Hu Y, Sandoval S, et al. Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation. Proc Natl Acad Sci USA 2005; 102:10291-6.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10291-10296
-
-
Yang, S.H.1
Bergo, M.O.2
Toth, J.I.3
Qiao, X.4
Hu, Y.5
Sandoval, S.6
-
33
-
-
12344259997
-
Intranuclear membrane structure formations by CaaX-containing nuclear proteins
-
Ralle T, Grund C, Franke WW, Stick R. Intranuclear membrane structure formations by CaaX-containing nuclear proteins. J Cell Sci 2004; 117:6095-104.
-
(2004)
J Cell Sci
, vol.117
, pp. 6095-6104
-
-
Ralle, T.1
Grund, C.2
Franke, W.W.3
Stick, R.4
-
34
-
-
38949154474
-
Filaments made from A- and B-type lamins differ in structure and organization
-
Goldberg MW, Huttenlauch I, Hutchison CJ, Stick R. Filaments made from A- and B-type lamins differ in structure and organization. J Cell Sci 2008; 121:215-225.
-
(2008)
J Cell Sci
, vol.121
, pp. 215-225
-
-
Goldberg, M.W.1
Huttenlauch, I.2
Hutchison, C.J.3
Stick, R.4
-
35
-
-
12344326099
-
The lamin CxxM motif promotes nuclear membrane growth
-
Prufert K, Vogel A, Krohne G. The lamin CxxM motif promotes nuclear membrane growth. J Cell Sci 2004; 117:6105-16.
-
(2004)
J Cell Sci
, vol.117
, pp. 6105-6116
-
-
Prufert, K.1
Vogel, A.2
Krohne, G.3
-
36
-
-
33645012298
-
Developmental control of nuclear size and shape by Kugelkern and Kurzkern
-
Brandt A, Papagiannouli F, Wagner N, Wilschbrauninger M, Braun M, Furlong EE, et al. Developmental control of nuclear size and shape by Kugelkern and Kurzkern. Curr Biol 2006; 16:543-52.
-
(2006)
Curr Biol
, vol.16
, pp. 543-552
-
-
Brandt, A.1
Papagiannouli, F.2
Wagner, N.3
Wilschbrauninger, M.4
Braun, M.5
Furlong, E.E.6
-
37
-
-
79956088863
-
The measurement and analysis of age-related changes in Caenorhabditis elegans
-
Ed. The C. elegans Research Community, WormBook; DOI/101895/wormbook11371
-
Collins JJ, Huang C, Hughe S, Kornfeld K. The measurement and analysis of age-related changes in Caenorhabditis elegans. WormBook, Ed. The C. elegans Research Community, WormBook; DOI/101895/ wormbook11371, http://wwwwormbookorg2008.
-
WormBook
-
-
Collins, J.J.1
Huang, C.2
Hughe, S.3
Kornfeld, K.4
-
38
-
-
0033214494
-
The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome
-
Kroll M, Arenzana-Seisdedos F, Bachelerie F, Thomas D, Friguet B, Conconi M. The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome. Chem Biol 1999; 6:689-98.
-
(1999)
Chem Biol
, vol.6
, pp. 689-698
-
-
Kroll, M.1
Arenzana-Seisdedos, F.2
Bachelerie, F.3
Thomas, D.4
Friguet, B.5
Conconi, M.6
-
39
-
-
33845998966
-
Prelamin a farnesylation and progeroid syndromes
-
Young SG, Meta M, Yang SH, Fong LG. Prelamin a farnesylation and progeroid syndromes. J Biol Chem 2006; 281:39741-5.
-
(2006)
J Biol Chem
, vol.281
, pp. 39741-39745
-
-
Young, S.G.1
Meta, M.2
Yang, S.H.3
Fong, L.G.4
|