Unresponsive wakefulness syndrome: A new name for the vegetative state or apallic syndrome

BMC Medicine

Volumn 8, Issue , 2010, Pages

  Laureys, Steven ^a   Celesia, Gastone G ^b   Cohadon, Francois ^c   Lavrijsen, Jan ^d   León Carrión, José ^e,n   Sannita, Walter G ^f,g   Sazbon, Leon ^h   Schmutzhard, Erich ⁱ   von Wild, Klaus R ^j,k   Zeman, Adam ^l   Dolce, Giuliano ^m  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

^c University Hospital   (France)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF SEVILLE   (Spain)

^f UNIVERSITY OF GENOA   (Italy)

^g STONY BROOK UNIVERSITY   (United States)

^h TEL AVIV UNIVERSITY   (Israel)

ⁱ UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^j UNIVERSITY OF MÜNSTER   (Germany)

^k AL AZHAR UNIVERSITY   (Egypt)

^l PENINSULA MEDICAL SCHOOL   (United Kingdom)

^m S Anna Institute   (Italy)

ⁿ Ctr for Brain Injury Rehabilitation   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AKINETIC MUTISM; ARTICLE; AWARENESS; BEHAVIOR; CLINICAL ASSESSMENT; DIAGNOSTIC ERROR; EVENT RELATED POTENTIAL; EVOKED RESPONSE; HUMAN; MINIMALLY CONSCIOUS STATE; NEUROIMAGING; PATIENT RIGHT; PERSISTENT VEGETATIVE STATE; UNRESPONSIVE WAKEFULNESS SYNDROME; WAKEFULNESS; NOMENCLATURE; SYNDROME;

AWARENESS; HUMANS; PERSISTENT VEGETATIVE STATE; SYNDROME; TERMINOLOGY AS TOPIC; WAKEFULNESS;

EID: 78549264391     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-8-68     Document Type: Article

References (46)

1. Monti MM, Laureys S, Owen AM. The vegetative state. BMJ 2010, 341:292-296.
2. Kretschmer E. Das apallische Syndrom. Z ges Neurol Psychiat 1940, 169:576-579.
3. Calvet J, Coll J. Meningitis of sinusoid origin with the form of coma vigil. Rev Otoneuroophtalmol 1959, 31:443-445.
4. Jennett B, Plum F. Persistent vegetative state after brain damage. A syndrome in search of a name. Lancet 1972, 1:734-737. 10.1016/S0140-6736(72)90242-5, 4111204.
5. The Multi-Society Task Force on PVS Medical aspects of the persistent vegetative state (1). N Engl J Med 1994, 330:1499-1508. 10.1056/NEJM199405263302107, 7818633, The Multi-Society Task Force on PVS.
6. Jennett B. The vegetative state. Medical facts, ethical and legal dilemmas 2002, Cambridge: Cambridge University Press.
7. Celesia GG. Persistent vegetative state: clinical and ethical issues. Suppl Clin Neurophysiol 2000, 53:460-462. full_text, 12741034.
8. Shewmon DA. A critical analysis of conceptual domains of the vegetative state: sorting fact from fancy. NeuroRehabilitation 2004, 19:343-347.
9. Kotchoubey B. Apallic syndrome is not apallic: Is vegetative state vegetative?. Neuropsychological Rehabilitation 2005, 15:333-356. 10.1080/09602010443000416, 16350976.
10. Schoenle PW, Witzke W. How vegetative is the vegetative state? Preserved semantic processing in VS patients--evidence from N 400 event-related potentials. NeuroRehabilitation 2004, 19:329-334.
11. Jennett B. Thirty years of the vegetative state: clinical, ethical and legal problems. Prog Brain Res 2005, 150:537-543. full_text, 16186047.
12. Bichat M-F-X. Recherches physiologiques sur la vie et la mort 1800, Paris: Brosson Gabon.
13. Borthwick C. The proof of the vegetable: a commentary on medical futility. J Med Ethics 1995, 21:205-208. 10.1136/jme.21.4.205, 1376713, 7473638.
14. Velez GJ. Death of John Paul II and the basic human care for the sick and the dying. Ethics Med 2005, 21:167-177.
15. Laureys S. Permanent vegetative state and persistent vegetative state are not interchangeable terms. British Medical Journal 2000, 16 Oct 2000(9 Sept 2005).., http://bmj.com/cgi/eletters/321/7266/916#10276
16. Lavrijsen JC, van den Bosch JS, Koopmans RT, van Weel C. Prevalence and characteristics of patients in a vegetative state in Dutch nursing homes. J Neurol Neurosurg Psychiatry 2005, 76:1420-1424. 10.1136/jnnp.2004.058198, 1739352, 16170089.
17. Giacino JT, Ashwal S, Childs N, Cranford R, Jennett B, Katz DI, Kelly JP, Rosenberg JH, Whyte J, Zafonte RD, Zasler ND. The minimally conscious state: Definition and diagnostic criteria. Neurology 2002, 58:349-353.
18. Dolce G, Quintieri M, Serra S, Lagani V, Pignolo L. Clinical signs and early prognosis in vegetative state: a decisional tree, data-mining study. Brain Inj 2008, 22:617-623. 10.1080/02699050802132503, 18568716.
19. Dolce G, Sazbon L. The Post-traumatic Vegetative State 2002, New York: Thieme.
20. Childs NL, Mercer WN, Childs HW. Accuracy of diagnosis of persistent vegetative state. Neurology 1993, 43:1465-1467.
21. Andrews K, Murphy L, Munday R, Littlewood C. Misdiagnosis of the vegetative state: retrospective study in a rehabilitation unit. BMJ 1996, 313:13-16. 2351462, 8664760.
22. Schnakers C, Vanhaudenhuyse A, Giacino J, Ventura M, Boly M, Majerus S, Moonen G, Laureys S. Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment. BMC Neurol 2009, 9:35. 10.1186/1471-2377-9-35, 2718857, 19622138.
23. Tavalaro J, Tayson R. Look Up for Yes 1997, New York, NY: Kodansha America, Inc.
24. Voss HU, Uluc AM, Dyke JP, Watts R, Kobylarz EJ, McCandliss BD, Heier LA, Beattie BJ, Hamacher KA, Vallabhajosula S, Goldsmith SJ, Ballon D, Giacino JT, Schiff ND. Possible axonal regrowth in late recovery from the minimally conscious state. J Clin Invest 2006, 116:2005-2011. 10.1172/JCI27021, 1483160, 16823492.
25. Owen AM, Coleman MR, Boly M, Davis MH, Laureys S, Pickard JD. Detecting awareness in the vegetative state. Science 2006, 313:1402. 10.1126/science.1130197, 16959998.
26. Laureys S, Boly M. The changing spectrum of coma. Nat Clin Pract Neurol 2008, 4:544-546. 10.1038/ncpneuro0887, 18762800.
27. Monti MM, Vanhaudenhuyse A, Coleman MR, Boly M, Pickard JD, Tshibanda L, Owen AM, Laureys S. Willful Modulation of Brain Activity in Disorders of Consciousness. N Engl J Med 2010, 362:579-89. 10.1056/NEJMoa0905370, 20130250.
28. Zeman A. Persistent vegetative state. Lancet 1997, 350:795-799. 10.1016/S0140-6736(97)06447-7, 9298013.
29. Machado C, Korein J, Aubert E, Bosch J, Alvarez MA, Rodriguez R, Valdes P, Portela L, Garcia M, Perez N, Chinchilla M, Machado Y, Machado Y. Recognizing a mother's voice in the persistent vegetative state. Clin EEG Neurosci 2007, 38:124-126.
30. Coleman MR, Rodd JM, Davis MH, Johnsrude IS, Menon DK, Pickard JD, Owen AM. Do vegetative patients retain aspects of language comprehension? Evidence from fMRI. Brain 2007, 130:2494-2507. 10.1093/brain/awm170, 17827174.
31. Bekinschtein TA, Shalom DE, Forcato C, Herrera M, Coleman MR, Manes FF, Sigman M. Classical conditioning in the vegetative and minimally conscious state. Nat Neurosci 2009, 12:1343-1349. 10.1038/nn.2391, 19767746.
32. Majerus S, Bruno MA, Schnakers C, Giacino JT, Laureys S. The problem of aphasia in the assessment of consciousness in brain-damaged patients. Prog Brain Res 2009, 177:49-61. full_text, 19818894.
33. Bruno M-A, Fernández-Espejo D, Lehembre R, Tshibanda L, Vanhaudenhuyse A, Gosseries O, Lommers E, Noirhomme Q, Boly M, Napolitani M, et al. Multi-modal imaging in patients with disorders of consciousness showing "functional hemispherectomy". Prog Brain Res 2010,
34. Sazbon L, Groswasser Z. Prolonged coma, vegetative state, post-comatose unawareness: semantics or better understanding?. Brain Inj 1991, 5:1-2. 10.3109/02699059108998504, 2043902.
35. von Wild K, Gerstenbrand F, Dolce G, . AS/VS' Esgo Guidelines for quality management of Apallic Syndrome/Vegetative State. Eur J Trauma Surg 2007, 33:268-292. AS/VS' Esgo.
36. Laureys S, Owen AM, Schiff ND. Brain function in coma, vegetative state, and related disorders. Lancet Neurol 2004, 3:537-546. 10.1016/S1474-4422(04)00852-X, 15324722.
37. Kampfl A, Schmutzhard E, Franz G, Pfausler B, Haring HP, Ulmer H, Felber S, Golaszewski S, Aichner F. Prediction of recovery from post-traumatic vegetative state with cerebral magnetic-resonance imaging. Lancet 1998, 351:1763-1767. 10.1016/S0140-6736(97)10301-4, 9635948.
38. Eilander HJ, Wijnen VJ, Scheirs JG, de Kort PL, Prevo AJ. Children and young adults in a prolonged unconscious state due to severe brain injury: outcome after an early intensive neurorehabilitation programme. Brain Inj 2005, 19:425-436. 10.1080/02699050400025299, 16101265.
39. Cohadon F, Richer E. Deep cerebral stimulation in patients with post-traumatic vegetative state. 25 cases. Neurochirurgie 1993, 39:281-292.
40. von Wild KR. Posttraumatic rehabilitation and one year outcome following acute traumatic brain injury (TBI): data from the well defined population based German Prospective Study 2000-2002. Acta Neurochir Suppl 2008, 101:55-60. full_text, 18642634.
41. Pignolo L, Quintieri M, Sannita WG. The Glasgow outcome scale in vegetative state: a possible source of bias. Brain Inj 2009, 23:1-2. 10.1080/02699050802595873, 19172447.
42. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974, 2:81-84. 10.1016/S0140-6736(74)91639-0, 4136544.
43. Majerus S, Gill-Thwaites H, Andrews K, Laureys S. Behavioral evaluation of consciousness in severe brain damage. Prog Brain Res 2005, 150:397-413. full_text, 16186038.
44. Eilander HJ, van de Wiel M, Wijers M, van Heugten CM, Buljevac D, Lavrijsen JC, Hoenderdaal PL, de Letter-van der Heide L, Wijnen VJ, Scheirs JG, de Kort PL, Prevo AJ. The reliability and validity of the PALOC-s: a post-acute level of consciousness scale for assessment of young patients with prolonged disturbed consciousness after brain injury. Neuropsychol Rehabil 2009, 19:1-27. 10.1080/09602010701694822, 18609020.
45. Laureys S. Death, unconsciousness and the brain. Nat Rev Neurosci 2005, 6:899-909. 10.1038/nrn1789, 16261182.
46. Leon-Carrion J, Martin-Rodriguez JF, Damas-Lopez J, Barroso y Martin JM, Dominguez-Morales MR. Brain function in the minimally conscious state: a quantitative neurophysiological study. Clin Neurophysiol 2008, 119:1506-1514. 10.1016/j.clinph.2008.03.030, 18486547.