Nuclear envelope attachment is not necessary for telomere function in fission yeast

Nucleus

Volumn 1, Issue 6, 2010, Pages 481-486

  Chikashige, Yuji ^a,b   Haraguchi, Tokuko ^a,b   Hiraoka, Yasushi ^a,b  

^a NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Bouquet formation; Fission yeast; Inner nuclear membrane; Nuclear envelope; Silencing; Telomere

Indexed keywords

TELOMERE BINDING PROTEIN; BQT1 PROTEIN, S POMBE; BQT2 PROTEIN, S POMBE; SAD1 PROTEIN, S POMBE; SCHIZOSACCHAROMYCES POMBE PROTEIN;

ARTICLE; CELL ADHESION; CELL NUCLEUS MEMBRANE; CHROMOSOME SIZE; CYTOSKELETON; GENE SILENCING; MEIOTIC PROPHASE I; PROTEIN DEGRADATION; PROTEIN FUNCTION; SPINDLE POLE BODY; TELOMERE; AMINO ACID SEQUENCE; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROPHASE; SCHIZOSACCHAROMYCES; SEQUENCE ALIGNMENT;

SCHIZOSACCHAROMYCETACEAE;

AMINO ACID SEQUENCE; CYTOSKELETON; MOLECULAR SEQUENCE DATA; NUCLEAR ENVELOPE; PROPHASE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE ALIGNMENT; TELOMERE; TELOMERE-BINDING PROTEINS;

EID: 78549260338     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.1.6.13113     Document Type: Article

References (21)

1. Scherthan H. A bouquet makes ends meet. Nat Rev Mol Cell Biol 2001; 2:621-7.
2. Harper L, Golubovskaya I, Cande WZ. A bouquet of chromosomes. J Cell Sci 2004; 117:4025-32.
3. Zickler D. From early homologue recognition to synaptonemal complex formation. Chromosoma 2006; 115:158-74.
4. Chikashige Y, Haraguchi T, Hiraoka Y. Another way to move chromosomes. Chromosoma 2007; 116:497-505.
5. Chikashige Y, Ding DQ, Funabiki H, Haraguchi T, Mashiko S, Yanagida M, et al. Telomereled premeiotic chromosome movement in fission yeast Schizosaccharomyces pombe. Science 1994; 264:270-3.
6. Ding DQ, Chikashige Y, Haraguchi T, Hiraoka Y. Oscillatory nuclear movement in fission yeast meiotic prophase is driven by astral microtubules as revealed by continuous observation of chromosomes and microtubules in living cells. J Cell Sci 1998; 111:701-12.
7. Hiraoka Y. Meiotic telomeres: a matchmaker for homologous chromosomes. Genes Cells 1998; 3:405-13.
8. Chikashige Y, Tsutsumi C, Yamane M, Okamasa K, Haraguchi T, Hiraoka Y. Meiotic proteins Bqt1 and Bqt2 tether telomeres to form the bouquet arrangement of chromosomes. Cell 2006; 125:59-69.
9. Hiraoka Y, Dernburg AF. The SUN rises on meiotic chromosome dynamics. Dev Cell 2009; 17:598-605.
10. Hagan I, Yanagida M. The product of the spindle formation gene sadl+ associates with the fission yeast spindle pole body and is essential for viability. J Cell Biol 1995; 129:1033-47.
11. Niwa O, Shimanuki M, Miki F. Telomere-led bouquet formation facilitates homologous chromosome pairing and restricts ectopic interaction in fission yeast meiosis. EMBO J 2000; 19:3831-40.
12. Miki F, Okazaki K, Shimanuki M, Yamamoto A, Hiraoka Y, Niwa O. The 14 kDa dynein light chainfamily protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast. Mol Biol Cell 2002; 13:930-46.
13. Miki F, Kurabayashi A, Tange Y, Okazaki K, Shimanuki M, Niwa O. Two-hybrid search for proteins that interact with Sad1 and Kms1, two membrane-bound components of the spindle pole body in fission yeast. Mol Genet Genomics 2004; 270:449-61.
14. Shimanuki M, Miki F, Ding DQ, Chikashige Y, Hiraoka Y, Horio T, et al. A novel fission yeast gene, kms1+, is required for the formation of meiotic prophase- specific nuclear architecture. Mol Gen Genet 1997; 254:238-49.
15. Chikashige Y, Yamane M, Okamasa K, Tsutsumi C, Kojidani T, Sato M, et al. Membrane proteins Bqt3 and -4 anchor telomeres to the nuclear envelope to ensure chromosomal bouquet formation. J Cell Biol 2009; 187:413-27.
16. Cooper JP, Nimmo ER, Allshire RC, Cech TR. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature 1997; 385:744-7.
17. Nimmo ER, Pidoux AL, Perry PE, Allshire RC. Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe. Nature 1998; 392:825-8.
18. Cooper JP, Watanabe Y, Nurse P. Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature 1998; 392:828-31.
19. Chikashige Y, Hiraoka Y. Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Curr Biol 2001; 11:1618-23.
20. Kanoh J, Ishikawa F. spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr Biol 2001; 11:1624-30.
21. Chikashige Y, Kurokawa R, Haraguchi T, Hiraoka Y. Meiosis induced by inactivation of Pat1 kinase proceeds with aberrant nuclear positioning of centromeres in the fission yeast Schizosaccharomyces pombe. Genes Cells 2004; 9:671-84.