Interspecific Difference Assay of UDP-glucuronosyltransferase 1A9 Activities in Liver Microsomes by Ultra-performance Liquid Chromatography-tandem Mass Spectrometry

Chinese Journal of Natural Medicines

Volumn 8, Issue 1, 2010, Pages 34-39

  Su, Juan ^a,b   He, Yu Qi ^b   Wang, Chang Hong ^b   Wang, Zheng Tao ^a,b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Interspecific difference; Liver microsomes; Propofol; Propofol glucuronide; UGT1A9; UPLC ESI MS

Indexed keywords

ACETIC ACID; ACETONITRILE; CARBON; GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A9; METACETAMOL; PROPOFOL; URIDINE DIPHOSPHATE;

ACCURACY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG GLUCURONIDATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; FLOW KINETICS; FLOW RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; ION MONITORING; LIVER MICROSOME; MALE; MICHAELIS MENTEN KINETICS; MOUSE; NONHUMAN; RABBIT; RAT; SENSITIVITY AND SPECIFICITY; SHEEP; SPECIES COMPARISON; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 78549242345     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(10)60004-0     Document Type: Article

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