Gemcitabine metabolic and transporter gene polymorphisms are associated with drug toxicity and efficacy in patients with locally advanced pancreatic cancer

Cancer

Volumn 116, Issue 22, 2010, Pages 5325-5335

  Tanaka, Motofumi ^a   Javle, Milind ^a   Dong, Xiaoqun ^a   Eng, Cathy ^a   Abbruzzese, James L ^a   Li, Donghui ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

gemcitabine metabolism; locally advanced pancreatic cancer; nucleoside transporter; single nucleotide polymorphism

Indexed keywords

CISPLATIN; GEMCITABINE; NUCLEOSIDE TRANSPORTER; OXALIPLATIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; DRUG EFFICACY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; OVERALL SURVIVAL; PANCREAS CANCER; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; EUKARYOTIC INITIATION FACTOR-3; FEMALE; GENE EXPRESSION PROFILING; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 78449305536     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25282     Document Type: Article

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