Total synthesis of phytophthora mating hormone α1

Organic Letters

Volumn 12, Issue 22, 2010, Pages 5166-5169

  Wang, Shun Yi ^a   Song, Ping ^a   Chan, Li Yan ^a   Loh, Teck Peng ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE; HORMONE; MATING HORMONE ALPHA1, PHYTOPHTHORA;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; PHYTOPHTHORA; STEREOISOMERISM; SYNTHESIS;

CATALYSIS; DITERPENES; HORMONES; MOLECULAR STRUCTURE; PHYTOPHTHORA; STEREOISOMERISM;

EID: 78449298713     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol102177j     Document Type: Article

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21. See Supporting Information. The absolute stereochemistry of 21 was determined by comparison with our previous results (ref 11).
22. The cross metathesis reaction of 8 with other functionalized tertiary alcohols such as 7a - 7c or 22 under the same conditions affords the corresponded products in much lower yields (< 10%).
23. It was known that there existed an equilibrium between hormone α1 (1) and its hemiacetal 1′. (5, 6)