Cu(I) Tol-BINAP-catalyzed enantioselective Michael reactions of Grignard reagents and unsaturated esters

Journal of the American Chemical Society

Volumn 129, Issue 2, 2007, Pages 276-277

  Wang, Shun Yi ^a,b   Ji, Shun Jun ^b   Loh, Teck Peng ^a  

^a Nanyang Technological University   (Singapore)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; ESTER DERIVATIVE; GRIGNARD REAGENT; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CHIRALITY; ENANTIOSELECTIVITY; MICHAEL ADDITION; REACTION ANALYSIS; STEREOCHEMISTRY;

CATALYSIS; COPPER; ESTERS; INDICATORS AND REAGENTS; LIGANDS; MOLECULAR STRUCTURE; NAPHTHALENES; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM;

EID: 33846250465     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0666046     Document Type: Article

References (17)

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15. 2, and THF gave the product in lower ee (< 80% ee).
16. See Supporting Information.
17. 3c the desired products were obtained with improved yields and enantioselectivities. (Diagram presented)