Injectable chitosan-based hydrogel for implantable drug delivery: Body response and induced variations of structure and composition

Journal of Biomedical Materials Research - Part A

Volumn 95, Issue 4, 2010, Pages 1019-1027

  Sun, Jiali ^a   Jiang, Guoqiang ^a   Qiu, Tingting ^a   Wang, Yujie ^a   Zhang, Kuo ^b   Ding, Fuxin ^a  

^a TSINGHUA UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

body response; chitosan glycerophosphate hydrogel; drug delivery; injectable implant; structural and componential variation

Indexed keywords

BODY RESPONSE; CHITOSAN/GLYCEROPHOSPHATE HYDROGEL; DRUG RELEASE KINETICS; GLYCEROPHOSPHATE; HISTOLOGICAL EXAMINATION; HYDROGEL NETWORKS; IMPLANTABLE DRUG DELIVERY; IN-SITU; IN-VITRO; IN-VIVO; INFLAMMATORY CELLS; INFLAMMATORY RESPONSE; INJECTABLE IMPLANT; LONG-TERM DRUG DELIVERY; OSMOTIC PRESSURE; STRUCTURAL AND COMPONENTIAL VARIATION; THERMO-SENSITIVE HYDROGEL; VASCULARIZATION; WATER LOSS;

CHITIN; CHITOSAN; DRUG DELIVERY; ENCAPSULATION; SOIL MECHANICS;

HYDROGELS;

CHITOSAN; GLYCEROPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RESPONSE; DRUG STRUCTURE; ENCAPSULATION; HISTOLOGY; HYDROGEL; INFLAMMATION; INFLAMMATORY INFILTRATE; MALE; NONHUMAN; OSMOTIC PRESSURE; POROSITY; RAT; VASCULARIZATION; WATER LOSS;

ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CHITOSAN; DRUG DELIVERY SYSTEMS; FREEZE DRYING; GLYCEROPHOSPHATES; HYDROGEL; HYDROGEN-ION CONCENTRATION; IMPLANTS, EXPERIMENTAL; INJECTIONS; MICROSCOPY, ELECTRON, SCANNING; POROSITY; PROSTHESIS IMPLANTATION; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; VISCOSITY; WATER;

EID: 78449296782     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32923     Document Type: Article

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