Clinicopathological significance of expression of Tspan-1, Jab1 and p27 in human hepatocellular carcinoma

Journal of Korean Medical Science

Volumn 25, Issue 10, 2010, Pages 1438-1442

  Chen, L i ^a   Yuan, Daiyue ^a   Wang, Gui lan ^a   Wang, You ^a   Wu, Yuan Yuan ^a   Zhu, Jianwei ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Carcinoma; Hepatocellular; Jab1; P27; Prognosis; Tspan 1

Indexed keywords

COPS5 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MEMBRANE PROTEIN; PEPTIDE HYDROLASE; SIGNAL PEPTIDE; TSPAN1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; FEMALE; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; SURVIVAL RATE;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PEPTIDE HYDROLASES; PROGNOSIS; SURVIVAL RATE;

EID: 78449286192     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2010.25.10.1438     Document Type: Article

References (29)

1. Chen HB, Huang Y, Dai DL, Zhang X, Huang ZW, Zhang QK, Wang HH, Zhang JS, Pan G. Terapeutic effect of transcatheter arterial chemoembolization and percutaneous injection of acetic acids on primary liver cancer. Hepatobiliary Pancreat Dis Int 2004; 3: 55-7.
2. Tang ZY, Ye SL, Liu YK, Qin LX, Sun HC, Ye QH, Wang L, Zhou J, Qiu SJ, Li Y, Ji XN, Liu H, Xia JL, Wu ZQ, Fan J, Ma ZC, Zhou XD, Lin ZY, Liu KD. A decade's studies on metastasis of hepatocellular carcinoma. J Cancer Res Clin Oncol 2004; 130: 187-96.
3. Mazzocca A, Carloni V, Sciammetta S, Cordella C, Pantaleo P, Caldini A, Gentilini P, Pinzani M. Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration. J Hepatol 2002; 37: 322-30.
4. Furuya M, Kato H, Nishimura N, Ishiwata I, Ikeda H, Ito R, Yoshiki T, Ishikura H. Down-regulation of CD9 in human ovarian carcinoma cell might contribute to peritoneal dissemination: Morphologic alteration and reduced expression of beta 1 integrin subsets. Cancer Res 2005; 65: 2617-25.
5. Chen Z, Mustafa T, Trojanowicz B, Brauckhof M, Gimm O, Schmutzler C, Kohrle J, Holzhausen HJ, Kehlen A, Klonisch T, Finke R, Dralle H, Hoang-Vu C. CD82, and CD63 in thyroid cancer. Int J Mol Med 2004; 14: 517-27.
6. Odintsova E, Berditchevski F. Role of the metastasis suppressor tetraspanin CD82/KAI 1 in regulation of signalling in breast cancer cells. Breast Cancer Res 2006; 8 (Suppl 2): P21.
7. Klosek SK, Nakashiro K, Hara S, Goda H, Hasegawa H, Hamakawa H. CD151 regulates HGF-stimulated morphogenesis of human breast cancer cells. Biochem Biophys Res Commun 2009; 379: 1097-100.
8. Serru V, Dessen P, Boucheix C, Rubinstein E. Sequence and expression of seven new tetraspans. Biochim Biophys Acta 2000; 1478: 159-63.
9. Leyden J, Murray D, Moss A, Arumuguma M, Doyle E, McEntee G, O'Keane C, Doran P, MacMathuna P. Net1 and Myeov : computationally identified mediators of gastric cancer. Br J Cancer 2006; 94: 1204-12.
10. Wollscheid V, Kuhne-Heid R, Stein I, Jansen L, Kollner S, Schneider A, Durst M. Identification of a new proliferation-associated protein NET-1/C4.8 characteristic for a subset of high-grade cervical intraepithelial neoplasia and cervical carcinomas. Int J Cancer 2002; 99: 771-5.
11. Chen L, Wang Z, Zhan X, Li DC, Zhu YY, Zhu J. Association of NET-1 gene expression with human hepatocellular carcinoma. Int J Surg Pathol 2007; 15: 346-53.
12. Scholz CJ, Kurzeder C, Koretz K, Windisch J, Kreienberg R, Sauer G, Deissler H. Tspan-1 is a tetraspanin preferentially expressed by mucinous and endometrioid subtypes of human ovarian carcinomas. Cancer Lett 2009; 275: 198-203.
13. Chen L, Li X, Wang GL, Wang Y, Zhu YY, Zhu J. Clinicopathological significance of overexpression of TSPAN1, Ki67 and CD34 in gastric carcinoma. Tumori 2008; 94: 531-8.
14. Chen L, Zhu YY, Zhang XJ, Wang GL, Li XY, He S, Zhang JB, Zhu JW. TSPAN1 protein expression: a significant prognostic indicator for patients with colorectal adenocarcinoma. World J Gastroenterol 2009; 15: 2270-6.
15. Wollscheid V, Kuhne-Heid R, Stein I, Jansen L, Kollner S, Schneider A, Durst M. Identification of a new proliferation-associated protein NET-1/C4.8 characteristic for a subset of high-grade cervical intraepithelial neoplasia and cervical carcinomas. Int J Cancer 2002; 99: 771-5.
16. Ahn J, Hong SA, Lee SE, Kim J, Oh YS, Park SJ, Chung YJ. Cytoplasmic localization of Jab1 and p27 Kip1 might be associated with invasiveness of papillary thyroid carcinoma. Endocr J 2009; 56: 707-13.
17. Esteva FJ, Sahin AA, Rassidakis GZ, Yuan LX, Smith TL, Yang Y, Gilcrease MZ, Cristofanilli M, Nahta R, Pusztai L, Claret FX. Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer. Clin Cancer Res 2003; 9: 5652-9.
18. Goto A, Niki T, Moriyama S, Funata N, Moriyama H, Nishimura Y, Tsuchida R, Kato JY, Fukayama M. Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma. Pathol Int 2004; 54: 675-81.
19. Korbonits M, Chahal HS, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, Harris PE, Farrell WE, Claret FX, Grossman AB. Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors. J Clin Endocrinol Metab 2002; 87: 2635-43.
20. Lu MD, Wang Y, Chen L, Qin J, Li P, Cui XP, Shen AG. Expression and significance of Ser10 phosphorylated p27(kip1) and JAB1 protein in human hepatocellular carcinoma. Zhonghua Bing Li Xue Za Zhi 2007; 36: 840-1.
21. Xu X, Yamamoto H, Sakon M, Yasui M, Ngan CY, Fukunaga H, Morita T, Ogawa M, Nagano H, Nakamori S, Sekimoto M, Matsuura N, Monden M. Overexpression of CDC25A phosphatase is associated with hypergrowth activity and poor prognosis of human hepatocellular carcinomas. Clin Cancer Res 2003; 9: 1764-72.
22. Murray D, Horgan G, Macmathuna P, Doran P. NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer. Br J Cancer 2008; 99: 1322-9.
23. Sui L, Dong Y, Watanabe Y, Yamaguchi F, Sugimoto K, Tokuda M. Clinical significance of Skp2 expression, alone and combined with Jab1 and p27 in epithelial ovarian tumors. Oncol Rep 2006; 15: 765-71.
24. Osoegawa A, Yoshino I, Kometani T, Yamaguchi M, Kameyama T, Yohena T, Maehara Y. Overexpression of Jun activation domain-binding protein 1 in nonsmall cell lung cancer and its significance in p27 expression and clinical features. Cancer 2006; 107: 154-61.
25. Kouvaraki MA, Rassidakis GZ, Tian L, Kumar R, Kittas C, Claret FX. Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27 (Kip1). Cancer Res 2003; 63: 2977-81.
26. Sui L, Dong Y, Watanabe Y, Yamaguchi F, Sugimoto K, Tokuda M. Clinical significance of Skp2 expression, alone and combined with Jab1 and p27 in epithelial ovarian tumors. Oncol Rep 2006; 15: 765-71.
27. Hemler ME. Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol 2005; 6: 801-11.
28. Zoller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat Rev Cancer 2009; 9: 40-55.
29. Shirane M, Harumiya Y, Ishida N, Hirai A, Miyamoto C, Hatakeyama S, Nakayama K, Kitagawa M. Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing. J Biol Chem 1999; 274: 13886-93.