Synergetic analgesia of propentofylline and electroacupuncture by interrupting spinal glial function in rats

Neurochemical Research

Volumn 35, Issue 11, 2010, Pages 1780-1786

  Liang, Ling Li ^a   Yang, Jia Le ^a   Lü, Ning ^a   Gu, Xi Yao ^a   Zhang, Yu Qiu ^a   Zhao, Zhi Qi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Astrocytes; Electroacupuncture; Microglia; Propentofylline; Tetanic stimulation of sciatic nerve

Indexed keywords

PROPENTOFYLLINE;

ALLODYNIA; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN DEPTH STIMULATION; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ELECTROACUPUNCTURE; GLIA CELL; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; LOW DRUG DOSE; MALE; MECHANICAL STIMULATION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; THERAPY EFFECT;

ANALGESIA; ANIMALS; ELECTROACUPUNCTURE; HYPERALGESIA; MALE; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPINAL CORD; TETANY; XANTHINES;

RATTUS;

EID: 78449283616     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0244-x     Document Type: Article

References (31)

1. L Guasti D Richardson M Jhaveri K Eldeeb D Barrett MR Elphick SPH Alexander D Kendall GJ Michael V Chapman 2009 Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain Mol Pain 5 35 10.1186/1744-8069-5-35 19570201
2. D Ziegler 2008 Treatment of diabetic neuropathy and neuropathic pain how far have we come? Diabetes Care 31 S255 S261 1:CAS:528:DC%2BD1cXis1ajtb4%3D 10.2337/dc08-s263 18227494
3. B Ying N Lu YQ Zhang ZQ Zhao 2006 Involvement of spinal glia in tetanically sciatic stimulation-induced bilateral mechanical allodynia in rats Biochem Biophys Res Commun 340 1264 1272 1:CAS:528:DC%2BD28XmsVCrsA%3D%3D 10.1016/j.bbrc.2005.12.139 16406240
4. ZQ Zhao 2008 Neural mechanism underlying acupuncture analgesia Prog Neurobiol 85 355 375 10.1016/j.pneurobio.2008.05.004 18582529
5. BG Hwang BI Min JH Kim HS Na DS Park 2002 Effects of electroacupuncture on the mechanical allodynia in the rat model of neuropathic pain Neurosci Lett 320 49 52 1:CAS:528:DC%2BD38Xht1agsrw%3D 10.1016/S0304-3940(02)00027-7 11849761
6. Y Dai E Kondo T Fukuoka A Tokunaga K Miki K Noguchi 2001 The effect of electroacupuncture on pain behaviors and noxious stimulus-evoked Fos expression in a rat model of neuropathic pain J Pain 2 151 159 1:STN:280: DC%2BD3srksV2ltQ%3D%3D 10.1054/jpai.2001.19964 14622825
7. HN Kim JH Park SK Kim B Sun S Koo SM Choi H Bae BI Min 2008 Electroacupuncture potentiates the antiallodynic effect of intrathecal neostigmine in a rat model of neuropathic pain J Physiol Sci 58 357 360 10.2170/physiolsci.SC008308 18840324
8. SK Kim JH Park SJ Bae JH Kim BG Hwang BI Min DS Park HS Na 2005 Effects of electroacupuncture on cold allodynia in a rat model of neuropathic pain: mediation by spinal adrenergic and serotonergic receptors Exp Neurol 195 430 436 1:CAS:528:DC%2BD2MXhtVSmsbvI 10.1016/j.expneurol.2005.06.018 16054138
9. LR Watkins ED Milligan SF Maier 2001 Spinal cord glia: new players in pain Pain 93 201 205 1:CAS:528:DC%2BD3MXmtFWis7o%3D 10.1016/S0304-3959(01)00359- 1 11514078
10. H Cao YQ Zhang 2008 Spinal glial activation contributes to pathological pain states Neurosci Biobehav Rev 32 972 983 10.1016/j.neubiorev.2008.03.009 18471878
11. S Sun H Cao M Han TT Li HL Pan ZQ Zhao YQ Zhang 2007 New evidence for the involvement of spinal fractalkine receptor in pain facilitation and spinal glial activation in rat model of monoarthritis Pain 129 64 75 1:CAS:528:DC%2BD2sXkt1ehtL4%3D 10.1016/j.pain.2006.09.035 17123734
12. JA DeLeo RP Yezierski 2001 The role of neuroinflammation and neuroimmune activation in persistent pain Pain 90 1 6 1:CAS:528:DC%2BD3MXpt1ylug%3D%3D 10.1016/S0304-3959(00)00490-5 11166964
13. RX Zhang B Liu L Wang K Ren JT Qiao BM Berman L Lao 2005 Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia Pain 118 125 136 1:CAS:528:DC%2BD2MXhtFOmt7%2FI 10.1016/j.pain.2005.08.001 16154703
14. SM Sweitzer P Schubert JA DeLeo 2001 Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain J Pharmacol Exp Ther 297 1210 1217 1:CAS:528:DC%2BD3MXjvVShsLg%3D 11356948
15. A Ledeboer EM Sloane ED Milligan MG Frank JH Mahony SF Maier LR Watkins 2005 Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation Pain 115 71 83 1:CAS:528:DC%2BD2MXjt1Squro%3D 10.1016/j.pain.2005.02.009 15836971
16. S Sun H Cao M Han TT Li ZQ Zhao YQ Zhang 2008 Evidence for suppression of electroacupuncture on spinal glial activation and behavioral hypersensitivity in a rat model of monoarthritis Brain Res Bull 75 83 93 1:STN:280: DC%2BD2sjmtl2lsA%3D%3D 10.1016/j.brainresbull.2007.07.027 18158100
17. S Sun WL Chen PF Wang ZQ Zhao YQ Zhang 2006 Disruption of glial function enhances electroacupuncture analgesia in arthritic rats Exp Neurol 198 294 302 10.1016/j.expneurol.2005.11.011 16490194
18. J Bachynsky P McCracken D Lier K Alloul P Jacobs 2000 Propentofylline treatment for Alzheimer disease and vascular dementia: an economic evaluation based on functional abilities Alzheimer Dis Assoc Disord 14 102 111 1:STN:280:DC%2BD3cvptF2qtg%3D%3D 10.1097/00002093-200004000-00008 10850749
19. B Kittner 1999 Clinical trials of propentofylline in vascular dementia. European/Canadian propentofylline study group Alzheimer Dis Assoc Disord 13 Suppl 3 S166 S171 1:CAS:528:DC%2BD3cXisVeqtg%3D%3D 10609697
20. XC Zhang YQ Zhang ZQ Zhao 2005 Involvement of nitric oxide in long-term potentiation of spinal nociceptive responses in rats Neuroreport 16 1197 1201 1:CAS:528:DC%2BD2MXmtVahsLY%3D 10.1097/00001756-200508010-00013 16012348
21. Liang LL, Wang ZY, Ning L, Yang JL, Zhang YQ, Zhao ZQ (2010) Involvement of nerve injury and activation of peripheral glial cells in tetanic sciatic stimulation-induced persistent pain in rats. J Neurosci Res. doi: 10.1002/jnr.22439
22. ZY Wang YQ Zhang ZQ Zhao 2006 Inhibition of tetanically sciatic stimulation-induced LTP of spinal neurons and Fos expression by disrupting glutamate transporter GLT-1 Neuropharmacology 51 764 772 1:CAS:528: DC%2BD28XovVSqt7c%3D 10.1016/j.neuropharm.2006.05.024 16815482
23. LR Watkins ED Milligan SF Maier 2001 Glial activation: a driving force for pathological pain Trends Neurosci 24 450 455 1:CAS:528:DC%2BD3MXltlymsLw%3D 10.1016/S0166-2236(00)01854-3 11476884
24. ZF Xu GC Wu XD Cao 2002 Effect of electroacupuncture on the expression of interlukin-1beta mRNA after transient focal cerebral ischemia Acupunct Electrother Res 27 29 35 12044018
25. BB Ruzicka RC Thompson SJ Watson H Akil 1996 Interleukin-1 beta-mediated regulation of mu-opioid receptor mRNA in primary astrocyte-enriched cultures J Neurochem 66 425 428 1:CAS:528:DyaK2MXhtVSns7fM 10.1046/j.1471-4159.1996. 66010425.x 8522984
26. BB Ruzicka H Akil 1997 The interleukin-1beta-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte-enriched cultures Neuroscience 79 517 524 1:CAS:528:DyaK2sXktlarsLc%3D 10.1016/S0306-4522(96)00669-0 9200734
27. FE Parkinson AR Paterson JD Young CE Cass 1993 Inhibitory effects of propentofylline on [3H]adenosine influx. A study of three nucleoside transport systems Biochem Pharmacol 46 891 896 1:CAS:528:DyaK2cXktlE%3D 10.1016/0006-2952(93)90499-M 8373440
28. LC Loram JA Harrison EM Sloane MR Hutchinson P Sholar FR Taylor D Berkelhammer BD Coats S Poole ED Milligan SF Maier J Rieger LR Watkins 2009 Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain J Neurosci 29 14015 14025 1:CAS:528:DC%2BD1MXhsVSmsbnE 10.1523/JNEUROSCI.3447-09.2009 19890011
29. SM Sweitzer P Schubert JA DeLeo 2001 Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain J Pharmacol Exp Ther 297 1210 1217 1:CAS:528:DC%2BD3MXjvVShsLg%3D 11356948
30. C Liu F Zhao W Li L Zhu 1994 Role of adenosine in weak electro-acupuncture-induced depression of nociceptive response of spinal dorsal horn neurons in rats Zhen Ci Yan Jiu 19 52 55 7750177
31. PM Lavand'homme JC Eisenach 1999 Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain Pain 80 31 36 10.1016/S0304-3959(98)00193-6 10204715