메뉴 건너뛰기




Volumn 32, Issue 9, 2010, Pages 1080-1090

Clinical trial: Oral zinc in hepatic encephalopathy

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRANCHED CHAIN AMINO ACID; DIURETIC AGENT; ISOLEUCINE; LACTULOSE; LEUCINE; LIVACT; POLAPREZINC; UNCLASSIFIED DRUG; VALINE; ZINC;

EID: 78449271709     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2010.04448.x     Document Type: Article
Times cited : (108)

References (44)
  • 1
    • 0026504209 scopus 로고
    • Pathogenesis and treatment of portal-systemic encephalopathy: An update
    • Butterworth RF. Pathogenesis and treatment of portal-systemic encephalopathy: an update. Dig Dis Sci 1992; 37: 321-7.
    • (1992) Dig Dis Sci , vol.37 , pp. 321-327
    • Butterworth, R.F.1
  • 2
    • 1542515164 scopus 로고    scopus 로고
    • Minimal hepatic encephalopathy impairs fitness to drive
    • Wein C, Koch H, Popp B, Oehler G, Schauder P. Minimal hepatic encephalopathy impairs fitness to drive. Hepatology 2004; 39: 739-45.
    • (2004) Hepatology , vol.39 , pp. 739-745
    • Wein, C.1    Koch, H.2    Popp, B.3    Oehler, G.4    Schauder, P.5
  • 4
    • 33947392621 scopus 로고    scopus 로고
    • Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy
    • Prasad S, Dhiman RK, Duseja A, et al. Lactulose improves cognitive functions and health-related quality of life in patients with cirrhosis who have minimal hepatic encephalopathy. Hepatology 2007; 45: 549-59.
    • (2007) Hepatology , vol.45 , pp. 549-559
    • Prasad, S.1    Dhiman, R.K.2    Duseja, A.3
  • 5
    • 0038047688 scopus 로고    scopus 로고
    • Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: A double blind, randomized trial
    • Marchesini G, Bianchi G, Merli M, et al. Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double blind, randomized trial. Gastroenterology 2003; 124: 1792-801.
    • (2003) Gastroenterology , vol.124 , pp. 1792-1801
    • Marchesini, G.1    Bianchi, G.2    Merli, M.3
  • 6
    • 22144472524 scopus 로고    scopus 로고
    • Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis
    • Muto Y, Sato S, Watanabe A, et al. Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis. Clin Gastroenterol Hepatol 2005; 3: 705-13.
    • (2005) Clin Gastroenterol Hepatol , vol.3 , pp. 705-713
    • Muto, Y.1    Sato, S.2    Watanabe, A.3
  • 7
    • 0019442012 scopus 로고
    • Augmented utilization of branched-chain amino acids by skeletal muscle in decompensated live cirrhosis in special relation to ammonia detoxication
    • Hayashi M, Ohnishi H, Kawade Y, Muto Y, Takahashi Y. Augmented utilization of branched-chain amino acids by skeletal muscle in decompensated live cirrhosis in special relation to ammonia detoxication. Gastroenterol Jpn 1981; 16: 64-70.
    • (1981) Gastroenterol Jpn , vol.16 , pp. 64-70
    • Hayashi, M.1    Ohnishi, H.2    Kawade, Y.3    Muto, Y.4    Takahashi, Y.5
  • 8
    • 0021258341 scopus 로고
    • Comparison of dietary protein with an oral, branched chain-enriched amino acid supplement in chronic portal-systemic encephalopathy: A randomized controlled trial
    • Horst D, Grace ND, Conn HO, et al. Comparison of dietary protein with an oral, branched chain-enriched amino acid supplement in chronic portal-systemic encephalopathy: a randomized controlled trial. Hepatology 1984; 4: 279-87.
    • (1984) Hepatology , vol.4 , pp. 279-287
    • Horst, D.1    Grace, N.D.2    Conn, H.O.3
  • 10
    • 0029942414 scopus 로고    scopus 로고
    • Zinc supplementation and amino acid-nitrogen metabolism in patients with advanced cirrhosis
    • Marchesini G, Fabbri A, Bianchi G, Brizi M, Zoli M. Zinc supplementation and amino acid-nitrogen metabolism in patients with advanced cirrhosis. Hepatology 1996; 23: 1084-92.
    • (1996) Hepatology , vol.23 , pp. 1084-1092
    • Marchesini, G.1    Fabbri, A.2    Bianchi, G.3    Brizi, M.4    Zoli, M.5
  • 11
    • 0021176374 scopus 로고
    • Oral zinc supplementation improves hepatic encephalopathy Results of a randomized controlled trial
    • Reding P, Duchateau J, Bataille C. Oral zinc supplementation improves hepatic encephalopathy. Results of a randomized controlled trial. Lancet 1984; 2: 493-5.
    • (1984) Lancet , vol.2 , pp. 493-495
    • Reding, P.1    Duchateau, J.2    Bataille, C.3
  • 12
    • 0024935034 scopus 로고
    • Correlations between zinc, amino acids and ammonia in liver cirrhosis
    • Grüngreiff K, Presser HJ, Franke D, et al. Correlations between zinc, amino acids and ammonia in liver cirrhosis. Z Gastroenterol 1989; 27: 731-5.
    • (1989) Z Gastroenterol , vol.27 , pp. 731-735
    • Grüngreiff, K.1    Presser, H.J.2    Franke, D.3
  • 13
    • 0027933251 scopus 로고
    • Muscle ammonia and glutamine exchange during chronic liver insufficiency in the rat
    • Dejong CH, Deutz NE, Soeters PB. Muscle ammonia and glutamine exchange during chronic liver insufficiency in the rat. J Hepatol 1994; 21:299-307.
    • (1994) J Hepatol , vol.21 , pp. 299-307
    • Dejong, C.H.1    Deutz, N.E.2    Soeters, P.B.3
  • 14
    • 0018258399 scopus 로고
    • Plasma ammonia and liver ornithine transcarbamoylase activity in zinc-deficient rats
    • Rabbani P, Prasad A. Plasma ammonia and liver ornithine transcarbamoylase activity in zinc-deficient rats. Am J Physiol 1978; 235: E203-6.
    • (1978) Am J Physiol , vol.235
    • Rabbani, P.1    Prasad, A.2
  • 15
    • 0035748549 scopus 로고    scopus 로고
    • Effects of zinc deficiency ? zinc supplementation on ammonia metabolism in patients with decompensated liver cirrhosis
    • Yoshida Y, Higashi T, Nouso K, et al. Effects of zinc deficiency ? zinc supplementation on ammonia metabolism in patients with decompensated liver cirrhosis. Acta Med Okayama 2001; 55: 349-55.
    • (2001) Acta Med Okayama , vol.55 , pp. 349-355
    • Yoshida, Y.1    Higashi, T.2    Nouso, K.3
  • 16
    • 0345299824 scopus 로고    scopus 로고
    • Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
    • Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334: 693-9.
    • (1996) N Engl J Med , vol.334 , pp. 693-699
    • Mazzaferro, V.1    Regalia, E.2    Doci, R.3
  • 17
    • 0036191173 scopus 로고    scopus 로고
    • Hepatic encephalopathy - Definition, nomenclature, diagnosis, and quantification: Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna
    • Ferenci P, Lockwood A, Mullen K, et al. Hepatic encephalopathy - definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 2002; 35: 716-21.
    • (1998) Hepatology , vol.35 , pp. 716-721
    • Ferenci, P.1    Lockwood, A.2    Mullen, K.3
  • 18
    • 0017744177 scopus 로고
    • Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial
    • Conn HO, Leevy CM, Vlahcevic ZR, et al. Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial. Gastroenterology 1977; 72: 573-83.
    • (1977) Gastroenterology , vol.72 , pp. 573-583
    • Conn, H.O.1    Leevy, C.M.2    Vlahcevic, Z.R.3
  • 19
    • 0017645699 scopus 로고
    • Trailmaking and numberconnection tests in the assessment of mental state in portal systemic encephalopathy
    • Conn HO. Trailmaking and numberconnection tests in the assessment of mental state in portal systemic encephalopathy. Am J Dig Dis 1977; 22: 541-50.
    • (1977) Am J Dig Dis , vol.22 , pp. 541-550
    • Conn, H.O.1
  • 20
    • 0001849625 scopus 로고
    • A compendium of tests and assessment techniques
    • Lezak MD, ed., New York: Oxford University Press
    • Lezak MD. A compendium of tests and assessment techniques. In: Lezak MD, ed. Neuropsychological Assessment. New York: Oxford University Press, 1995:381-4.
    • (1995) Neuropsychological Assessment , pp. 381-384
    • Lezak, M.D.1
  • 21
    • 23644461754 scopus 로고    scopus 로고
    • Development of quantitative neuropsychological tests for diagnosis of subclinical hepatic encephalopathy in liver cirrhosis patients and establishment of diagnostic criteriamulticenter collaborative study in Japanese
    • Kato A, Kato M, Ishii H, et al. Development of quantitative neuropsychological tests for diagnosis of subclinical hepatic encephalopathy in liver cirrhosis patients and establishment of diagnostic criteriamulticenter collaborative study in Japanese. Hepatol Res 2004; 30: 71-8.
    • (2004) Hepatol Res , vol.30 , pp. 71-78
    • Kato, A.1    Kato, M.2    Ishii, H.3
  • 22
    • 18744419661 scopus 로고    scopus 로고
    • Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey
    • Fukuhara S, Ware JE Jr, Kosinski M, Wada S, Gandek B. Psychometric and clinical tests of validity of the Japanese SF-36 Health Survey. J Clin Epidemiol 1998; 51: 1045-53.
    • (1998) J Clin Epidemiol , vol.51 , pp. 1045-1053
    • Fukuhara, S.1    Ware, J.E.J.R.2    Kosinski, M.3    Wada, S.4    Gandek, B.5
  • 23
    • 0032211622 scopus 로고    scopus 로고
    • Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan
    • Fukuhara S, Bito S, Green J, Hsiao A, Kurokawa K. Translation, adaptation, and validation of the SF-36 Health Survey for use in Japan. J Clin Epidemiol 1998; 51: 1037-44.
    • (1998) J Clin Epidemiol , vol.51 , pp. 1037-1044
    • Fukuhara, S.1    Bito, S.2    Green, J.3    Hsiao, A.4    Kurokawa, K.5
  • 24
    • 0035175573 scopus 로고    scopus 로고
    • Factors associated with poor health-related quality of life of patients with cirrhosis
    • Italian Study Group for quality of life incirrhosis
    • Marchesini G, Bianchi G, Amodio P, et al. Italian Study Group for quality of life incirrhosis. Factors associated with poor health-related quality of life of patients with cirrhosis. Gastroenterology 2001; 120: 170-8.
    • (2001) Gastroenterology , vol.120 , pp. 170-178
    • Marchesini, G.1    Bianchi, G.2    Amodio, P.3
  • 25
    • 0026877917 scopus 로고
    • The MOS 36-item short-form health survey (SF-36), Conceptual framework and item selection
    • Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). Conceptual framework and item selection. Med Care 1992; 30: 473-83.
    • (1992) Med Care , vol.30 , pp. 473-483
    • Ware Jr., J.E.1    Sherbourne, C.D.2
  • 26
    • 0032212679 scopus 로고    scopus 로고
    • Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project
    • Ware JE Jr, Gandek B. Overview of the SF-36 Health Survey and the International Quality of Life Assessment (IQOLA) Project. J Clin Epidemiol 1998; 51:903-12.
    • (1998) J Clin Epidemiol , vol.51 , pp. 903-912
    • Ware, J.E.J.R.1    Gandek, B.2
  • 28
    • 34347347125 scopus 로고    scopus 로고
    • Evaluation of the effects of combination therapy with branched-chain amino acid and zinc supplements on nitrogen metabolism in liver cirrhosis
    • Hayashi M, Ikezawa K, Ono A, et al. Evaluation of the effects of combination therapy with branched-chain amino acid and zinc supplements on nitrogen metabolism in liver cirrhosis. Hepatol Res 2007; 37: 615-9.
    • (2007) Hepatol Res , vol.37 , pp. 615-619
    • Hayashi, M.1    Ikezawa, K.2    Ono, A.3
  • 29
    • 11144311271 scopus 로고    scopus 로고
    • Ammonia metabolism and hepatic encephalopathy
    • Katayama K. Ammonia metabolism and hepatic encephalopathy. Hepatol Res 2004; 30S: 73-80.
    • (2004) Hepatol Res , vol.30 S , pp. 73-80
    • Katayama, K.1
  • 30
    • 0030701641 scopus 로고    scopus 로고
    • Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy
    • Watanabe A, Sakai T, Sato S, et al. Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy. Hepatology 1997; 26: 1410-4.
    • (1997) Hepatology , vol.26 , pp. 1410-4
    • Watanabe, A.1    Sakai, T.2    Sato, S.3
  • 31
    • 0033831202 scopus 로고    scopus 로고
    • Efficacy of lactulose in cirrhotic patients with subclinical hepatic encephalopathy
    • Dhiman RK, Sawhney MS, Chawla YK, et al. Efficacy of lactulose in cirrhotic patients with subclinical hepatic encephalopathy. Dig Dis Sci 2000; 45: 1549-52.
    • (2000) Dig Dis Sci , vol.45 , pp. 1549-1552
    • Dhiman, R.K.1    Sawhney, M.S.2    Chawla, Y.K.3
  • 32
    • 77950246404 scopus 로고    scopus 로고
    • Rifaximin treatment in hepatic encephalopathy
    • Bass NM, Mullen KD, Sanyal A, et al. Rifaximin treatment in hepatic encephalopathy. N Engl J Med 2010; 362: 1071-81.
    • (2010) N Engl J Med , vol.362 , pp. 1071-1081
    • Bass, N.M.1    Mullen, K.D.2    Sanyal, A.3
  • 33
    • 0043202662 scopus 로고    scopus 로고
    • Influence of hepatic encephalopathy on health-related quality of life in patients with cirrhosis
    • Arguedas MR, DeLawrence TG, McGuire BM. Influence of hepatic encephalopathy on health-related quality of life in patients with cirrhosis. Dig Dis Sci 2003; 48: 1622-6.
    • (2003) Dig Dis Sci , vol.48 , pp. 1622-1626
    • Arguedas, M.R.1    Delawrence, T.G.2    McGuire, B.M.3
  • 34
    • 0034939212 scopus 로고    scopus 로고
    • Health-related quality of life in chronic liver disease: The impact of type and severity of disease
    • Younossi ZM, Boparai N, Price LL, et al. Health-related quality of life in chronic liver disease: the impact of type and severity of disease. Am J Gastroenterol 2001; 96: 2199-205.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2199-2205
    • Younossi, Z.M.1    Boparai, N.2    Price, L.L.3
  • 35
    • 20944447908 scopus 로고    scopus 로고
    • MELD fails to measure quality of life in liver transplant candidates
    • Saab S, Ibrahim AB, Shpaner A, et al. MELD fails to measure quality of life in liver transplant candidates. Liver Transpl 2005; 11: 218-23.
    • (2005) Liver Transpl , vol.11 , pp. 218-223
    • Saab, S.1    Ibrahim, A.B.2    Shpaner, A.3
  • 36
    • 55349145614 scopus 로고    scopus 로고
    • Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: A cross-sectional study
    • Kalaitzakis E, Josefsson A, Bjornsson E. Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional study. BMC Gastroenterol 2008; 8: 46.
    • (2008) BMC Gastroenterol , vol.8 , pp. 46
    • Kalaitzakis, E.1    Josefsson, A.2    Bjornsson, E.3
  • 37
    • 0346996343 scopus 로고    scopus 로고
    • Branched-chain amino acids as a protein- and energy-source in liver cirrhosis
    • Moriwaki H, Miwa Y, Tajika M, et al. Branched-chain amino acids as a protein- and energy-source in liver cirrhosis. Biochem Biophys Res Commun 2004; 313: 405-9.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 405-409
    • Moriwaki, H.1    Miwa, Y.2    Tajika, M.3
  • 38
    • 0032486268 scopus 로고    scopus 로고
    • Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
    • Hara K, Yonezawa K, Weng QP, et al. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J Biol Chem 1998; 273: 14484-94.
    • (1998) J Biol Chem , vol.273 , pp. 14484-14494
    • Hara, K.1    Yonezawa, K.2    Weng, Q.P.3
  • 39
    • 0025908774 scopus 로고
    • Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc] 1st Communication:absorption, Distribution, Metabolism and Excretion after Single Administration to Rats
    • Sano H, Furuta S, Toyama S, et al. Study on the metabolic fate of catena-(S)-[mu-[N alpha-(3-aminopropionyl) histidinato(2-)-N1,N2,O:N tau]-zinc]. 1st communication:absorption, distribution, metabolism and excretion after single administration to rats. Arzneimittelforschung 1991; 41:965-75.
    • (1991) Arzneimittelforschung , vol.41 , pp. 965-75
    • Sano, H.1    Furuta, S.2    Toyama, S.3
  • 41
    • 0033926861 scopus 로고    scopus 로고
    • Preliminary study of combination therapy with interferon-A and zinc in chronic hepatitis C patients with genotype 1b
    • Nagamine T, Takagi H, Takayama H, et al. Preliminary study of combination therapy with interferon-a and zinc in chronic hepatitis C patients with genotype 1b. Biol Trace Elem Res 2000;75: 53-63.
    • (2000) Biol Trace Elem Res , vol.75 , pp. 53-63
    • Nagamine, T.1    Takagi, H.2    Takayama, H.3
  • 42
    • 0032864860 scopus 로고    scopus 로고
    • Development of a disease-specific questionnaire to measure health related quality of life in patients with chronic liver disease
    • Younossi ZM, Grryatt G, Kiwi M, Moparai N, King D. Development of a disease-specific questionnaire to measure health related quality of life in patients with chronic liver disease. Gut 1999; 45:295-300.
    • (1999) Gut , vol.45 , pp. 295-300
    • Younossi, Z.M.1    Grryatt, G.2    Kiwi, M.3    Moparai, N.4    King, D.5
  • 43
    • 0025768460 scopus 로고
    • Short-term oral zinc supplementation does not improve chronic hepatic encephalopathy, Results of a doubleblind crossover trial
    • Riggio O, Ariosto F, Merli M, et al. Short-term oral zinc supplementation does not improve chronic hepatic encephalopathy. Results of a doubleblind crossover trial. Dig Dis Sci 1991;36: 1204-8.
    • (1991) Dig Dis Sci , vol.36 , pp. 1204-1208
    • Riggio, O.1    Ariosto, F.2    Merli, M.3
  • 44
    • 0027274676 scopus 로고
    • Management of hepatic encephalopathy with oral zinc supplementation: A long-term treatment
    • Bresci G, Parisi G, Banti S. Management of hepatic encephalopathy with oral zinc supplementation: a long-term treatment. Eur J Med 1993; 2: 414-6.
    • (1993) Eur J Med , vol.2 , pp. 414-416
    • Bresci, G.1    Parisi, G.2    Banti, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.