Normalized wall index specific and MRI-based stress analysis of atherosclerotic carotid plaques: A study comparing acutely symptomatic and asymptomatic patients

Circulation Journal

Volumn 74, Issue 11, 2010, Pages 2360-2364

  Zhu, Chengcheng ^a   Teng, Zhongzhao ^a   Sadat, Umar ^a   Young, Victoria E ^a   Graves, Martin J ^a   Li, Zhi Yong ^b   Gillard, Jonathan H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SOUTHEAST UNIVERSITY   (China)

Author keywords

Atherosclerosis; Biomechanical stresses; Cartoid; MRI; Plaque burden

Indexed keywords

AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOMECHANICS; CAROTID ARTERY; CAROTID ATHEROSCLEROSIS; COMPUTER ANALYSIS; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FINITE ELEMENT ANALYSIS; HUMAN; IMAGE ANALYSIS; IMAGE QUALITY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MECHANICAL STRESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT CODING; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SIMULATION;

AGED; ASYMPTOMATIC DISEASES; BIOMECHANICS; BRAIN ISCHEMIA; CAROTID ARTERIES; CAROTID STENOSIS; COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE ANGIOGRAPHY; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; STRESS, MECHANICAL;

EID: 78449248201     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-10-0305     Document Type: Article

References (28)

1. Warlow CP. Epidemiology of stroke. Lancet 1998; 352(Suppl 3): SIII-1-SIII-14.
2. MRC European Carotid Surgery Trial: Interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. European Carotid Surgery Trialists' Collaborative Group. Lancet 1991; 337: 1235-1243.
3. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis: North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 1991; 325: 445-453.
4. Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation 1995; 92: 657-671.
5. Sadat U, Li ZY, Graves MJ, Tang TY, Gillard JH. Noninvasive imaging of atheromatous carotid plaques. Nat Clin Pract Cardiovasc Med 2009; 6: 200-209.
6. Underhill HR, Hatsukami TS, Fayad ZA, Fuster V, Yuan C. MRI of carotid atherosclerosis: Clinical implications and future directions. Nat Rev Cardiol 2010; 7: 165-173.
7. Oikawa M, Ota H, Takaya N, Miller Z, Hatsukami TS, Yuan C. Carotid magnetic resonance imaging: A window to study atherosclerosis and identify high-risk plaques. Circ J 2009; 73: 1765-1773.
8. Li ZY, Howarth S, Trivedi RA, U-King-Im JM, Graves MJ, Brown A, et al. Stress analysis of carotid plaque rupture based on in vivo high resolution MRI. J Biomech 2006; 39: 2611-2622.
9. Li ZY, Howarth SP, Tang T, Graves MJ, U-King-Im J, Trivedi RA, et al. Structural analysis and magnetic resonance imaging predict plaque vulnerability: A study comparing symptomatic and asymptomatic individuals. J Vasc Surg 2007; 45: 768-775.
10. Sadat U, Li ZY, Young VE, Graves MJ, Boyle JR, Warburton EL, et al. Finite element analysis of vulnerable atherosclerotic plaques: A comparison of mechanical stresses within carotid plaques of acute and recently symptomatic patients with carotid artery disease. J Neurol Neurosurg Psychiatry 2009; 81: 286-289.
11. Underhill HR, Yuan C, Yarnykh VL, Chu B, Oikawa M, Polissar NL, et al. Arterial remodeling in [corrected] subclinical carotid artery disease. JACC Cardiovasc Imaging 2009; 2: 1381-1389.
12. Li ZY, Tang T, U-King-Im J, Graves M, Sutcliffe M, Gillard JH. Assessment of carotid plaque vulnerability using structural and geometrical determinants. Circ J 2008; 72: 1092-1099.
13. Lusby RJ, Machleder HI, Jeans W, Skidmore R, Woodcock JP, Clifford PC, et al. Vessel wall and blood flow dynamics in arterial disease. Philos Trans R Soc Lond B Biol Sci 1981; 294: 231-239.
14. Lusby RJ, Woodcock JP, Machleder HI, Ferrell LD, Jeans WD, Skidmore R, et al. Transient ischaemic attacks: The static and dynamic morphology of the carotid artery bifurcation. Br J Surg 1982; 69(Suppl): S41-S44.
15. Li ZY, Howarth SP, Tang T, Gillard JH. How critical is fibrous cap thickness to carotid plaque stability? A flow-plaque interaction model. Stroke 2006; 37: 1195-1199.
16. Mitsumori LM, Hatsukami TS, Ferguson MS, Kerwin WS, Cai J, Yuan C. In vivo accuracy of multisequence MR imaging for identifying unstable fibrous caps in advanced human carotid plaques. J Magn Reson Imaging 2003; 17: 410-420.
17. Saam T, Cai J, Ma L, Cai YQ, Ferguson MS, Polissar NL, et al. Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. Radiology 2006; 240: 464-472.
18. Sadat U, Weerakkody RA, Bowden DJ, Young VE, Graves MJ, Li ZY, et al. Utility of high resolution MR imaging to assess carotid plaque morphology: A comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease. Atherosclerosis 2009; 207: 434-439.
19. U-King-Im JM, Tang TY, Patterson A, Graves MJ, Howarth S, Li ZY, et al. Characterisation of carotid atheroma in symptomatic and asymptomatic patients using high-resolution MRI. J Neurol Neurosurg Psychiatry 2008; 79: 905-912.
20. Saam T, Yuan C, Chu B, Takaya N, Underhill H, Cai J, et al. Predictors of carotid atherosclerotic plaque progression as measured by noninvasive magnetic resonance imaging. Atherosclerosis 2007; 194: e34-e42.
21. Tang D, Teng Z, Canton G, Hatsukami TS, Dong L, Huang X, et al. Local critical stress correlates better than global maximum stress with plaque morphological features linked to atherosclerotic plaque vulnerability: An in vivo multi-patient study. Biomed Eng Online 2009; 8: 15.
22. Aglyamov S, Skovoroda A, Xie H, Kim K, Rubin J, O'Donnell M, et al. Model-based reconstructive elasticity imaging using ultrasound. Int J Biomed Imaging 2007; 2007: 11.
23. Tang D, Teng Z, Canton G, Yang C, Ferguson M, Huang X, et al. Sites of rupture in human atherosclerotic carotid plaques are associated with high structural stresses: An in vivo MRI-based 3D fluidstructure interaction study. Stroke 2009; 40: 3258-3263.
24. Redgrave JN, Gallagher P, Lovett JK, Rothwell PM. Critical cap thickness and rupture in symptomatic carotid plaques: The oxford plaque study. Stroke 2008; 39: 1722-1729.
25. Redgrave JN, Lovett JK, Gallagher PJ, Rothwell PM. Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms: The Oxford plaque study. Circulation 2006; 113: 2320-2328.
26. Rothwell PM, Eliasziw M, Gutnikov SA, Fox AJ, Taylor DW, Mayberg MR, et al. Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. Lancet 2003; 361: 107-116.
27. Falk E. Why do plaques rupture? Circulation 1992; 86(6 Suppl): III-30-III-42.
28. Trivedi RA, U-King-Im JM, Graves MJ, Horsley J, Goddard M, Kirkpatrick PJ, et al. MRI-derived measurements of fibrous-cap and lipid-core thickness: The potential for identifying vulnerable carotid plaques in vivo. Neuroradiology 2004; 46: 738-743.